AU2004219625B9 - Uses of IL-23 agonists and antagonists; related reagents - Google Patents

Uses of IL-23 agonists and antagonists; related reagents Download PDF

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Publication number
AU2004219625B9
AU2004219625B9 AU2004219625A AU2004219625A AU2004219625B9 AU 2004219625 B9 AU2004219625 B9 AU 2004219625B9 AU 2004219625 A AU2004219625 A AU 2004219625A AU 2004219625 A AU2004219625 A AU 2004219625A AU 2004219625 B9 AU2004219625 B9 AU 2004219625B9
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AU
Australia
Prior art keywords
antibody
antagonist
nucleic acid
seq
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004219625A
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English (en)
Other versions
AU2004219625B2 (en
AU2004219625A1 (en
Inventor
Terrill K. Mcclanahan
Martin Oft
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp and Dohme LLC
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Application filed by Merck Sharp and Dohme Ltd, Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme Ltd
Publication of AU2004219625A1 publication Critical patent/AU2004219625A1/en
Priority to AU2010212372A priority Critical patent/AU2010212372B2/en
Publication of AU2004219625B2 publication Critical patent/AU2004219625B2/en
Application granted granted Critical
Publication of AU2004219625B9 publication Critical patent/AU2004219625B9/en
Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP & DOHME CORP. Request to Amend Deed and Register Assignors: SCHERING CORPORATION
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2004219625A 2003-03-10 2004-03-09 Uses of IL-23 agonists and antagonists; related reagents Ceased AU2004219625B9 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010212372A AU2010212372B2 (en) 2003-03-10 2010-08-16 Uses of IL-23 agonists and antagonists; related reagents

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45367203P 2003-03-10 2003-03-10
US60/453,672 2003-03-10
PCT/US2004/007198 WO2004081190A2 (en) 2003-03-10 2004-03-09 Uses of il-23 agonists and antagonists; related reagents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010212372A Division AU2010212372B2 (en) 2003-03-10 2010-08-16 Uses of IL-23 agonists and antagonists; related reagents

Publications (3)

Publication Number Publication Date
AU2004219625A1 AU2004219625A1 (en) 2004-09-23
AU2004219625B2 AU2004219625B2 (en) 2010-08-19
AU2004219625B9 true AU2004219625B9 (en) 2010-12-23

Family

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Family Applications (2)

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AU2004219625A Ceased AU2004219625B9 (en) 2003-03-10 2004-03-09 Uses of IL-23 agonists and antagonists; related reagents
AU2010212372A Ceased AU2010212372B2 (en) 2003-03-10 2010-08-16 Uses of IL-23 agonists and antagonists; related reagents

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2010212372A Ceased AU2010212372B2 (en) 2003-03-10 2010-08-16 Uses of IL-23 agonists and antagonists; related reagents

Country Status (22)

Country Link
US (4) US7282204B2 (enExample)
EP (2) EP2108658B1 (enExample)
JP (4) JP4605798B2 (enExample)
CN (1) CN1759123B (enExample)
AT (1) ATE440864T1 (enExample)
AU (2) AU2004219625B9 (enExample)
BR (1) BRPI0408247A (enExample)
CA (1) CA2518262C (enExample)
CL (1) CL2004000467A1 (enExample)
CY (1) CY1109468T1 (enExample)
DE (1) DE602004022781D1 (enExample)
DK (1) DK1601694T3 (enExample)
ES (1) ES2330220T3 (enExample)
MX (1) MXPA05009717A (enExample)
NO (1) NO20054630L (enExample)
NZ (2) NZ541898A (enExample)
PL (1) PL1601694T3 (enExample)
PT (1) PT1601694E (enExample)
SI (1) SI1601694T1 (enExample)
TW (2) TWI439285B (enExample)
WO (1) WO2004081190A2 (enExample)
ZA (1) ZA200506879B (enExample)

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CN1942201B (zh) * 2004-02-17 2012-06-20 先灵公司 调节il-23活性的方法;相关试剂
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ES2410406T3 (es) 2005-06-30 2013-07-01 Janssen Biotech, Inc. Anticuerpos anti-IL-23, composiciones, procedimientos y usos
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HUE032131T2 (en) * 2005-08-31 2017-09-28 Merck Sharp & Dohme Constructed anti-IL-23 antibodies
JP2009507023A (ja) 2005-09-01 2009-02-19 シェーリング コーポレイション 自己免疫性眼炎症性疾患を処置するためのil−23およびil−17のアンタゴニストの使用
EP3219328B1 (en) 2005-12-29 2020-06-17 Janssen Biotech, Inc. Human anti-il-23 antibodies, compositions, method and uses
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EP1882699A1 (en) * 2006-07-27 2008-01-30 Heinfried Radeke Regulation of interleukin-23
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Also Published As

Publication number Publication date
AU2004219625B2 (en) 2010-08-19
DE602004022781D1 (de) 2009-10-08
US20100003251A1 (en) 2010-01-07
US8034341B2 (en) 2011-10-11
US20080057058A1 (en) 2008-03-06
TW201141521A (en) 2011-12-01
ZA200506879B (en) 2006-05-31
ATE440864T1 (de) 2009-09-15
MXPA05009717A (es) 2005-10-18
JP4605798B2 (ja) 2011-01-05
CL2004000467A1 (es) 2005-05-06
AU2004219625A1 (en) 2004-09-23
PL1601694T3 (pl) 2010-02-26
AU2010212372A1 (en) 2010-09-09
CY1109468T1 (el) 2014-08-13
SI1601694T1 (sl) 2010-01-29
US7282204B2 (en) 2007-10-16
TWI439285B (zh) 2014-06-01
BRPI0408247A (pt) 2006-03-01
TWI357336B (en) 2012-02-01
TW200505479A (en) 2005-02-16
CA2518262C (en) 2014-05-06
NO20054630D0 (no) 2005-10-07
PT1601694E (pt) 2009-12-03
JP2014005286A (ja) 2014-01-16
EP2108658B1 (en) 2016-06-08
HK1076477A1 (en) 2006-01-20
AU2010212372B2 (en) 2012-12-20
WO2004081190A2 (en) 2004-09-23
EP1601694B1 (en) 2009-08-26
CA2518262A1 (en) 2004-09-23
CN1759123A (zh) 2006-04-12
ES2330220T3 (es) 2009-12-07
NZ567860A (en) 2009-11-27
CN1759123B (zh) 2011-04-13
JP2006520781A (ja) 2006-09-14
US20120034219A1 (en) 2012-02-09
WO2004081190A3 (en) 2005-02-03
US20040223969A1 (en) 2004-11-11
DK1601694T3 (da) 2009-12-14
EP1601694A2 (en) 2005-12-07
EP2108658A1 (en) 2009-10-14
NO20054630L (no) 2005-10-07
JP2007197453A (ja) 2007-08-09
JP2011032275A (ja) 2011-02-17
NZ541898A (en) 2008-07-31

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