AU2004222137A1 - 2-(Butyl-1-sulfonylamino)-N-(1(R)-(6-methoxy-pyridin-3-yl)-propyl)-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound - Google Patents
2-(Butyl-1-sulfonylamino)-N-(1(R)-(6-methoxy-pyridin-3-yl)-propyl)-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound Download PDFInfo
- Publication number
- AU2004222137A1 AU2004222137A1 AU2004222137A AU2004222137A AU2004222137A1 AU 2004222137 A1 AU2004222137 A1 AU 2004222137A1 AU 2004222137 A AU2004222137 A AU 2004222137A AU 2004222137 A AU2004222137 A AU 2004222137A AU 2004222137 A1 AU2004222137 A1 AU 2004222137A1
- Authority
- AU
- Australia
- Prior art keywords
- sulfonylamino
- methoxypyridin
- butyl
- propyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 229960003401 ramipril Drugs 0.000 description 1
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 description 1
- 230000002336 repolarization Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229960002370 sotalol Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000012916 structural analysis Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 125000000565 sulfonamide group Chemical group 0.000 description 1
- 125000006296 sulfonyl amino group Chemical group [H]N(*)S(*)(=O)=O 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000002511 suppository base Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10312073.4 | 2003-03-18 | ||
| DE10312073A DE10312073A1 (de) | 2003-03-18 | 2003-03-18 | 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxy-pyridin-3yl)-propyl]-benzamid, dessen Verwendung als Medikament sowie dieses enthaltende pharmazeutische Zubereitungen |
| PCT/EP2004/002247 WO2004083157A1 (de) | 2003-03-18 | 2004-03-05 | 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, dessen verwendung als medikament sowie dieses enthaltende pharmazeutische zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004222137A1 true AU2004222137A1 (en) | 2004-09-30 |
Family
ID=32920928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004222137A Abandoned AU2004222137A1 (en) | 2003-03-18 | 2004-03-05 | 2-(Butyl-1-sulfonylamino)-N-(1(R)-(6-methoxy-pyridin-3-yl)-propyl)-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1606237A1 (sr) |
| JP (1) | JP2006520343A (sr) |
| KR (1) | KR20050110681A (sr) |
| CN (1) | CN100361943C (sr) |
| AR (1) | AR043622A1 (sr) |
| AU (1) | AU2004222137A1 (sr) |
| BR (1) | BRPI0408441A (sr) |
| CA (1) | CA2519022A1 (sr) |
| DE (1) | DE10312073A1 (sr) |
| HK (1) | HK1086819A1 (sr) |
| HR (1) | HRP20050815A2 (sr) |
| MA (1) | MA27749A1 (sr) |
| MX (1) | MXPA05009763A (sr) |
| MY (1) | MY176510A (sr) |
| NO (1) | NO20054472L (sr) |
| NZ (1) | NZ542476A (sr) |
| PE (1) | PE20050307A1 (sr) |
| RS (1) | RS20050690A (sr) |
| RU (1) | RU2333202C2 (sr) |
| TW (1) | TW200500342A (sr) |
| WO (1) | WO2004083157A1 (sr) |
| ZA (1) | ZA200506328B (sr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004009931A1 (de) * | 2004-02-26 | 2005-09-15 | Aventis Pharma Deutschland Gmbh | Kv1.5-Blocker zur selektiven Steigerung der Vorhofkontraktilität und Behandlung der Herzinsuffizienz |
