AU2004283038B9 - Use of neurokinin antagonists in the treatment of urinary incontinence - Google Patents

Use of neurokinin antagonists in the treatment of urinary incontinence Download PDF

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Publication number
AU2004283038B9
AU2004283038B9 AU2004283038A AU2004283038A AU2004283038B9 AU 2004283038 B9 AU2004283038 B9 AU 2004283038B9 AU 2004283038 A AU2004283038 A AU 2004283038A AU 2004283038 A AU2004283038 A AU 2004283038A AU 2004283038 B9 AU2004283038 B9 AU 2004283038B9
Authority
AU
Australia
Prior art keywords
phenyl
hydrogen
alkyl
formula
azacycloheptan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004283038A
Other languages
English (en)
Other versions
AU2004283038A1 (en
AU2004283038B2 (en
Inventor
Paul William Glue
Kevin Hall Mcallister
Eckhard Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34520229&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2004283038(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2004283038A1 publication Critical patent/AU2004283038A1/en
Application granted granted Critical
Publication of AU2004283038B2 publication Critical patent/AU2004283038B2/en
Publication of AU2004283038B9 publication Critical patent/AU2004283038B9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AU2004283038A 2003-10-27 2004-10-26 Use of neurokinin antagonists in the treatment of urinary incontinence Ceased AU2004283038B9 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51479103P 2003-10-27 2003-10-27
US60/514,791 2003-10-27
PCT/EP2004/012081 WO2005039563A2 (en) 2003-10-27 2004-10-26 Use of neurokinin antagonists in the treatment of urinary incontinence

Publications (3)

Publication Number Publication Date
AU2004283038A1 AU2004283038A1 (en) 2005-05-06
AU2004283038B2 AU2004283038B2 (en) 2008-01-31
AU2004283038B9 true AU2004283038B9 (en) 2008-04-24

Family

ID=34520229

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004283038A Ceased AU2004283038B9 (en) 2003-10-27 2004-10-26 Use of neurokinin antagonists in the treatment of urinary incontinence

Country Status (9)

Country Link
US (1) US7776851B2 (https=)
EP (2) EP1686985A2 (https=)
JP (1) JP2007509184A (https=)
CN (1) CN1874766A (https=)
AU (1) AU2004283038B9 (https=)
BR (1) BRPI0415923A (https=)
CA (1) CA2543552A1 (https=)
MX (1) MXPA06004688A (https=)
WO (1) WO2005039563A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1938804A1 (en) * 2006-12-22 2008-07-02 Novartis AG Pharmaceutical formulation comprising neurokinin antagonist

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007694A1 (en) * 1996-08-22 1998-02-26 Novartis Ag Acylaminoalkenylene-amide derivatives as nk1 and nk2 antagonists
WO2003066062A1 (en) * 2002-02-08 2003-08-14 Novartis Ag Use of acylaminoalkenylene-amide derivatives in functional motility disorders of the viscera

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
FR2700472B1 (fr) * 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
GB0015246D0 (en) * 2000-06-22 2000-08-16 Astrazeneca Ab Method for the treatment of urinary incontinence
US6664253B2 (en) * 2000-10-17 2003-12-16 Boehringer Ingelheim Pharma Kg Neurokinin antagonists
CA2432543A1 (en) * 2000-12-22 2002-07-04 Takeda Chemical Industries, Ltd. Combination drugs
WO2002072145A1 (en) * 2001-03-14 2002-09-19 Ono Pharmaceutical Co., Ltd. Remedies for depression containing ep1 antagonist as the active ingredient
ATE427310T1 (de) * 2002-01-18 2009-04-15 Kyorin Seiyaku Kk Kondensierte bicyclische pyrimidinderivate
ATE370140T1 (de) * 2002-03-26 2007-09-15 Kyorin Seiyaku Kk Kondensierte bicyclische pyrimidinderivate
KR20040099367A (ko) * 2002-03-26 2004-11-26 교린 세이야꾸 가부시키 가이샤 타키키닌 수용체 길항제로서의 축합 바이사이클릭 피리딘 유도체

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007694A1 (en) * 1996-08-22 1998-02-26 Novartis Ag Acylaminoalkenylene-amide derivatives as nk1 and nk2 antagonists
WO2003066062A1 (en) * 2002-02-08 2003-08-14 Novartis Ag Use of acylaminoalkenylene-amide derivatives in functional motility disorders of the viscera

Also Published As

Publication number Publication date
US7776851B2 (en) 2010-08-17
CA2543552A1 (en) 2005-05-06
AU2004283038A1 (en) 2005-05-06
MXPA06004688A (es) 2006-07-05
EP2158910A1 (en) 2010-03-03
EP1686985A2 (en) 2006-08-09
CN1874766A (zh) 2006-12-06
WO2005039563A2 (en) 2005-05-06
BRPI0415923A (pt) 2006-12-26
AU2004283038B2 (en) 2008-01-31
JP2007509184A (ja) 2007-04-12
US20070149504A1 (en) 2007-06-28
WO2005039563A3 (en) 2005-06-30

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Legal Events

Date Code Title Description
SREP Specification republished
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired