AU2003218162B2 - Mutants of the P4 protein of nontypable haemophilus influenzae with reduced enzymatic activity - Google Patents
Mutants of the P4 protein of nontypable haemophilus influenzae with reduced enzymatic activity Download PDFInfo
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- AU2003218162B2 AU2003218162B2 AU2003218162A AU2003218162A AU2003218162B2 AU 2003218162 B2 AU2003218162 B2 AU 2003218162B2 AU 2003218162 A AU2003218162 A AU 2003218162A AU 2003218162 A AU2003218162 A AU 2003218162A AU 2003218162 B2 AU2003218162 B2 AU 2003218162B2
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- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1242—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36468802P | 2002-03-15 | 2002-03-15 | |
| US60/364,688 | 2002-03-15 | ||
| PCT/US2003/007895 WO2003078453A1 (en) | 2002-03-15 | 2003-03-13 | Mutants of the p4 protein of nontypable haemophilus influenzae with reduced enzymatic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003218162A1 AU2003218162A1 (en) | 2003-09-29 |
| AU2003218162B2 true AU2003218162B2 (en) | 2009-10-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003218162A Ceased AU2003218162B2 (en) | 2002-03-15 | 2003-03-13 | Mutants of the P4 protein of nontypable haemophilus influenzae with reduced enzymatic activity |
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| Country | Link |
|---|---|
| US (2) | US7615229B2 (enExample) |
| EP (1) | EP1490395A4 (enExample) |
| JP (1) | JP2005532789A (enExample) |
| KR (1) | KR100981471B1 (enExample) |
| CN (1) | CN100593544C (enExample) |
| AU (1) | AU2003218162B2 (enExample) |
| BR (1) | BR0308441A (enExample) |
| CA (1) | CA2479118A1 (enExample) |
| IL (1) | IL163988A0 (enExample) |
| MX (1) | MXPA04008890A (enExample) |
| NZ (1) | NZ535754A (enExample) |
| WO (1) | WO2003078453A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012203017B2 (en) * | 2003-12-23 | 2014-10-09 | Nationwide Children's Hospital, Inc. | Haemophilus Influenzae Type IV Pili |
| ATE557033T1 (de) * | 2003-12-23 | 2012-05-15 | Nationwide Children S Hospital Inc | Pili von haemophilus influenzae typ iv |
| EP2425856A1 (en) | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| KR101359953B1 (ko) * | 2005-06-27 | 2014-02-21 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
| JP4996934B2 (ja) * | 2007-02-05 | 2012-08-08 | 独立行政法人農業・食品産業技術総合研究機構 | 組換え型リゾチームの製造法 |
| JP2014516028A (ja) * | 2011-05-11 | 2014-07-07 | リースベック ヘルスケア スウェーデン アクティエボラーグ | ラミニン及びビトロネクチン結合特性を有するタンパク質ｆ−新規インフルエンザ菌付着因子 |
| WO2020081548A1 (en) * | 2018-10-15 | 2020-04-23 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Vaccine polypeptide compositions and methods |
| WO2022056195A1 (en) * | 2020-09-10 | 2022-03-17 | The Rochester General Hospital | Haemophilus infuluenzae vaccine and methods of use |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990010458A1 (en) * | 1989-03-09 | 1990-09-20 | Praxis Biologics, Inc. | Vaccines for nontypable haemophilus influenzae |
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| US518540A (en) * | 1894-04-17 | Electric-railway conduit | ||
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| US4599197A (en) | 1982-12-22 | 1986-07-08 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4518526A (en) | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4542104A (en) | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
| US5078996A (en) | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
| US4734362A (en) | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
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2003
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- 2003-03-13 CA CA002479118A patent/CA2479118A1/en not_active Abandoned
- 2003-03-13 CN CN03809166A patent/CN100593544C/zh not_active Expired - Fee Related
- 2003-03-13 BR BR0308441-8A patent/BR0308441A/pt not_active Application Discontinuation
- 2003-03-13 AU AU2003218162A patent/AU2003218162B2/en not_active Ceased
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- 2003-03-13 WO PCT/US2003/007895 patent/WO2003078453A1/en not_active Ceased
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2008
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990010458A1 (en) * | 1989-03-09 | 1990-09-20 | Praxis Biologics, Inc. | Vaccines for nontypable haemophilus influenzae |
Non-Patent Citations (1)
| Title |
|---|
| Reilly et al. FEBS, 2001, vol. 494, no. 1-2, pp. 19-23. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2479118A1 (en) | 2003-09-25 |
| IL163988A0 (en) | 2005-12-18 |
| CN1653084A (zh) | 2005-08-10 |
| KR20050016307A (ko) | 2005-02-21 |
| US20090148465A1 (en) | 2009-06-11 |
| CN100593544C (zh) | 2010-03-10 |
| JP2005532789A (ja) | 2005-11-04 |
| EP1490395A1 (en) | 2004-12-29 |
| EP1490395A4 (en) | 2006-06-21 |
| MXPA04008890A (es) | 2005-10-18 |
| BR0308441A (pt) | 2005-01-18 |
| AU2003218162A1 (en) | 2003-09-29 |
| US7666626B2 (en) | 2010-02-23 |
| WO2003078453A1 (en) | 2003-09-25 |
| US20050249746A1 (en) | 2005-11-10 |
| KR100981471B1 (ko) | 2010-09-10 |
| US7615229B2 (en) | 2009-11-10 |
| NZ535754A (en) | 2007-01-26 |
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