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| DE102005028845A1 (de) * | 2005-06-22 | 2006-12-28 | Sanofi-Aventis Deutschland Gmbh | Substituierte Heterocyclen, ihre Verwendung als Medikament sowie enthaltende pharmazeutische Zubereitungen |
| WO2007015775A2 (en) * | 2005-07-22 | 2007-02-08 | Merck & Co., Inc. | Potassium channel inhibitors |
| JP5685203B2 (ja) | 2009-05-29 | 2015-03-18 | ラクオリア創薬株式会社 | カルシウムチャネル遮断薬またはナトリウムチャネル遮断薬としてのアリール置換カルボキサミド誘導体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10121003A1 (de) * | 2001-04-28 | 2002-12-19 | Aventis Pharma Gmbh | Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
-
2003
- 2003-03-18 DE DE10312073A patent/DE10312073A1/de not_active Withdrawn
-
2004
- 2004-03-05 CA CA002519022A patent/CA2519022A1/en not_active Abandoned
- 2004-03-05 EP EP04717628A patent/EP1606237A1/de not_active Withdrawn
- 2004-03-05 KR KR1020057017498A patent/KR20050110681A/ko not_active Application Discontinuation
- 2004-03-05 RS YUP-2005/0690A patent/RS20050690A/sr unknown
- 2004-03-05 AU AU2004222137A patent/AU2004222137A1/en not_active Abandoned
- 2004-03-05 JP JP2006504553A patent/JP2006520343A/ja not_active Abandoned
- 2004-03-05 RU RU2005132163/04A patent/RU2333202C2/ru not_active IP Right Cessation
- 2004-03-05 NZ NZ542476A patent/NZ542476A/en unknown
- 2004-03-05 PE PE2004000245A patent/PE20050307A1/es not_active Application Discontinuation
- 2004-03-05 MX MXPA05009763A patent/MXPA05009763A/es active IP Right Grant
- 2004-03-05 WO PCT/EP2004/002247 patent/WO2004083157A1/de active Application Filing
- 2004-03-05 BR BRPI0408441-1A patent/BRPI0408441A/pt not_active IP Right Cessation
- 2004-03-05 CN CNB2004800060168A patent/CN100361943C/zh not_active Expired - Fee Related
- 2004-03-16 AR ARP040100866A patent/AR043622A1/es unknown
- 2004-03-16 TW TW093106899A patent/TW200500342A/zh unknown
- 2004-03-17 MY MYPI20040938A patent/MY176510A/en unknown
-
2005
- 2005-08-08 ZA ZA200506328A patent/ZA200506328B/en unknown
- 2005-09-16 HR HR20050815A patent/HRP20050815A2/xx not_active Application Discontinuation
- 2005-09-19 MA MA28502A patent/MA27749A1/fr unknown
- 2005-09-27 NO NO20054472A patent/NO20054472L/no not_active Application Discontinuation
-
2006
- 2006-06-16 HK HK06106891A patent/HK1086819A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1086819A1 (en) | 2006-09-29 |
| NO20054472L (no) | 2005-09-27 |
| MY176510A (en) | 2020-08-12 |
| RU2005132163A (ru) | 2006-04-10 |
| DE10312073A1 (de) | 2004-09-30 |
| PE20050307A1 (es) | 2005-06-08 |
| CN1756728A (zh) | 2006-04-05 |
| CN100361943C (zh) | 2008-01-16 |
| NZ542476A (en) | 2008-05-30 |
| KR20050110681A (ko) | 2005-11-23 |
| TW200500342A (en) | 2005-01-01 |
| ZA200506328B (en) | 2006-04-26 |
| CA2519022A1 (en) | 2004-09-30 |
| HRP20050815A2 (en) | 2006-09-30 |
| RU2333202C2 (ru) | 2008-09-10 |
| EP1606237A1 (de) | 2005-12-21 |
| AR043622A1 (es) | 2005-08-03 |
| MXPA05009763A (es) | 2006-01-27 |
| BRPI0408441A (pt) | 2006-04-04 |
| RS20050690A (sr) | 2008-04-04 |
| JP2006520343A (ja) | 2006-09-07 |
| WO2004083157A1 (de) | 2004-09-30 |
| MA27749A1 (fr) | 2006-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH Free format text: FORMER APPLICANT(S): AVENTIS PHARMA DEUTSCHLAND GMBH |
|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |