RU2325924C2 - Способ лечения пациентов с массивной потерей крови - Google Patents

Способ лечения пациентов с массивной потерей крови Download PDF

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Publication number
RU2325924C2
RU2325924C2 RU2005113240/14A RU2005113240A RU2325924C2 RU 2325924 C2 RU2325924 C2 RU 2325924C2 RU 2005113240/14 A RU2005113240/14 A RU 2005113240/14A RU 2005113240 A RU2005113240 A RU 2005113240A RU 2325924 C2 RU2325924 C2 RU 2325924C2
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RU
Russia
Prior art keywords
hemoglobin
solution
polymerized
blood
molecular weight
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RU2005113240/14A
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English (en)
Russian (ru)
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RU2005113240A (ru
Inventor
Стивен А. ГОУЛД (US)
Стивен А. ГОУЛД
Ричард Э. ДЬЮВОСКИН (US)
Ричард Э. ДЬЮВОСКИН
Марк Д. ДАБЛДЭЙ (US)
Марк Д. ДАБЛДЭЙ
Джордж А. ХАЙДС (US)
Джордж А. ХАЙДС
Original Assignee
Нортфилд Лэборэтериз, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2005113240/14A 2002-10-03 2003-10-03 Способ лечения пациентов с массивной потерей крови RU2325924C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41593502P 2002-10-03 2002-10-03
US60/415,935 2002-10-03

Publications (2)

Publication Number Publication Date
RU2005113240A RU2005113240A (ru) 2005-12-10
RU2325924C2 true RU2325924C2 (ru) 2008-06-10

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RU2005113240/14A RU2325924C2 (ru) 2002-10-03 2003-10-03 Способ лечения пациентов с массивной потерей крови

Country Status (11)

Country Link
US (1) US7291592B2 (enExample)
EP (1) EP1553968A4 (enExample)
JP (1) JP2006502231A (enExample)
CN (1) CN1703235A (enExample)
AU (1) AU2003272827B2 (enExample)
CA (1) CA2499459A1 (enExample)
MX (1) MXPA05003340A (enExample)
NO (1) NO20051390L (enExample)
RU (1) RU2325924C2 (enExample)
WO (1) WO2004037279A1 (enExample)
ZA (1) ZA200502307B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2452519C1 (ru) * 2011-03-25 2012-06-10 Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ компенсации глобулярного объема крови и иммуномодулирующего воздействия при трансплантации
RU2861484C1 (ru) * 2025-11-11 2026-05-05 Общество с ограниченной ответственностью "НеоГемовет" (ООО "НеоГемовет") Средство для инфузии, восстанавливающее объем циркулирующей крови при кровопотерях у животных

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050049707A1 (en) * 2003-08-29 2005-03-03 Ferree Bret A. Cemented artificial disc replacements
US7747315B2 (en) * 2002-01-15 2010-06-29 Board Of Regents, The University Of Texas System Methods and compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
EP1978802A2 (en) * 2006-01-24 2008-10-15 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
WO2008009635A2 (en) * 2006-07-17 2008-01-24 Novo Nordisk Health Care Ag Factor viia analogues with increased activity for treating thrombocytopenia
RU2361608C1 (ru) * 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
EP3655019A4 (en) 2017-07-18 2021-04-21 Virtech Bio, Inc. BLOOD SUBSTITUTES INCLUDING HEMOGLOBIN AND METHODS OF MANUFACTURING

Citations (3)

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Publication number Priority date Publication date Assignee Title
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
EP1093720A1 (en) * 1995-03-23 2001-04-25 Biopure Corporation Stable polymerized hemoglobin blood-substitute

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US4826811A (en) 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5854209A (en) 1995-03-23 1998-12-29 Biopure Corporation Method for oxygenating tissue having reduced red blood cell flow
US5084558A (en) 1987-10-13 1992-01-28 Biopure Corporation Extra pure semi-synthetic blood substitute
US5955581A (en) 1986-11-10 1999-09-21 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US20020065211A1 (en) 1995-03-23 2002-05-30 Biopure Corporation Increasing function of organs having reduced red blood cell flow
US5895810A (en) 1995-03-23 1999-04-20 Biopure Corporation Stable polymerized hemoglobin and use thereof
US6150507A (en) 1995-03-23 2000-11-21 Biopure Corporation Method for producing a purified hemoglobin product
US6288027B1 (en) 1995-03-23 2001-09-11 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US5691452A (en) 1995-03-23 1997-11-25 Biopure Corporation Method for preserving a hemoglobin blood substitute
US6271351B1 (en) 1995-03-23 2001-08-07 Biopure Corporation Method for preserving a hemoglobin blood substitute
US5691453A (en) 1995-06-07 1997-11-25 Biopure Corporation Separation of polymerized hemoglobin from unpolymerized hemoglobin on hydroxyapatite using HPLC
SK134398A3 (en) * 1996-03-28 2001-01-18 Northfield Lab Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same
US5890852A (en) * 1998-03-17 1999-04-06 Emerson Electric Company Thread cutting die and method of manufacturing same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
EP1093720A1 (en) * 1995-03-23 2001-04-25 Biopure Corporation Stable polymerized hemoglobin blood-substitute

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
описание с.26, 33. *
реферат, формула, описание. *
формула, описание. *
формула, описание. Клиническая хирургия. / Под ред. Р.КОНДЕНА и др. - М.: Практика, 1998, с.204-208; 433-434. Интенсивная терапия. Реанимация. Первая помощь. / Под ред. В.Д.МАЛЫШЕВА. - М.: Медицина, 2000, с.142). *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2452519C1 (ru) * 2011-03-25 2012-06-10 Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ компенсации глобулярного объема крови и иммуномодулирующего воздействия при трансплантации
RU2861484C1 (ru) * 2025-11-11 2026-05-05 Общество с ограниченной ответственностью "НеоГемовет" (ООО "НеоГемовет") Средство для инфузии, восстанавливающее объем циркулирующей крови при кровопотерях у животных

Also Published As

Publication number Publication date
AU2003272827B2 (en) 2009-03-19
NO20051390L (no) 2005-05-30
CA2499459A1 (en) 2004-05-06
US7291592B2 (en) 2007-11-06
AU2003272827A1 (en) 2004-05-13
RU2005113240A (ru) 2005-12-10
MXPA05003340A (es) 2005-07-05
WO2004037279A1 (en) 2004-05-06
US20040067876A1 (en) 2004-04-08
CN1703235A (zh) 2005-11-30
JP2006502231A (ja) 2006-01-19
EP1553968A4 (en) 2009-06-24
EP1553968A1 (en) 2005-07-20
ZA200502307B (en) 2005-11-30

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Effective date: 20141004