AU2004259208B2 - Method for the preparation of controlled release formulations - Google Patents

Method for the preparation of controlled release formulations Download PDF

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Publication number
AU2004259208B2
AU2004259208B2 AU2004259208A AU2004259208A AU2004259208B2 AU 2004259208 B2 AU2004259208 B2 AU 2004259208B2 AU 2004259208 A AU2004259208 A AU 2004259208A AU 2004259208 A AU2004259208 A AU 2004259208A AU 2004259208 B2 AU2004259208 B2 AU 2004259208B2
Authority
AU
Australia
Prior art keywords
poly
group
organic
organic phase
bioactive agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004259208A
Other languages
English (en)
Other versions
AU2004259208A1 (en
Inventor
P. Cook Gary
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Corp
Original Assignee
Evonik Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Corp filed Critical Evonik Corp
Publication of AU2004259208A1 publication Critical patent/AU2004259208A1/en
Application granted granted Critical
Publication of AU2004259208B2 publication Critical patent/AU2004259208B2/en
Assigned to SURMODICS PHARMACEUTICALS, INC. reassignment SURMODICS PHARMACEUTICALS, INC. Request for Assignment Assignors: PR PHARMACEUTICALS, INC.
Assigned to EVONIK CORPORATION reassignment EVONIK CORPORATION Request for Assignment Assignors: SURMODICS PHARMACEUTICALS, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2004259208A 2003-07-15 2004-07-15 Method for the preparation of controlled release formulations Ceased AU2004259208B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48766303P 2003-07-15 2003-07-15
US60/487,663 2003-07-15
PCT/US2004/022816 WO2005009356A2 (en) 2003-07-15 2004-07-15 Method for the preparation of controlled release formulations

Publications (2)

Publication Number Publication Date
AU2004259208A1 AU2004259208A1 (en) 2005-02-03
AU2004259208B2 true AU2004259208B2 (en) 2011-04-28

Family

ID=34102710

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004259208A Ceased AU2004259208B2 (en) 2003-07-15 2004-07-15 Method for the preparation of controlled release formulations

Country Status (9)

Country Link
US (1) US8871269B2 (enExample)
EP (2) EP1651136B1 (enExample)
JP (2) JP5165239B2 (enExample)
CN (2) CN1852687B (enExample)
AU (1) AU2004259208B2 (enExample)
BR (1) BRPI0412059A (enExample)
CA (1) CA2532302C (enExample)
ES (1) ES2625343T3 (enExample)
WO (1) WO2005009356A2 (enExample)

