BRPI0408441A - 2-(butil-1-sulfonilamino)-n-[1(r)-(6-metóxi-piridin-3-il)-p ropil]-benzamida, seu emprego como medicamento, assim como preparados farmacêuticos contendo-os - Google Patents

2-(butil-1-sulfonilamino)-n-[1(r)-(6-metóxi-piridin-3-il)-p ropil]-benzamida, seu emprego como medicamento, assim como preparados farmacêuticos contendo-os

Info

Publication number
BRPI0408441A
BRPI0408441A BRPI0408441-1A BRPI0408441A BRPI0408441A BR PI0408441 A BRPI0408441 A BR PI0408441A BR PI0408441 A BRPI0408441 A BR PI0408441A BR PI0408441 A BRPI0408441 A BR PI0408441A
Authority
BR
Brazil
Prior art keywords
benzamide
sulfonylamino
pyridin
methoxy
propyl
Prior art date
Application number
BRPI0408441-1A
Other languages
English (en)
Inventor
Joachim Brendel
Heinz Goegelein
Klaus Wirth
Gert Ulrich Kuerzel
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BRPI0408441A publication Critical patent/BRPI0408441A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

"2-(BUTIL-1-SULFONILAMINO)-N-¢1(R)-(6-METóXIPIRIDIN-3-IL)-P ROPIL!-BENZAMIDA, SEU EMPREGO COMO MEDICAMENTO, ASSIM COMO PREPARADOS FARMACêUTICOS CONTENDO-OS". A presente invenção refere-se a 2-(butil-1-sulfonilamino)-N-¢1(R)(6-metóxi-piridin-3-il)-propil!-benzamid a de fórmula (I), assim como a seus sais farmaceuticamente aceitáveis, sua preparação e emprego, particularmente para tratamento e profilaxia de arritmias atriais, por exemplo fibrilação atrial ou flúter atrial.
BRPI0408441-1A 2003-03-18 2004-03-05 2-(butil-1-sulfonilamino)-n-[1(r)-(6-metóxi-piridin-3-il)-p ropil]-benzamida, seu emprego como medicamento, assim como preparados farmacêuticos contendo-os BRPI0408441A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10312073A DE10312073A1 (de) 2003-03-18 2003-03-18 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxy-pyridin-3yl)-propyl]-benzamid, dessen Verwendung als Medikament sowie dieses enthaltende pharmazeutische Zubereitungen
PCT/EP2004/002247 WO2004083157A1 (de) 2003-03-18 2004-03-05 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, dessen verwendung als medikament sowie dieses enthaltende pharmazeutische zubereitungen

Publications (1)

Publication Number Publication Date
BRPI0408441A true BRPI0408441A (pt) 2006-04-04

Family

ID=32920928

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408441-1A BRPI0408441A (pt) 2003-03-18 2004-03-05 2-(butil-1-sulfonilamino)-n-[1(r)-(6-metóxi-piridin-3-il)-p ropil]-benzamida, seu emprego como medicamento, assim como preparados farmacêuticos contendo-os

Country Status (22)

Country Link
EP (1) EP1606237A1 (pt)
JP (1) JP2006520343A (pt)
KR (1) KR20050110681A (pt)
CN (1) CN100361943C (pt)
AR (1) AR043622A1 (pt)
AU (1) AU2004222137A1 (pt)
BR (1) BRPI0408441A (pt)
CA (1) CA2519022A1 (pt)
DE (1) DE10312073A1 (pt)
HK (1) HK1086819A1 (pt)
HR (1) HRP20050815A2 (pt)
MA (1) MA27749A1 (pt)
MX (1) MXPA05009763A (pt)
MY (1) MY176510A (pt)
NO (1) NO20054472L (pt)
NZ (1) NZ542476A (pt)
PE (1) PE20050307A1 (pt)
RS (1) RS20050690A (pt)
RU (1) RU2333202C2 (pt)
TW (1) TW200500342A (pt)
WO (1) WO2004083157A1 (pt)
ZA (1) ZA200506328B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004009931A1 (de) * 2004-02-26 2005-09-15 Aventis Pharma Deutschland Gmbh Kv1.5-Blocker zur selektiven Steigerung der Vorhofkontraktilität und Behandlung der Herzinsuffizienz
US7569589B2 (en) 2004-07-29 2009-08-04 Merck & Co., Inc. Potassium channel inhibitors
DE102005028845A1 (de) * 2005-06-22 2006-12-28 Sanofi-Aventis Deutschland Gmbh Substituierte Heterocyclen, ihre Verwendung als Medikament sowie enthaltende pharmazeutische Zubereitungen
CA2615440A1 (en) * 2005-07-22 2007-02-08 Merck & Co., Inc. Potassium channel inhibitors
MX2011012712A (es) 2009-05-29 2012-01-30 Raqualia Pharma Inc Derivados de carboxamida sustituidos con arilo como bloqueadores del canal de calcio o sodio.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10121003A1 (de) * 2001-04-28 2002-12-19 Aventis Pharma Gmbh Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
MY176510A (en) 2020-08-12
CN100361943C (zh) 2008-01-16
AU2004222137A1 (en) 2004-09-30
PE20050307A1 (es) 2005-06-08
DE10312073A1 (de) 2004-09-30
ZA200506328B (en) 2006-04-26
KR20050110681A (ko) 2005-11-23
CN1756728A (zh) 2006-04-05
WO2004083157A1 (de) 2004-09-30
JP2006520343A (ja) 2006-09-07
MA27749A1 (fr) 2006-02-01
NZ542476A (en) 2008-05-30
RU2005132163A (ru) 2006-04-10
EP1606237A1 (de) 2005-12-21
MXPA05009763A (es) 2006-01-27
NO20054472L (no) 2005-09-27
RU2333202C2 (ru) 2008-09-10
TW200500342A (en) 2005-01-01
HRP20050815A2 (en) 2006-09-30
RS20050690A (sr) 2008-04-04
HK1086819A1 (en) 2006-09-29
AR043622A1 (es) 2005-08-03
CA2519022A1 (en) 2004-09-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.