AU2003286901B2 - Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease - Google Patents
Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease Download PDFInfo
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- AU2003286901B2 AU2003286901B2 AU2003286901A AU2003286901A AU2003286901B2 AU 2003286901 B2 AU2003286901 B2 AU 2003286901B2 AU 2003286901 A AU2003286901 A AU 2003286901A AU 2003286901 A AU2003286901 A AU 2003286901A AU 2003286901 B2 AU2003286901 B2 AU 2003286901B2
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- botulinum toxin
- botulinum
- toxin
- ulcer
- stomach
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US10/288,734 US7238357B2 (en) | 2002-11-05 | 2002-11-05 | Methods for treating ulcers and gastroesophageal reflux disease |
| US10/288,734 | 2002-11-05 | ||
| PCT/US2003/035199 WO2004041303A1 (en) | 2002-11-05 | 2003-11-03 | Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease |
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| AU2003286901A1 AU2003286901A1 (en) | 2004-06-07 |
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| EP1365800B1 (en) * | 2000-06-28 | 2013-03-06 | Ira Sanders | Methods for using tetanus toxin for benificial purposes in animals (mammals) |
| US7691394B2 (en) * | 2002-05-28 | 2010-04-06 | Botulinum Toxin Research Associates, Inc. | High-potency botulinum toxin formulations |
| US7844338B2 (en) | 2003-02-03 | 2010-11-30 | Enteromedics Inc. | High frequency obesity treatment |
| US7167750B2 (en) * | 2003-02-03 | 2007-01-23 | Enteromedics, Inc. | Obesity treatment with electrically induced vagal down regulation |
| US7613515B2 (en) * | 2003-02-03 | 2009-11-03 | Enteromedics Inc. | High frequency vagal blockage therapy |
| US20040172084A1 (en) * | 2003-02-03 | 2004-09-02 | Knudson Mark B. | Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) |
| US20040226556A1 (en) * | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
| US20040253274A1 (en) * | 2003-06-11 | 2004-12-16 | Allergan, Inc. | Use of a clostridial toxin to reduce appetite |
| US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| EP1982997B1 (en) | 2004-09-01 | 2012-08-08 | Allergan, Inc. | Degradable clostridial toxins |
| US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| JP2008535486A (ja) | 2005-03-15 | 2008-09-04 | アラーガン、インコーポレイテッド | クロストリジウム毒素標的細胞に対する改変された標的能力を有する修飾クロストリジウム毒素 |
| US8105611B2 (en) * | 2005-06-17 | 2012-01-31 | Allergan, Inc. | Treatment of autoimmune disorder with a neurotoxin |
| EP1906923B1 (en) | 2005-07-22 | 2018-01-24 | The Foundry, LLC | Systems and methods for delivery of a therapeutic agent |
| US12433837B2 (en) | 2005-07-22 | 2025-10-07 | The Foundry, Llc | Systems and methods for delivery of a therapeutic agent |
| US9511210B2 (en) * | 2006-05-19 | 2016-12-06 | The Foundry, Llc | Apparatus for toxin delivery to the nasal cavity |
| US10052465B2 (en) | 2005-07-22 | 2018-08-21 | The Foundry, Llc | Methods and systems for toxin delivery to the nasal cavity |
| US8323666B2 (en) | 2005-08-01 | 2012-12-04 | Allergan, Inc. | Botulinum toxin compositions |
| US7822486B2 (en) * | 2005-08-17 | 2010-10-26 | Enteromedics Inc. | Custom sized neural electrodes |
| US7672727B2 (en) * | 2005-08-17 | 2010-03-02 | Enteromedics Inc. | Neural electrode treatment |
| US7910116B2 (en) * | 2005-08-24 | 2011-03-22 | Allergan, Inc. | Use of a botulinum toxin to improve gastric emptying and/or to treat GERD |
| JP4491404B2 (ja) * | 2005-11-07 | 2010-06-30 | 住友電工ハードメタル株式会社 | 刃先交換式チップと刃先交換式隅削りフライスカッタ |
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| US8506970B2 (en) * | 2008-10-14 | 2013-08-13 | Dt Scimed, Llc | Dose and localization of botulinum toxins in skin and muscle |
| CA2745657C (en) | 2008-12-04 | 2022-06-21 | Botulinum Toxin Research Associates, Inc. | Extended length botulinum toxin formulation for human or mammalian use |
| US8753124B2 (en) * | 2009-02-15 | 2014-06-17 | Cheryl Lynn Evans | Method and apparatus for prescribing and preparing a reproducible and customized dysphagia diet |
| US9858831B2 (en) | 2009-02-15 | 2018-01-02 | Cheryl L. Evans | Method for determining and prescribing quantifiable and customized diet for patient suffering from dysphagia |
