CN1703235A - 治疗大量失血患者的方法 - Google Patents

治疗大量失血患者的方法 Download PDF

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Publication number
CN1703235A
CN1703235A CNA2003801009126A CN200380100912A CN1703235A CN 1703235 A CN1703235 A CN 1703235A CN A2003801009126 A CNA2003801009126 A CN A2003801009126A CN 200380100912 A CN200380100912 A CN 200380100912A CN 1703235 A CN1703235 A CN 1703235A
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CN
China
Prior art keywords
hemoglobin
solution
molecular weight
solutions
hemoglobin solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2003801009126A
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English (en)
Chinese (zh)
Inventor
S·A·古尔德
R·E·德沃斯克
M·D·道布尔迪
G·A·希德斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NORTHFIELD LAB
Original Assignee
NORTHFIELD LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NORTHFIELD LAB filed Critical NORTHFIELD LAB
Publication of CN1703235A publication Critical patent/CN1703235A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA2003801009126A 2002-10-03 2003-10-03 治疗大量失血患者的方法 Pending CN1703235A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41593502P 2002-10-03 2002-10-03
US60/415,935 2002-10-03

Publications (1)

Publication Number Publication Date
CN1703235A true CN1703235A (zh) 2005-11-30

Family

ID=32176456

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2003801009126A Pending CN1703235A (zh) 2002-10-03 2003-10-03 治疗大量失血患者的方法

Country Status (11)

Country Link
US (1) US7291592B2 (enExample)
EP (1) EP1553968A4 (enExample)
JP (1) JP2006502231A (enExample)
CN (1) CN1703235A (enExample)
AU (1) AU2003272827B2 (enExample)
CA (1) CA2499459A1 (enExample)
MX (1) MXPA05003340A (enExample)
NO (1) NO20051390L (enExample)
RU (1) RU2325924C2 (enExample)
WO (1) WO2004037279A1 (enExample)
ZA (1) ZA200502307B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050049707A1 (en) * 2003-08-29 2005-03-03 Ferree Bret A. Cemented artificial disc replacements
EP1471821B1 (en) * 2002-01-15 2013-06-26 Board Of Regents, The University Of Texas System Compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
JP2009524436A (ja) 2006-01-24 2009-07-02 ノースフィールド ラボラトリーズ、インコーポレイテッド 重合したヘモグロビンの培地、並びに島細胞の単離及び移植におけるその使用
WO2008009634A2 (en) * 2006-07-17 2008-01-24 Novo Nordisk Health Care Ag Factor viia analogues with increased activity for treating thrombocytopenia
RU2361608C1 (ru) * 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
RU2452519C1 (ru) * 2011-03-25 2012-06-10 Государственное учреждение здравоохранения Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ компенсации глобулярного объема крови и иммуномодулирующего воздействия при трансплантации
EP3655019A4 (en) 2017-07-18 2021-04-21 Virtech Bio, Inc. BLOOD SUBSTITUTES INCLUDING HEMOGLOBIN AND METHODS OF MANUFACTURING

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5955581A (en) * 1986-11-10 1999-09-21 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US5854209A (en) 1995-03-23 1998-12-29 Biopure Corporation Method for oxygenating tissue having reduced red blood cell flow
US5084558A (en) * 1987-10-13 1992-01-28 Biopure Corporation Extra pure semi-synthetic blood substitute
ATE222926T1 (de) * 1995-03-23 2002-09-15 Biopure Corp Stabiles polymerisiertes hämoglobin- blutersatzmittel
US5895810A (en) * 1995-03-23 1999-04-20 Biopure Corporation Stable polymerized hemoglobin and use thereof
US20020065211A1 (en) * 1995-03-23 2002-05-30 Biopure Corporation Increasing function of organs having reduced red blood cell flow
US6271351B1 (en) * 1995-03-23 2001-08-07 Biopure Corporation Method for preserving a hemoglobin blood substitute
US5691452A (en) * 1995-03-23 1997-11-25 Biopure Corporation Method for preserving a hemoglobin blood substitute
US6150507A (en) * 1995-03-23 2000-11-21 Biopure Corporation Method for producing a purified hemoglobin product
US6288027B1 (en) * 1995-03-23 2001-09-11 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US5691453A (en) * 1995-06-07 1997-11-25 Biopure Corporation Separation of polymerized hemoglobin from unpolymerized hemoglobin on hydroxyapatite using HPLC
RO121089B1 (ro) * 1996-03-28 2006-12-29 Northfield Laboratories, Inc. Soluţie apoasă de hemoglobină polimerată cu glutaraldehida, procedeu de preparare şi utilizarea acesteia
US5890852A (en) * 1998-03-17 1999-04-06 Emerson Electric Company Thread cutting die and method of manufacturing same

Also Published As

Publication number Publication date
MXPA05003340A (es) 2005-07-05
US7291592B2 (en) 2007-11-06
NO20051390L (no) 2005-05-30
EP1553968A1 (en) 2005-07-20
RU2005113240A (ru) 2005-12-10
CA2499459A1 (en) 2004-05-06
RU2325924C2 (ru) 2008-06-10
EP1553968A4 (en) 2009-06-24
WO2004037279A1 (en) 2004-05-06
JP2006502231A (ja) 2006-01-19
AU2003272827B2 (en) 2009-03-19
ZA200502307B (en) 2005-11-30
AU2003272827A1 (en) 2004-05-13
US20040067876A1 (en) 2004-04-08

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