AU2003272827B2 - Method for treating patients with massive blood loss - Google Patents

Method for treating patients with massive blood loss Download PDF

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Publication number
AU2003272827B2
AU2003272827B2 AU2003272827A AU2003272827A AU2003272827B2 AU 2003272827 B2 AU2003272827 B2 AU 2003272827B2 AU 2003272827 A AU2003272827 A AU 2003272827A AU 2003272827 A AU2003272827 A AU 2003272827A AU 2003272827 B2 AU2003272827 B2 AU 2003272827B2
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AU
Australia
Prior art keywords
hemoglobin
solution
polymerized
molecular weight
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2003272827A
Other languages
English (en)
Other versions
AU2003272827A1 (en
Inventor
Richard E. Dewoskin
Marc D. Doubleday
Steven A. Gould
George A. Hides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northfield Laboratories Inc
Original Assignee
Northfield Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northfield Laboratories Inc filed Critical Northfield Laboratories Inc
Publication of AU2003272827A1 publication Critical patent/AU2003272827A1/en
Application granted granted Critical
Publication of AU2003272827B2 publication Critical patent/AU2003272827B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2003272827A 2002-10-03 2003-10-03 Method for treating patients with massive blood loss Expired - Fee Related AU2003272827B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41593502P 2002-10-03 2002-10-03
US60/415,935 2002-10-03
PCT/US2003/031377 WO2004037279A1 (en) 2002-10-03 2003-10-03 Method for treating patients with massive blood loss

Publications (2)

Publication Number Publication Date
AU2003272827A1 AU2003272827A1 (en) 2004-05-13
AU2003272827B2 true AU2003272827B2 (en) 2009-03-19

Family

ID=32176456

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003272827A Expired - Fee Related AU2003272827B2 (en) 2002-10-03 2003-10-03 Method for treating patients with massive blood loss

Country Status (11)

Country Link
US (1) US7291592B2 (enExample)
EP (1) EP1553968A4 (enExample)
JP (1) JP2006502231A (enExample)
CN (1) CN1703235A (enExample)
AU (1) AU2003272827B2 (enExample)
CA (1) CA2499459A1 (enExample)
MX (1) MXPA05003340A (enExample)
NO (1) NO20051390L (enExample)
RU (1) RU2325924C2 (enExample)
WO (1) WO2004037279A1 (enExample)
ZA (1) ZA200502307B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050049707A1 (en) * 2003-08-29 2005-03-03 Ferree Bret A. Cemented artificial disc replacements
US7747315B2 (en) * 2002-01-15 2010-06-29 Board Of Regents, The University Of Texas System Methods and compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
EP1978802A2 (en) * 2006-01-24 2008-10-15 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
WO2008009635A2 (en) * 2006-07-17 2008-01-24 Novo Nordisk Health Care Ag Factor viia analogues with increased activity for treating thrombocytopenia
RU2361608C1 (ru) * 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
RU2452519C1 (ru) * 2011-03-25 2012-06-10 Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ компенсации глобулярного объема крови и иммуномодулирующего воздействия при трансплантации
EP3655019A4 (en) 2017-07-18 2021-04-21 Virtech Bio, Inc. BLOOD SUBSTITUTES INCLUDING HEMOGLOBIN AND METHODS OF MANUFACTURING

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464814A (en) 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
US4826811A (en) 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5854209A (en) 1995-03-23 1998-12-29 Biopure Corporation Method for oxygenating tissue having reduced red blood cell flow
US5084558A (en) 1987-10-13 1992-01-28 Biopure Corporation Extra pure semi-synthetic blood substitute
US5955581A (en) 1986-11-10 1999-09-21 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
AU705225B2 (en) * 1995-03-23 1999-05-20 Biopure Corporation Stable polymerized hemoglobin blood substitute
US20020065211A1 (en) 1995-03-23 2002-05-30 Biopure Corporation Increasing function of organs having reduced red blood cell flow
US5895810A (en) 1995-03-23 1999-04-20 Biopure Corporation Stable polymerized hemoglobin and use thereof
US6150507A (en) 1995-03-23 2000-11-21 Biopure Corporation Method for producing a purified hemoglobin product
US6288027B1 (en) 1995-03-23 2001-09-11 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US5691452A (en) 1995-03-23 1997-11-25 Biopure Corporation Method for preserving a hemoglobin blood substitute
US6271351B1 (en) 1995-03-23 2001-08-07 Biopure Corporation Method for preserving a hemoglobin blood substitute
US5691453A (en) 1995-06-07 1997-11-25 Biopure Corporation Separation of polymerized hemoglobin from unpolymerized hemoglobin on hydroxyapatite using HPLC
SK134398A3 (en) * 1996-03-28 2001-01-18 Northfield Lab Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same
US5890852A (en) * 1998-03-17 1999-04-06 Emerson Electric Company Thread cutting die and method of manufacturing same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GOULD et al,The Journal of Trauma, 1997, Vol 43, pages 325-332. *
SEHGAL et al,Surgery, April 1984, Vol 95, No 4, pages 433-438. *

Also Published As

Publication number Publication date
NO20051390L (no) 2005-05-30
CA2499459A1 (en) 2004-05-06
US7291592B2 (en) 2007-11-06
AU2003272827A1 (en) 2004-05-13
RU2005113240A (ru) 2005-12-10
RU2325924C2 (ru) 2008-06-10
MXPA05003340A (es) 2005-07-05
WO2004037279A1 (en) 2004-05-06
US20040067876A1 (en) 2004-04-08
CN1703235A (zh) 2005-11-30
JP2006502231A (ja) 2006-01-19
EP1553968A4 (en) 2009-06-24
EP1553968A1 (en) 2005-07-20
ZA200502307B (en) 2005-11-30

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Legal Events

Date Code Title Description
MK25 Application lapsed reg. 22.2i(2) - failure to pay acceptance fee