AU2003227522A1 - 3-substituted quinuclidines and their use - Google Patents

3-substituted quinuclidines and their use Download PDF

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Publication number
AU2003227522A1
AU2003227522A1 AU2003227522A AU2003227522A AU2003227522A1 AU 2003227522 A1 AU2003227522 A1 AU 2003227522A1 AU 2003227522 A AU2003227522 A AU 2003227522A AU 2003227522 A AU2003227522 A AU 2003227522A AU 2003227522 A1 AU2003227522 A1 AU 2003227522A1
Authority
AU
Australia
Prior art keywords
alkyl
quinuclidine
independently
amino
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003227522A
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English (en)
Inventor
Philip K. Ahring
Tino Dyhring Jorgensen
Elsebet Ostergaard Nielsen
Gunnar M. Olsen
Dan Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of AU2003227522A1 publication Critical patent/AU2003227522A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nutrition Science (AREA)
  • Obesity (AREA)
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  • Dermatology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
AU2003227522A 2002-05-30 2003-05-27 3-substituted quinuclidines and their use Abandoned AU2003227522A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200200834 2002-05-30
DKPA200200834 2002-05-30
PCT/DK2003/000354 WO2003101987A1 (en) 2002-05-30 2003-05-27 3-substituted quinuclidines and their use

Publications (1)

Publication Number Publication Date
AU2003227522A1 true AU2003227522A1 (en) 2003-12-19

Family

ID=29594980

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003227522A Abandoned AU2003227522A1 (en) 2002-05-30 2003-05-27 3-substituted quinuclidines and their use

Country Status (11)

Country Link
US (2) US7332507B2 (https=)
EP (1) EP1513839B1 (https=)
JP (1) JP2005530814A (https=)
CN (1) CN1656093A (https=)
AT (1) ATE334129T1 (https=)
AU (1) AU2003227522A1 (https=)
CA (1) CA2482639A1 (https=)
DE (1) DE60307102T2 (https=)
MX (1) MXPA04011858A (https=)
NZ (1) NZ536197A (https=)
WO (1) WO2003101987A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05003317A (es) 2002-09-25 2005-07-05 Memory Pharm Corp Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos.
RU2389729C2 (ru) 2003-12-22 2010-05-20 Мемори Фармасьютиклз Корпорейшн 1н-индазолы, 1, 2-бензизоксазолы и 1, 2-бензизотиазолы, их получение и применение
EP1735306A2 (en) 2004-03-25 2006-12-27 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
CA2567977A1 (en) 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
NZ551712A (en) 2004-05-07 2010-07-30 Memory Pharm Corp 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparations and uses thereof
AR050253A1 (es) 2004-06-24 2006-10-11 Smithkline Beecham Corp Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento
CA2591817A1 (en) 2004-12-22 2006-06-29 Memory Pharmaceuticals Corporation Nicotinic alpha-7 receptor ligands and preparation and uses thereof
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
WO2010102968A1 (en) 2009-03-10 2010-09-16 Glaxo Group Limited Indole derivatives as ikk2 inhibitors
CN110845491B (zh) * 2018-08-21 2022-05-13 鲁南制药集团股份有限公司 一种异丙托溴铵晶体
CN110845492B (zh) * 2018-08-21 2022-05-13 鲁南制药集团股份有限公司 一种异丙托溴铵一水合物
CN113121522A (zh) * 2019-12-30 2021-07-16 武汉先路医药科技股份有限公司 一种异丙托溴铵晶体及其制备方法
CN116785286B (zh) * 2020-10-10 2026-02-17 远大医学营养科学(武汉)有限公司 戊乙奎醚在治疗或预防视力损伤性眼部疾病中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009565A1 (de) * 1990-03-24 1991-09-26 Merck Patent Gmbh Indolderivate
SE9201478D0 (sv) 1992-05-11 1992-05-11 Kabi Pharmacia Ab Heteroaromatic quinuclidinenes, their use and preparation
SE9904176D0 (sv) 1999-11-18 1999-11-18 Astra Ab New use
DE10045112A1 (de) 2000-09-11 2002-03-21 Merck Patent Gmbh Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
KR100823908B1 (ko) * 2000-10-20 2008-04-21 바이오비트럼 에이비(피유비엘) 2-, 3-, 4-, 또는 5-치환-ｎ1-(벤젠술포닐)인돌 및 이의치료 용도
ATE385497T1 (de) * 2000-12-01 2008-02-15 Neurosearch As 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten
DE10121215A1 (de) * 2001-04-30 2002-10-31 Merck Patent Gmbh Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden
DE10121217A1 (de) * 2001-04-30 2002-10-31 Merck Patent Gmbh 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden

Also Published As

Publication number Publication date
US7332507B2 (en) 2008-02-19
MXPA04011858A (es) 2005-03-31
WO2003101987A1 (en) 2003-12-11
ATE334129T1 (de) 2006-08-15
DE60307102D1 (de) 2006-09-07
US20080132704A1 (en) 2008-06-05
CN1656093A (zh) 2005-08-17
DE60307102T2 (de) 2006-12-07
US20050176756A1 (en) 2005-08-11
EP1513839A1 (en) 2005-03-16
JP2005530814A (ja) 2005-10-13
CA2482639A1 (en) 2003-12-11
EP1513839B1 (en) 2006-07-26
NZ536197A (en) 2006-08-31

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