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ES2625343T3 (es) 2003-07-15 2017-07-19 Evonik Corporation Método para la preparación de formulaciones de liberación controlada
EP2462923A3 (en) * 2003-07-18 2012-08-29 Oakwood Laboratories L.L.C. Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
CN100588423C (zh) * 2003-07-23 2010-02-10 Pr药品有限公司 控释组合物
EP2286791B1 (en) * 2003-12-30 2014-03-26 Durect Corporation Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents
EP1679065A1 (en) * 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Controlled release compositions for interferon based on PEGT/PBT block copolymers
US20100290982A1 (en) * 2007-04-13 2010-11-18 University Of North Texas Health Science Center At Fort Worth Solid in oil/water emulsion-diffusion-evaporation formulation for preparing curcumin-loaded plga nanoparticles
BRPI0810899A2 (pt) 2007-04-13 2014-10-29 Univ North Texas Formulação de nanopartículas de plga ativadas carregadas com agente ativo para substâncias nano-terapêuticas anticâncer direcionais.
CA2683698C (en) * 2007-04-19 2013-09-10 Hyun Hee Kwak A biodegradable microsphere composition suitable for the controlled release of glucose controlling peptide and formulation thereof
GB0709322D0 (en) * 2007-05-15 2007-06-20 Nordic Bioscience As Exposure agent for detection of vitamin d
WO2008145183A1 (en) * 2007-05-30 2008-12-04 Nestec S.A. Oil-in-water emulsion and its use for the delayed release of active elements
US8435544B2 (en) 2007-10-08 2013-05-07 Lux Biosciences, Inc. Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
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US8071914B2 (en) * 2007-12-26 2011-12-06 Noboru Oshima Heating apparatus
JP5222550B2 (ja) * 2007-12-27 2013-06-26 財團法人工業技術研究院 徐放性組成物およびその製造方法
US9161943B2 (en) * 2007-12-31 2015-10-20 Industrial Technology Research Institute Sustained release composition and manufacturing method thereof
EP2244679A4 (en) * 2008-02-08 2013-10-09 Qps Llc NON-POLYMERIC COMPOSITIONS FOR CONTROLLED MEDICINAL PRODUCTION
EP2315571A4 (en) * 2008-07-16 2013-05-01 Surmodics Pharmaceuticals Inc METHOD FOR PRODUCING MICROPARTICLES WITH BIOACTIVE PEPTIDES
EP2440185B1 (en) 2009-06-09 2015-04-08 Aurinia Pharmaceuticals Inc. Topical drug delivery systems for ophthalmic use
IN2012DN00407A (enExample) * 2009-08-05 2015-08-21 Pieris Ag
US20110151028A1 (en) * 2009-12-19 2011-06-23 Filiberto Zadini Topical vaginal preparation
ES2362604B1 (es) * 2009-12-22 2012-06-28 Bcn Peptides, S.A. Formulación tópica oftálmica de péptidos.
SG10201501821RA (en) * 2010-03-11 2015-05-28 Wyeth Llc Oral formulations and lipophilic salts of methylnaltrexone
JP5222917B2 (ja) * 2010-09-21 2013-06-26 財團法人工業技術研究院 徐放性組成物およびその製造方法
TWI501781B (zh) * 2010-12-10 2015-10-01 Ind Tech Res Inst 可控制釋放的組合物及其製造方法
US20160151511A1 (en) 2014-12-02 2016-06-02 Antriabio, Inc. Proteins and protein conjugates with increased hydrophobicity
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
US20190117573A1 (en) * 2017-10-19 2019-04-25 Hyalo Technologies, LLC Composition and method of preparation of risperidone extended release preparation
US20230062487A1 (en) * 2020-01-24 2023-03-02 W. L. Gore & Associates, Inc. Sustained-release matrices for adventitial or periadventitial neural ablation and uses thereof
CN111643483B (zh) * 2020-07-06 2022-03-29 济南大学 一种用于制备加兰他敏缓释微球的方法
AU2022226584A1 (en) 2021-02-24 2023-08-17 Oakwood Laboratories, Llc Microsphere formulations comprising lurasidone and methods for making and using the same
CA3216277A1 (en) * 2021-04-23 2022-10-27 Bradley MINROVIC Microsphere formulations comprising multiple non-identical peptides and methods for making the same
US20250009644A1 (en) * 2021-12-02 2025-01-09 University Of Connecticut Long-acting injectable in situ forming biodegradable implants comprising non-steroidal anti-inflammatory drugs
CN116421578A (zh) * 2023-03-31 2023-07-14 辉粒药业(苏州)有限公司 生长抑素类似物缓释微球及其制备方法
CN120958013A (zh) * 2023-04-03 2025-11-14 辉凌公司 制造肽盐的方法

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
BRPI0412059A (pt) 2006-09-05
US20060228414A1 (en) 2006-10-12
JP5165239B2 (ja) 2013-03-21
CN1852687B (zh) 2014-01-22
EP1651136B1 (en) 2017-03-08
WO2005009356A3 (en) 2005-06-09
AU2004259208A1 (en) 2005-02-03
CN1852687A (zh) 2006-10-25
CA2532302C (en) 2016-12-20
WO2005009356A2 (en) 2005-02-03
ES2625343T3 (es) 2017-07-19
EP1651136A4 (en) 2009-07-08
US8871269B2 (en) 2014-10-28
EP1651136A2 (en) 2006-05-03
JP2007524645A (ja) 2007-08-30
JP2011144207A (ja) 2011-07-28
EP2462896A1 (en) 2012-06-13
CA2532302A1 (en) 2005-02-03
CN102935069A (zh) 2013-02-20

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Owner name: SURMODICS PHARMACEUTICALS, INC.

Free format text: FORMER APPLICANT(S): PR PHARMACEUTICALS, INC.

FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: EVONIK CORPORATION

Free format text: FORMER OWNER WAS: SURMODICS PHARMACEUTICALS, INC.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired