AU2002365506B2 - Benzothiazole derivatives - Google Patents
Benzothiazole derivatives Download PDFInfo
- Publication number
- AU2002365506B2 AU2002365506B2 AU2002365506A AU2002365506A AU2002365506B2 AU 2002365506 B2 AU2002365506 B2 AU 2002365506B2 AU 2002365506 A AU2002365506 A AU 2002365506A AU 2002365506 A AU2002365506 A AU 2002365506A AU 2002365506 B2 AU2002365506 B2 AU 2002365506B2
- Authority
- AU
- Australia
- Prior art keywords
- methyl
- lower alkyl
- methoxy
- morpholin
- benzamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title description 3
- 150000001875 compounds Chemical class 0.000 claims description 90
- 125000000217 alkyl group Chemical group 0.000 claims description 36
- 150000003839 salts Chemical class 0.000 claims description 22
- -1 methoxyacetyl-methyl-amino Chemical group 0.000 claims description 18
- 229910052739 hydrogen Inorganic materials 0.000 claims description 14
- 239000001257 hydrogen Substances 0.000 claims description 14
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 14
- 108050000203 Adenosine receptors Proteins 0.000 claims description 13
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- SZFSIZPBUFZDQQ-UHFFFAOYSA-N 4-[(cyclopropanecarbonylamino)methyl]-n-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)benzamide Chemical compound C1=2SC(NC(=O)C=3C=CC(CNC(=O)C4CC4)=CC=3)=NC=2C(OC)=CC=C1N1CCOCC1 SZFSIZPBUFZDQQ-UHFFFAOYSA-N 0.000 claims description 2
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Classifications
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- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01128338 | 2001-11-29 | ||
| EP01128338.9 | 2001-11-29 | ||
| PCT/EP2002/013046 WO2003045386A1 (en) | 2001-11-29 | 2002-11-21 | Benzothiazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002365506A1 AU2002365506A1 (en) | 2003-06-10 |
| AU2002365506B2 true AU2002365506B2 (en) | 2006-08-10 |
Family
ID=8179392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002365506A Ceased AU2002365506B2 (en) | 2001-11-29 | 2002-11-21 | Benzothiazole derivatives |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6624163B2 (enExample) |
| EP (1) | EP1450797B1 (enExample) |
| JP (1) | JP4146799B2 (enExample) |
| KR (1) | KR100581704B1 (enExample) |
| CN (1) | CN1304383C (enExample) |
| AR (1) | AR037457A1 (enExample) |
| AT (1) | ATE330603T1 (enExample) |
| AU (1) | AU2002365506B2 (enExample) |
| BR (1) | BR0214488A (enExample) |
| CA (1) | CA2468311C (enExample) |
| DE (1) | DE60212694T2 (enExample) |
| ES (1) | ES2266608T3 (enExample) |
| MX (1) | MXPA04005077A (enExample) |
| PA (1) | PA8558701A1 (enExample) |
| PE (1) | PE20030821A1 (enExample) |
| PL (1) | PL373947A1 (enExample) |
| RU (1) | RU2301232C2 (enExample) |
| TW (1) | TW200408395A (enExample) |
| UY (1) | UY27559A1 (enExample) |
| WO (1) | WO2003045386A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE390922T1 (de) * | 2003-06-20 | 2008-04-15 | Hoffmann La Roche | 2-aminobenzothiazole als cb1 rezeptor inverse agonisten |
| KR20060058132A (ko) * | 2003-09-19 | 2006-05-29 | 에프. 호프만-라 로슈 아게 | 아데노신 수용체 리간드로서의 싸이아졸로피리딘 유도체 |
| TW200524887A (en) * | 2003-10-27 | 2005-08-01 | Lundbeck & Co As H | N-thiazol-2-yl-benzamide derivatives |
| EP1677791A4 (en) | 2003-10-31 | 2007-08-15 | Takeda Pharmaceutical | NITROGENIC CONDENSED HETEROCYCLIC COMPOUNDS |
| DE602004025508D1 (de) * | 2003-12-23 | 2010-03-25 | Serodus As | Modulatoren von peripheren 5-ht-rezeptoren |
| JP2008506735A (ja) * | 2004-07-22 | 2008-03-06 | エフ．ホフマン−ラ ロシュ アーゲー | 置換されているベンゾチアゾール類 |