| US8936471B2 (en) * | 2009-02-15 | 2015-01-20 | Cheryl L. Evans | Flow rate measuring device |
| WO2011038015A1 (en) | 2009-09-24 | 2011-03-31 | Allergan, Inc. | Method of treating osteoporosis with a neurotoxin |
| CN104042322B (zh) | 2009-10-27 | 2017-06-06 | 赫莱拉公司 | 具有可冷却的能量发射组件的递送装置 |
| WO2011060200A1 (en) | 2009-11-11 | 2011-05-19 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
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| EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
| EP2836193B1 (en) | 2012-04-13 | 2018-01-31 | Lubrizol Advanced Materials, Inc. | Compounds which inhibit neuronal exocytosis (ii) |
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| GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
| US10149893B2 (en) | 2013-09-24 | 2018-12-11 | Allergan, Inc. | Methods for modifying progression of osteoarthritis |
| US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
| US11484580B2 (en) | 2014-07-18 | 2022-11-01 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| US9901627B2 (en) | 2014-07-18 | 2018-02-27 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| DK3242884T3 (da) | 2015-01-09 | 2021-04-19 | Ipsen Bioinnovation Ltd | Kationiske neurotoksiner |
| GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (en) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Production of activated clostridial neurotoxins |
| WO2018060351A1 (en) | 2016-09-29 | 2018-04-05 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| EP3758611B1 (en) | 2018-02-26 | 2024-07-24 | Ipsen Biopharm Limited | Ultrasound apparatus to guide injection of non-cytotoxic protease |
| GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
| WO2023097181A1 (en) * | 2021-11-23 | 2023-06-01 | AEON Biopharma, Inc. | Neurotoxin compositions for use in treating digestive disorders |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
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- 2002-11-05 US US10/288,734 patent/US7238357B2/en not_active Expired - Lifetime
-
2003
- 2003-11-03 AT AT03778117T patent/ATE454162T1/de not_active IP Right Cessation
- 2003-11-03 AU AU2003286901A patent/AU2003286901B2/en not_active Ceased
- 2003-11-03 DE DE60330889T patent/DE60330889D1/de not_active Expired - Lifetime
- 2003-11-03 EP EP03778117A patent/EP1558279B1/en not_active Expired - Lifetime
- 2003-11-03 JP JP2004550494A patent/JP4808404B2/ja not_active Expired - Fee Related
- 2003-11-03 CA CA002504932A patent/CA2504932A1/en not_active Abandoned
- 2003-11-03 WO PCT/US2003/035199 patent/WO2004041303A1/en not_active Ceased
- 2003-11-03 CN CNB2003801027980A patent/CN100349613C/zh not_active Expired - Fee Related
- 2003-11-03 ES ES03778117T patent/ES2337892T3/es not_active Expired - Lifetime
- 2003-11-03 MX MXPA05004629A patent/MXPA05004629A/es active IP Right Grant
- 2003-11-03 DK DK03778117.6T patent/DK1558279T3/da active
- 2003-11-03 KR KR1020057007895A patent/KR101072179B1/ko not_active Expired - Fee Related
- 2003-11-03 BR BR0315979-5A patent/BR0315979A/pt not_active IP Right Cessation
- 2003-11-03 NZ NZ539170A patent/NZ539170A/en not_active IP Right Cessation
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| US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
Also Published As
| Publication number | Publication date |
|---|---|
| US20040086531A1 (en) | 2004-05-06 |
| ES2337892T3 (es) | 2010-04-30 |
| AU2003286901A1 (en) | 2004-06-07 |
| US7238357B2 (en) | 2007-07-03 |
| KR101072179B1 (ko) | 2011-10-10 |
| WO2004041303A1 (en) | 2004-05-21 |
| JP4808404B2 (ja) | 2011-11-02 |
| KR20050084657A (ko) | 2005-08-26 |
| WO2004041303B1 (en) | 2004-10-14 |
| NZ539170A (en) | 2007-08-31 |
| DE60330889D1 (de) | 2010-02-25 |
| DK1558279T3 (da) | 2010-05-03 |
| EP1558279B1 (en) | 2010-01-06 |
| MXPA05004629A (es) | 2005-06-08 |
| BR0315979A (pt) | 2005-09-20 |
| CA2504932A1 (en) | 2004-05-21 |
| CN1711103A (zh) | 2005-12-21 |
| JP2006512316A (ja) | 2006-04-13 |
| CN100349613C (zh) | 2007-11-21 |
| EP1558279A1 (en) | 2005-08-03 |
| ATE454162T1 (de) | 2010-01-15 |
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