AU2004295148A1 - Developments in biologically active methylene blue derivatives (2) - Google Patents

Developments in biologically active methylene blue derivatives (2) Download PDF

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Publication number
AU2004295148A1
AU2004295148A1 AU2004295148A AU2004295148A AU2004295148A1 AU 2004295148 A1 AU2004295148 A1 AU 2004295148A1 AU 2004295148 A AU2004295148 A AU 2004295148A AU 2004295148 A AU2004295148 A AU 2004295148A AU 2004295148 A1 AU2004295148 A1 AU 2004295148A1
Authority
AU
Australia
Prior art keywords
phenothiazin
compound
ium
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2004295148A
Other languages
English (en)
Inventor
Stanley Beames Brown
John Griffiths
Kirste Joanne Mellish
Cassandra Claire O'grady
David John Howard Roberts
Richard George Tunstall
David Ian Vernon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Photopharmica Ltd
Original Assignee
Photopharmica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0327672.2A external-priority patent/GB0327672D0/en
Priority claimed from GB0329809A external-priority patent/GB0329809D0/en
Application filed by Photopharmica Ltd filed Critical Photopharmica Ltd
Publication of AU2004295148A1 publication Critical patent/AU2004295148A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2004295148A 2003-11-28 2004-11-22 Developments in biologically active methylene blue derivatives (2) Abandoned AU2004295148A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0327672.2 2003-11-28
GBGB0327672.2A GB0327672D0 (en) 2003-11-28 2003-11-28 Developments in biologically active methylene blue derivatives (phenothiazines)
GB0329809A GB0329809D0 (en) 2003-12-23 2003-12-23 Developments in biologically active methylene blue derivatives (2) (phenothiazines)
GB0329809.8 2003-12-23
PCT/GB2004/004918 WO2005054217A1 (en) 2003-11-28 2004-11-22 Developments in biologically active methylene blue derivatives (2)

Publications (1)

Publication Number Publication Date
AU2004295148A1 true AU2004295148A1 (en) 2005-06-16

Family

ID=34655223

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004295148A Abandoned AU2004295148A1 (en) 2003-11-28 2004-11-22 Developments in biologically active methylene blue derivatives (2)

Country Status (7)

Country Link
EP (1) EP1687286A1 (https=)
JP (1) JP2007512297A (https=)
KR (1) KR20060111536A (https=)
AU (1) AU2004295148A1 (https=)
BR (1) BRPI0416928A (https=)
CA (1) CA2547556A1 (https=)
WO (1) WO2005054217A1 (https=)

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CN101084204B (zh) * 2004-09-23 2012-12-05 卫思道制药有限公司 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法
WO2007110630A1 (en) * 2006-03-29 2007-10-04 Wista Laboratories Ltd. Thioninium compounds and their use
SI2004155T1 (en) 2006-03-29 2018-05-31 Wista Laboratories Ltd. Inhibitors of protein aggregation
ES2349322T7 (es) 2006-03-29 2019-10-17 Wista Lab Ltd Sales de 3,7-diamino-10H-fenotiazina y su utilización
MY148145A (en) 2006-07-11 2013-03-15 Wista Lab Ltd Methods of synthesis and/or purification of diaminophenothiazinium compounds
FR2903696B1 (fr) 2006-07-12 2011-02-11 Provence Technologies Procede de purification de composes diaminophenothiazium
US8227459B2 (en) * 2007-04-03 2012-07-24 Prosetta Antiviral Inc. Diamino-phenothiazinyl derivatives as antiviral treatments
FR2920775B1 (fr) 2007-09-07 2009-11-06 Pharma Hydro Dev P H D Soc Par Nouveaux composes diaminophenothiazine, leur procede de preparation et leurs utilisations.
GB2453564A (en) * 2007-10-11 2009-04-15 Liverpool John Moores University Ring-fused derivatives of 3,7-diamino- phenothiazinium & phenoselenazinium salts for use as antimicrobial agents
JP5868955B2 (ja) * 2010-04-30 2016-02-24 プロセッタ アンチバイラル インコーポレイテッド 抗ウイルス化合物
WO2012085250A1 (en) * 2010-12-22 2012-06-28 Ortner Cleanroom Engineering Gmbh Clean room device with movable electromagnetic radiation source
EP2654806B1 (en) * 2010-12-22 2019-05-22 Ortner Cleanroom Engineering GmbH Photodynamic control of microbial growth on surfaces
JP5898701B2 (ja) 2011-02-11 2016-04-13 ウィスタ ラボラトリーズ リミテッド フェノチアジンジアミニウム塩およびそれらの使用
WO2012125983A1 (en) 2011-03-17 2012-09-20 Prosetta Antiviral Inc. Antiviral treatments
EP2694478B1 (en) * 2011-04-04 2018-08-22 Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University Methylene violet analogs as multifunctional radical quenchers for the treatment of mitochondrial dysfunction
EP2699241B1 (en) * 2011-04-20 2016-07-27 Prosetta Antiviral Inc. Antiviral compounds
US20120301904A1 (en) 2011-04-26 2012-11-29 Prosetta Antiviral, Inc Multiprotein assemblies
AU2013341383B2 (en) 2012-11-12 2017-08-24 The Roger B. And Ann K. Mcnamee Trust U/T/A/D Systems and methods for communicating a live event to users using the internet
CN105612148B (zh) * 2013-08-15 2018-09-14 益友制药私人有限公司 用于纯化二氨基吩噻嗪化合物的方法
WO2016031875A1 (ja) 2014-08-27 2016-03-03 富士フイルム株式会社 光線力学療法用組成物、殺菌方法、殺菌システムおよび殺菌システムの作動方法
EP3397623A1 (en) 2015-12-28 2018-11-07 John V. Frangioni Method of preparing diaminophenothiazinium
FR3063495B1 (fr) * 2017-03-02 2019-04-05 Provepharm Life Solutions Procede de preparation de l’iodure de 3,7-bis(dimethylamino)phenothiazine-5-ylium
CA3072418A1 (en) * 2017-08-08 2019-02-14 Board Of Trustees Of Michigan State University Tunable luminescent organic salts for enhanced imaging and photodynamic therapy
US12215234B2 (en) 2019-09-21 2025-02-04 RK Pharma Solutions LLC Process for the purification of methylene blue

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Also Published As

Publication number Publication date
EP1687286A1 (en) 2006-08-09
BRPI0416928A (pt) 2007-01-16
CA2547556A1 (en) 2005-06-16
WO2005054217A1 (en) 2005-06-16
KR20060111536A (ko) 2006-10-27
JP2007512297A (ja) 2007-05-17

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period