AU2003279676B2 - Isolation of antisense oligonucleotides - Google Patents

Isolation of antisense oligonucleotides Download PDF

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Publication number
AU2003279676B2
AU2003279676B2 AU2003279676A AU2003279676A AU2003279676B2 AU 2003279676 B2 AU2003279676 B2 AU 2003279676B2 AU 2003279676 A AU2003279676 A AU 2003279676A AU 2003279676 A AU2003279676 A AU 2003279676A AU 2003279676 B2 AU2003279676 B2 AU 2003279676B2
Authority
AU
Australia
Prior art keywords
antisense oligonucleotides
oligonucleotides
thioated
antisense
imac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003279676A
Other languages
English (en)
Other versions
AU2003279676A1 (en
Inventor
Kjell Eriksson
Bo-Lennart Johansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Publication of AU2003279676A1 publication Critical patent/AU2003279676A1/en
Assigned to GE HEALTHCARE BIO-SCIENCES AB reassignment GE HEALTHCARE BIO-SCIENCES AB Request for Assignment Assignors: AMERSHAM BIOSCIENCES AB
Application granted granted Critical
Publication of AU2003279676B2 publication Critical patent/AU2003279676B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J45/00—Ion-exchange in which a complex or a chelate is formed; Use of material as complex or chelate forming ion-exchangers; Treatment of material for improving the complex or chelate forming ion-exchange properties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003279676A 2002-11-28 2003-11-17 Isolation of antisense oligonucleotides Ceased AU2003279676B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0203521-0 2002-11-28
SE0203521A SE0203521D0 (sv) 2002-11-28 2002-11-28 Isolation of antisense oligonucleotides
PCT/SE2003/001784 WO2004048569A1 (en) 2002-11-28 2003-11-17 Isolation of antisense oligonucleotides

Publications (2)

Publication Number Publication Date
AU2003279676A1 AU2003279676A1 (en) 2004-06-18
AU2003279676B2 true AU2003279676B2 (en) 2009-01-22

Family

ID=20289700

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003279676A Ceased AU2003279676B2 (en) 2002-11-28 2003-11-17 Isolation of antisense oligonucleotides

Country Status (11)

Country Link
US (1) US7368561B2 (enExample)
EP (1) EP1578968B1 (enExample)
JP (1) JP2006507825A (enExample)
CN (1) CN100343390C (enExample)
AT (1) ATE325191T1 (enExample)
AU (1) AU2003279676B2 (enExample)
CA (1) CA2506196A1 (enExample)
DE (1) DE60305075T2 (enExample)
ES (1) ES2263038T3 (enExample)
SE (1) SE0203521D0 (enExample)
WO (1) WO2004048569A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100016564A1 (en) * 2006-05-30 2010-01-21 Ge Healthcare Bio-Sciences Ab Method of preparing an immobilised metal ion chromatography adsorbent and methods of purifying proteins, peptides or polynucleotides
JP2009073819A (ja) * 2007-08-29 2009-04-09 Fujifilm Corp 生理活性物質の精製方法
US8753868B2 (en) 2008-08-04 2014-06-17 General Electric Company Method and system for selective isolation of target biological molecules in a general purpose system
US7738454B1 (en) * 2008-09-30 2010-06-15 Juniper Networks, Inc. Methods and apparatus related to packet classification based on range values
CN110346493B (zh) * 2019-05-23 2021-01-05 中国人民解放军军事科学院军事医学研究院 检测猕猴血浆中中期因子反义寡核苷酸含量的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000435A2 (en) * 1996-07-03 1998-01-08 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
WO1999009045A1 (en) * 1997-08-20 1999-02-25 Somagenics, Inc. Antisense and antigene therapeutics with improved binding properties and methods for their use
WO2002046398A2 (en) * 2000-11-06 2002-06-13 The University Of Houston System Nucleic acid separation using immobilized metal affinity chromatography

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000435A2 (en) * 1996-07-03 1998-01-08 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
WO1999009045A1 (en) * 1997-08-20 1999-02-25 Somagenics, Inc. Antisense and antigene therapeutics with improved binding properties and methods for their use
WO2002046398A2 (en) * 2000-11-06 2002-06-13 The University Of Houston System Nucleic acid separation using immobilized metal affinity chromatography

Also Published As

Publication number Publication date
ATE325191T1 (de) 2006-06-15
CN1717484A (zh) 2006-01-04
CN100343390C (zh) 2007-10-17
ES2263038T3 (es) 2006-12-01
DE60305075T2 (de) 2006-12-14
AU2003279676A1 (en) 2004-06-18
US20060003331A1 (en) 2006-01-05
US7368561B2 (en) 2008-05-06
CA2506196A1 (en) 2004-06-10
WO2004048569A1 (en) 2004-06-10
JP2006507825A (ja) 2006-03-09
EP1578968A1 (en) 2005-09-28
SE0203521D0 (sv) 2002-11-28
EP1578968B1 (en) 2006-05-03
DE60305075D1 (de) 2006-06-08

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: GE HEALTHCARE BIO-SCIENCES AB

Free format text: FORMER NAME: AMERSHAM BIOSCIENCES AB

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired