AU2003219922B2 - Compositions for delivery of therapeutics and other materials, and methods of making and using the same - Google Patents
Compositions for delivery of therapeutics and other materials, and methods of making and using the same Download PDFInfo
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- AU2003219922B2 AU2003219922B2 AU2003219922A AU2003219922A AU2003219922B2 AU 2003219922 B2 AU2003219922 B2 AU 2003219922B2 AU 2003219922 A AU2003219922 A AU 2003219922A AU 2003219922 A AU2003219922 A AU 2003219922A AU 2003219922 B2 AU2003219922 B2 AU 2003219922B2
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- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 description 1
- TULWUZJYDBGXMY-UHFFFAOYSA-N tellurophene Chemical compound [Te]1C=CC=C1 TULWUZJYDBGXMY-UHFFFAOYSA-N 0.000 description 1
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- 229960003604 testosterone Drugs 0.000 description 1
- 238000011285 therapeutic regimen Methods 0.000 description 1
- 238000002207 thermal evaporation Methods 0.000 description 1
- GVIJJXMXTUZIOD-UHFFFAOYSA-N thianthrene Chemical compound C1=CC=C2SC3=CC=CC=C3SC2=C1 GVIJJXMXTUZIOD-UHFFFAOYSA-N 0.000 description 1
- 150000003557 thiazoles Chemical class 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
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- 229950006389 thiodiglycol Drugs 0.000 description 1
- 125000005323 thioketone group Chemical group 0.000 description 1
- 150000007944 thiolates Chemical group 0.000 description 1
- QERYCTSHXKAMIS-UHFFFAOYSA-N thiophene-2-carboxylic acid Chemical compound OC(=O)C1=CC=CS1 QERYCTSHXKAMIS-UHFFFAOYSA-N 0.000 description 1
- 150000003577 thiophenes Chemical class 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
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- 238000004448 titration Methods 0.000 description 1
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- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
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- 150000003852 triazoles Chemical class 0.000 description 1
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 description 1
- TUQOTMZNTHZOKS-UHFFFAOYSA-N tributylphosphine Chemical compound CCCCP(CCCC)CCCC TUQOTMZNTHZOKS-UHFFFAOYSA-N 0.000 description 1
- DQWPFSLDHJDLRL-UHFFFAOYSA-N triethyl phosphate Chemical compound CCOP(=O)(OCC)OCC DQWPFSLDHJDLRL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromonomer-Based Addition Polymer (AREA)
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| US36035002P | 2002-02-27 | 2002-02-27 | |
| US60/360,350 | 2002-02-27 | ||
| PCT/US2003/005937 WO2003072143A1 (en) | 2002-02-27 | 2003-02-27 | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
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| AU2003219922A1 AU2003219922A1 (en) | 2003-09-09 |
| AU2003219922B2 true AU2003219922B2 (en) | 2009-09-10 |
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| AU2003219922A Expired AU2003219922B2 (en) | 2002-02-27 | 2003-02-27 | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7138105B2 (enExample) |
| EP (1) | EP1478406B1 (enExample) |
| JP (1) | JP2005524657A (enExample) |
| AT (1) | ATE494010T1 (enExample) |
| AU (1) | AU2003219922B2 (enExample) |
| CA (1) | CA2476589C (enExample) |
| DE (1) | DE60335608D1 (enExample) |
| WO (1) | WO2003072143A1 (enExample) |
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| CN1649628A (zh) * | 2002-02-26 | 2005-08-03 | 天藤制药株式会社 | 向脂质体中包封金属络合物的方法 |
| US20050260259A1 (en) * | 2004-04-23 | 2005-11-24 | Bolotin Elijah M | Compositions for treatment with glucagon-like peptide, and methods of making and using the same |
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- 2003-02-27 WO PCT/US2003/005937 patent/WO2003072143A1/en not_active Ceased
- 2003-02-27 AU AU2003219922A patent/AU2003219922B2/en not_active Expired
- 2003-02-27 US US10/378,100 patent/US7138105B2/en not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| US7790140B2 (en) | 2010-09-07 |
| JP2005524657A (ja) | 2005-08-18 |
| US7138105B2 (en) | 2006-11-21 |
| AU2003219922A1 (en) | 2003-09-09 |
| CA2476589C (en) | 2014-02-25 |
| US20060239924A1 (en) | 2006-10-26 |
| ATE494010T1 (de) | 2011-01-15 |
| US20030224974A1 (en) | 2003-12-04 |
| DE60335608D1 (de) | 2011-02-17 |
| WO2003072143A1 (en) | 2003-09-04 |
| EP1478406A4 (en) | 2006-01-11 |
| EP1478406A1 (en) | 2004-11-24 |
| WO2003072143A9 (en) | 2004-03-04 |
| CA2476589A1 (en) | 2003-09-04 |
| EP1478406B1 (en) | 2011-01-05 |
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