| CN1989139B (zh) * | 2004-07-22 | 2010-05-12 | 弗·哈夫曼-拉罗切有限公司 | 苯并噻唑衍生物 |
| AU2005287729A1 (en) | 2004-09-22 | 2006-03-30 | H. Lundbeck A/S | 2-acylaminothiazole derivatives |
| US7674912B2 (en) | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
| CN111205244B (zh) * | 2018-11-22 | 2023-08-18 | 上海科技大学 | 噻唑并环类化合物、其制备方法、中间体和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0113219B1 (en) | 1982-12-21 | 1987-11-19 | Johnsen & Jorgensen (Plastics) Limited | Dispensing container |
| FI91859C (fi) | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| GB8717068D0 (en) * | 1987-07-20 | 1987-08-26 | Fujisawa Pharmaceutical Co | Nitric ester derivative |
| IL90337A0 (en) * | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
| DK0604657T3 (da) * | 1992-05-21 | 2000-04-17 | Otsuka Pharma Co Ltd | Phosphonsyrediesterderivat |
| CA2413086C (en) | 2000-06-21 | 2011-06-28 | Alexander Alanine | Benzothiazole derivatives |
-
2002
- 2002-11-15 US US10/295,500 patent/US6624163B2/en not_active Expired - Fee Related
- 2002-11-21 CN CNB028236939A patent/CN1304383C/zh not_active Expired - Fee Related
- 2002-11-21 AU AU2002365506A patent/AU2002365506B2/en not_active Ceased
- 2002-11-21 EP EP02790418A patent/EP1450797B1/en not_active Expired - Lifetime
- 2002-11-21 ES ES02790418T patent/ES2266608T3/es not_active Expired - Lifetime
- 2002-11-21 CA CA2468311A patent/CA2468311C/en not_active Expired - Fee Related
- 2002-11-21 BR BR0214488-3A patent/BR0214488A/pt not_active Application Discontinuation
- 2002-11-21 WO PCT/EP2002/013046 patent/WO2003045386A1/en not_active Ceased
- 2002-11-21 PL PL02373947A patent/PL373947A1/xx not_active Application Discontinuation
- 2002-11-21 AT AT02790418T patent/ATE330603T1/de active
- 2002-11-21 KR KR1020047007915A patent/KR100581704B1/ko not_active Expired - Fee Related
- 2002-11-21 RU RU2004119985/04A patent/RU2301232C2/ru not_active IP Right Cessation
- 2002-11-21 MX MXPA04005077A patent/MXPA04005077A/es active IP Right Grant
- 2002-11-21 JP JP2003546888A patent/JP4146799B2/ja not_active Expired - Fee Related
- 2002-11-21 DE DE60212694T patent/DE60212694T2/de not_active Expired - Lifetime
- 2002-11-25 TW TW091134237A patent/TW200408395A/zh unknown
- 2002-11-25 PE PE2002001131A patent/PE20030821A1/es not_active Application Discontinuation
- 2002-11-26 PA PA20028558701A patent/PA8558701A1/es unknown
- 2002-11-28 UY UY27559A patent/UY27559A1/es not_active Application Discontinuation
- 2002-11-28 AR ARP020104580A patent/AR037457A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100581704B1 (ko) | 2006-05-22 |
| AR037457A1 (es) | 2004-11-10 |
| CA2468311C (en) | 2011-03-15 |
| BR0214488A (pt) | 2004-10-19 |
| CN1596112A (zh) | 2005-03-16 |
| DE60212694T2 (de) | 2007-06-28 |
| AU2002365506A1 (en) | 2003-06-10 |
| ES2266608T3 (es) | 2007-03-01 |
| EP1450797B1 (en) | 2006-06-21 |
| US20030134855A1 (en) | 2003-07-17 |
| TW200408395A (en) | 2004-06-01 |
| CA2468311A1 (en) | 2003-06-05 |
| JP4146799B2 (ja) | 2008-09-10 |
| PA8558701A1 (es) | 2003-09-05 |
| RU2301232C2 (ru) | 2007-06-20 |
| RU2004119985A (ru) | 2006-01-10 |
| MXPA04005077A (es) | 2004-08-19 |
| PE20030821A1 (es) | 2003-10-04 |
| US6624163B2 (en) | 2003-09-23 |
| PL373947A1 (en) | 2005-09-19 |
| EP1450797A1 (en) | 2004-09-01 |
| JP2005518363A (ja) | 2005-06-23 |
| WO2003045386A1 (en) | 2003-06-05 |
| CN1304383C (zh) | 2007-03-14 |
| KR20040062967A (ko) | 2004-07-09 |
| DE60212694D1 (de) | 2006-08-03 |
| ATE330603T1 (de) | 2006-07-15 |
| UY27559A1 (es) | 2003-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |