AU2002350672A1 - Detergent and cosmetic compositions comprising capryloyl glutamate salts and/or capryloyl hydrolysate salts of wheat and/or rice protein - Google Patents
Detergent and cosmetic compositions comprising capryloyl glutamate salts and/or capryloyl hydrolysate salts of wheat and/or rice proteinInfo
- Publication number
- AU2002350672A1 AU2002350672A1 AU2002350672A AU2002350672A AU2002350672A1 AU 2002350672 A1 AU2002350672 A1 AU 2002350672A1 AU 2002350672 A AU2002350672 A AU 2002350672A AU 2002350672 A AU2002350672 A AU 2002350672A AU 2002350672 A1 AU2002350672 A1 AU 2002350672A1
- Authority
- AU
- Australia
- Prior art keywords
- salts
- self
- acid
- preservative
- capryloyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims description 64
- 150000003839 salts Chemical class 0.000 title claims description 48
- 239000002537 cosmetic Substances 0.000 title claims description 27
- 239000003599 detergent Substances 0.000 title claims description 24
- 239000000413 hydrolysate Substances 0.000 title claims description 20
- 102000004169 proteins and genes Human genes 0.000 title claims description 18
- 108090000623 proteins and genes Proteins 0.000 title claims description 18
- 241000209140 Triticum Species 0.000 title claims description 16
- 235000021307 Triticum Nutrition 0.000 title claims description 16
- 235000007164 Oryza sativa Nutrition 0.000 title claims description 15
- 235000009566 rice Nutrition 0.000 title claims description 15
- MKLBZEFCSOAOQB-JTQLQIEISA-N (4S)-4-amino-5-octanoyloxy-5-oxopentanoic acid Chemical class CCCCCCCC(=O)OC(=O)[C@@H](N)CCC(O)=O MKLBZEFCSOAOQB-JTQLQIEISA-N 0.000 title claims description 13
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 title claims description 11
- 240000007594 Oryza sativa Species 0.000 title 1
- 235000002639 sodium chloride Nutrition 0.000 claims description 56
- 239000003755 preservative agent Substances 0.000 claims description 40
- 239000011149 active material Substances 0.000 claims description 34
- 230000000887 hydrating effect Effects 0.000 claims description 26
- -1 alkaline earth metal cations Chemical class 0.000 claims description 25
- 239000003795 chemical substances by application Substances 0.000 claims description 16
- 208000001840 Dandruff Diseases 0.000 claims description 14
- 241000209094 Oryza Species 0.000 claims description 14
- 150000001768 cations Chemical class 0.000 claims description 13
- 210000002374 sebum Anatomy 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 11
- 230000001105 regulatory effect Effects 0.000 claims description 11
- 230000036571 hydration Effects 0.000 claims description 8
- 238000006703 hydration reaction Methods 0.000 claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 7
- 238000009472 formulation Methods 0.000 claims description 7
- 230000002335 preservative effect Effects 0.000 claims description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 6
- 150000001412 amines Chemical class 0.000 claims description 6
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 5
- 235000013877 carbamide Nutrition 0.000 claims description 5
- CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 claims description 4
- 239000004875 Anti-Odour Agent Substances 0.000 claims description 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 4
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 4
- 239000000460 chlorine Substances 0.000 claims description 4
- 229910052801 chlorine Inorganic materials 0.000 claims description 4
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 claims description 4
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 claims description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 4
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 claims description 4
- ARIWANIATODDMH-UHFFFAOYSA-N rac-1-monolauroylglycerol Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 229960004418 trolamine Drugs 0.000 claims description 4
- WEYVVCKOOFYHRW-UHFFFAOYSA-N usnic acid Chemical compound CC12C(=O)C(C(=O)C)=C(O)C=C1OC1=C2C(O)=C(C)C(O)=C1C(C)=O WEYVVCKOOFYHRW-UHFFFAOYSA-N 0.000 claims description 4
- 239000004202 carbamide Substances 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 239000004094 surface-active agent Substances 0.000 claims description 3
- VUWCWMOCWKCZTA-UHFFFAOYSA-N 1,2-thiazol-4-one Chemical class O=C1CSN=C1 VUWCWMOCWKCZTA-UHFFFAOYSA-N 0.000 claims description 2
- HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical compound CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 claims description 2
- VSHIRTNKIXRXMI-UHFFFAOYSA-N 2,2-dimethyl-1,3-oxazolidine Chemical compound CC1(C)NCCO1 VSHIRTNKIXRXMI-UHFFFAOYSA-N 0.000 claims description 2
- IOAOAKDONABGPZ-UHFFFAOYSA-N 2-amino-2-ethylpropane-1,3-diol Chemical compound CCC(N)(CO)CO IOAOAKDONABGPZ-UHFFFAOYSA-N 0.000 claims description 2
- UXFQFBNBSPQBJW-UHFFFAOYSA-N 2-amino-2-methylpropane-1,3-diol Chemical compound OCC(N)(C)CO UXFQFBNBSPQBJW-UHFFFAOYSA-N 0.000 claims description 2
- JCBPETKZIGVZRE-UHFFFAOYSA-N 2-aminobutan-1-ol Chemical compound CCC(N)CO JCBPETKZIGVZRE-UHFFFAOYSA-N 0.000 claims description 2
- NCKMMSIFQUPKCK-UHFFFAOYSA-N 2-benzyl-4-chlorophenol Chemical compound OC1=CC=C(Cl)C=C1CC1=CC=CC=C1 NCKMMSIFQUPKCK-UHFFFAOYSA-N 0.000 claims description 2
- DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 claims description 2
- YFNXWBPNBVLTMB-UHFFFAOYSA-N 2-bromo-2-nitro-1,4-dioxane Chemical compound [O-][N+](=O)C1(Br)COCCO1 YFNXWBPNBVLTMB-UHFFFAOYSA-N 0.000 claims description 2
- QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 claims description 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 2
- FHYNZKLNCPUNEU-UHFFFAOYSA-N 4-[(3,4-dihydroxyphenyl)methyl]-3-[(4-hydroxyphenyl)methyl]oxolan-2-one Chemical compound C1=CC(O)=CC=C1CC1C(=O)OCC1CC1=CC=C(O)C(O)=C1 FHYNZKLNCPUNEU-UHFFFAOYSA-N 0.000 claims description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 2
- 239000004475 Arginine Substances 0.000 claims description 2
- 239000005711 Benzoic acid Substances 0.000 claims description 2
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 claims description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 2
- 229920001287 Chondroitin sulfate Polymers 0.000 claims description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- MDNWOSOZYLHTCG-UHFFFAOYSA-N Dichlorophen Chemical compound OC1=CC=C(Cl)C=C1CC1=CC(Cl)=CC=C1O MDNWOSOZYLHTCG-UHFFFAOYSA-N 0.000 claims description 2
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- 239000004166 Lanolin Substances 0.000 claims description 2
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 claims description 2
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 claims description 2
- 239000004264 Petrolatum Substances 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical class OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 claims description 2
- SLINHMUFWFWBMU-UHFFFAOYSA-N Triisopropanolamine Chemical compound CC(O)CN(CC(C)O)CC(C)O SLINHMUFWFWBMU-UHFFFAOYSA-N 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims description 2
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 2
- 239000002280 amphoteric surfactant Substances 0.000 claims description 2
- 239000012736 aqueous medium Substances 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- 150000003937 benzamidines Chemical class 0.000 claims description 2
- 235000010233 benzoic acid Nutrition 0.000 claims description 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 2
- 239000004327 boric acid Substances 0.000 claims description 2
- 235000010338 boric acid Nutrition 0.000 claims description 2
- 229960003168 bronopol Drugs 0.000 claims description 2
- 229960003260 chlorhexidine Drugs 0.000 claims description 2
- VXIVSQZSERGHQP-UHFFFAOYSA-N chloroacetamide Chemical compound NC(=O)CCl VXIVSQZSERGHQP-UHFFFAOYSA-N 0.000 claims description 2
- 229960002242 chlorocresol Drugs 0.000 claims description 2
- 229930003836 cresol Natural products 0.000 claims description 2
- 229960003887 dichlorophen Drugs 0.000 claims description 2
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims description 2
- 229940043237 diethanolamine Drugs 0.000 claims description 2
- 235000019441 ethanol Nutrition 0.000 claims description 2
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims description 2
- 238000001704 evaporation Methods 0.000 claims description 2
- 230000008020 evaporation Effects 0.000 claims description 2
- 235000019253 formic acid Nutrition 0.000 claims description 2
- 229940068939 glyceryl monolaurate Drugs 0.000 claims description 2
- 239000004312 hexamethylene tetramine Substances 0.000 claims description 2
- 235000010299 hexamethylene tetramine Nutrition 0.000 claims description 2
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 claims description 2
- 239000011630 iodine Substances 0.000 claims description 2
- 229910052740 iodine Inorganic materials 0.000 claims description 2
- 239000004310 lactic acid Substances 0.000 claims description 2
- 235000014655 lactic acid Nutrition 0.000 claims description 2
- 235000019388 lanolin Nutrition 0.000 claims description 2
- 229940039717 lanolin Drugs 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 claims description 2
- 229960004011 methenamine Drugs 0.000 claims description 2
- 239000002480 mineral oil Substances 0.000 claims description 2
- 108700019599 monomethylolglycine Proteins 0.000 claims description 2
- 229960003104 ornithine Drugs 0.000 claims description 2
- 229960005010 orotic acid Drugs 0.000 claims description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 2
- 229940066842 petrolatum Drugs 0.000 claims description 2
- 235000019271 petrolatum Nutrition 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 229960004889 salicylic acid Drugs 0.000 claims description 2
- 229940101011 sodium hydroxymethylglycinate Drugs 0.000 claims description 2
- CITBNDNUEPMTFC-UHFFFAOYSA-M sodium;2-(hydroxymethylamino)acetate Chemical compound [Na+].OCNCC([O-])=O CITBNDNUEPMTFC-UHFFFAOYSA-M 0.000 claims description 2
- ASEFUFIKYOCPIJ-UHFFFAOYSA-M sodium;2-dodecoxyethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOS([O-])(=O)=O ASEFUFIKYOCPIJ-UHFFFAOYSA-M 0.000 claims description 2
- 239000004334 sorbic acid Substances 0.000 claims description 2
- 235000010199 sorbic acid Nutrition 0.000 claims description 2
- 229940075582 sorbic acid Drugs 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 235000010356 sorbitol Nutrition 0.000 claims description 2
- 150000003672 ureas Chemical class 0.000 claims description 2
- 229940004858 usnic acid Drugs 0.000 claims description 2
- ICTZCAHDGHPRQR-UHFFFAOYSA-N usnic acid Natural products OC1=C(C)C(O)=C(C(C)=O)C2=C1C1(C)C(O)=C(C(=O)C)C(=O)C=C1O2 ICTZCAHDGHPRQR-UHFFFAOYSA-N 0.000 claims description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 2
- TYBHZVUFOINFDV-UHFFFAOYSA-N 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol Chemical compound OC1=C(Br)C=C(Cl)C=C1CC1=CC(Cl)=CC(Br)=C1O TYBHZVUFOINFDV-UHFFFAOYSA-N 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 229920001090 Polyaminopropyl biguanide Polymers 0.000 claims 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 1
- 239000004141 Sodium laurylsulphate Substances 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 125000002091 cationic group Chemical group 0.000 claims 1
- KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 claims 1
- 125000006266 dimethyl hydroxy methyl group Chemical group [H]OC(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 claims 1
- 229960004068 hexachlorophene Drugs 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 229940093424 polyaminopropyl biguanide Drugs 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 235000019260 propionic acid Nutrition 0.000 claims 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 24
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 16
- 235000018102 proteins Nutrition 0.000 description 16
- 239000011734 sodium Substances 0.000 description 10
- 229910052708 sodium Inorganic materials 0.000 description 10
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 9
- 238000012360 testing method Methods 0.000 description 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 8
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- 125000000217 alkyl group Chemical class 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 229960003237 betaine Drugs 0.000 description 5
- BCGXTKYOBWQPCN-PPHPATTJSA-M sodium;(4s)-5-hydroxy-4-(octanoylamino)-5-oxopentanoate Chemical compound [H+].[Na+].CCCCCCCC(=O)N[C@H](C([O-])=O)CCC([O-])=O BCGXTKYOBWQPCN-PPHPATTJSA-M 0.000 description 5
- 230000004083 survival effect Effects 0.000 description 5
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- 150000001408 amides Chemical class 0.000 description 4
- 238000011081 inoculation Methods 0.000 description 4
- 239000002085 irritant Substances 0.000 description 4
- 231100000021 irritant Toxicity 0.000 description 4
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- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical class CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
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- 241000233866 Fungi Species 0.000 description 3
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- 108010009736 Protein Hydrolysates Proteins 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 3
- 238000003436 Schotten-Baumann reaction Methods 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 229910021529 ammonia Inorganic materials 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 235000013922 glutamic acid Nutrition 0.000 description 3
- 239000004220 glutamic acid Substances 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 239000002054 inoculum Substances 0.000 description 3
- 239000011777 magnesium Substances 0.000 description 3
- 229910052749 magnesium Inorganic materials 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- CNDHHGUSRIZDSL-UHFFFAOYSA-N 1-chlorooctane Chemical compound CCCCCCCCCl CNDHHGUSRIZDSL-UHFFFAOYSA-N 0.000 description 2
- MCNJOIMMYWLFBA-UHFFFAOYSA-N 2-dodecoxy-2-oxoethanesulfonic acid;sodium Chemical compound [Na].CCCCCCCCCCCCOC(=O)CS(O)(=O)=O MCNJOIMMYWLFBA-UHFFFAOYSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 239000003945 anionic surfactant Substances 0.000 description 2
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Description
DETERGENT AND COSMETIC COMPOSITIONS COMPRISING CAPRYLOYL GLϋTAMATE SALTS AND/ ODER CAPRYLOYL HYDROLYSATE SALTS OF WHEAT AND/OR RICE PROTEIN
The present invention relates to a detergent or cosmetic composition provided with sebum regulating, anti-dandruff and/or anti-odour properties and simultaneously provided with hydrating and self-preservative properties.
In the formulation of cosmetic or detergent compositions with sebum regulating, anti-dandruff and/or anti-odour properties the use of derivatives of caprylic acid is known. However, the problem with the derivatives commonly utilised is often that of excessively delipidising the corneal layer of the skin by acting as a solvent of the functional lipids contained in it and simultaneously removing the water-soluble substances from it . All this causes excessive drying of the skin and fragility of the hair, which problems are commonly resolved by adding suitable hydrating agents to the formulations. In the formulation of cosmetic or detergent compositions in general it is moreover necessary to add self- preservative agents which have the function of preserving the composition from pollution by bacteria and other microorganisms such as, for example, fungi and yeasts, which can be the cause of infections in man. However, the disadvantage associated with the use of self-preservative agents is that in order to be efficacious they must often be utilised at irritant concentrations or at concentrations at which they sensitise the tissue with which they come into contact.
The present invention therefore has the object of providing a detergent or cosmetic composition provided with the above
indicated functional properties (that is to say, sebum regulating, anti-dandruff and/or anti-odour) which does not have the above-mentioned disadvantages.
This object has been achieved by the present inventors, who have identified various derivatives of caprylic acid which, when formulated in detergent or cosmetic compositions, are not only able to perform the sebum regulating, anti-dandruff and/or anti-odoμr activity, but are simultaneously able to confer on the said composition hydrating and self- preservative properties .
These derivatives are salts of capryloyl glutamate and capryloyl hydrolysate of rice and/or wheat protein.
The salts of capryloyl glutamate can be obtained by the Schotten-Baumann reaction by making the amino group of the glutamic acid react with capryloyl chloride in a basic environment, according to the following reaction:
COOH COOH
I OH" I
H2N- CH + CH3-(CH2)6-C0C1 ~> CH3- (CH2) 6-CO-CH
I I
CH2- CH2-COOH CH2
CH2
COOH
In the same way the salts of capryloyl hydrolysate can be obtained by means of the Schotten-Baumann reaction by making the amino group present in the hydrolysate react with
capryloyl chloride in a basic environment according to the following reaction:
CH3-(CH2)6-C0-C1 +RNH2 ωr > CH3- (CH2) 6-CO-NH-R,
Wherein R is the peptide residue obtainable by means of hydrolysis of wheat and/or rice proteins.
This peptide residue (or hydrolysate) is obtained by acid hydrolysis (with HC1) of gluten (wheat) and/or husks (rice) and subsequent filtration to separate the product obtained from the drogs .
As an alternative to chemical hydrolysis, an enzymatic hydrolysis can also be used, by exploiting the amylase and protease enzymes .
The product obtained from hydrolysis is a mixture of peptides having a molecular weight between 1000 and 4000 Dalton. In the ambit of the present specification this product will sometimes be indicated as "peptide residue" and other times as "hydrolysate of wheat and/or rice protein" .
During the Schotten-Baumann reaction the dissociated carboxylic groups present are neutralised by salification with a base chosen in dependence on the desired salt, for example NaOH or KOH. Alternatively, to obtain salts of a weak base such as TEA the sodium or potassium salt is brought to a pH of 2.0-3.0 with phosphoric acid to obtain the acid form and subsequently dissolved in- water and neutralised with the desired base.
In the above-described salts the dissociated carboxylic groups are preferably neutralised with cations chosen from groups which consist of: cations belonging to the groups of alkaline metals or other monovalant cations such as Cu+; cations belonging to the groups of alkaline earth metals or other bivalent cations such as Pb2+; trivalent cations such as Al3+; polyvalent cations such as Sn4+; NH4 + or amine bases chosen from triethanol amine, monoethanol amine, diethanol amine, monoisopropanol amine, tri-isopropanol amine, 2-amino butanol, amino ethylpropanediol, arginine, lisine, ornithine, amino methyl propanol, amino methyl propanediol and 2-amino- 2-hydroxymethyl-l,3-propanediol. Such neutralising cations can also be utilised in combination with one another.
A subject of the invention is therefore the use of a salt of capryloyl glutamate and/or capryloyl hydrolysate of wheat and/or rice proteins as self-preservative and hydrating agents and simultaneously sebum regulating, anti-dandruff and/or anti-odour agents in the formulation of a detergent or cosmetic composition free from other self-preservative agents and other hydrating agents, or including other self- preservative and/or hydrating agents at a non-efficacious concentration and/or insufficient to confer the desired characteristics of self-preservative and/or hydration in an analogous or similar composition free of the said compounds (composition) .
Another subject of the invention is a detergent or cosmetic composition provided with hydrating and self-preservative properties and simultaneously sebum regulating, anti-dandruff and/or anti-odour properties, such sebum regulating, anti- dandruff and/or anti-odour agents including a composition which is a salt of capryloyl glutamate and/or of capryloyl
hydrolysate of wheat and/or rice protein, the said salt further having self-preservative and hydrating effect, the said composition therefore being free from other self- preservative agents and other hydrating agents, or including other self-preservative and/or hydrating agents at non- efficacious concentrations and/or insufficient to confer the desired self-preservative and/or hydration characteristics to an analogous or similar composition free from the said salt.
The expression "analogous or similar composition free from the said salt" is intended to indicate a composition constituted by the same components in the same quantities as the composition of the invention, but which is differentiated from it by the fact that the capryloyl glutamate salt and/or capryloyl hydrolysate salt of wheat and/or rice proteins is replaced by an equal quantity of other anionic surfactant agent .
In general it can be understood that a detergent or cosmetic composition has the desired self-preservative characteristic when it responds positively to the tests for evaluation of the efficacy of the preserving power. Such tests are conducted according to the indications provided by the United States Pharmacopoeia (USP) and/or by the Cosmetic, Toiletry and Fragrance Association (CTFA) . These methods, and other similar methods, involve the inoculation of the samples with micro-organisms of different types and counting the aerobic microbes of these at different times to evaluate the survival level .
The self-preservative efficacy of the salts utilised in the present invention has been confirmed by means of challenge tests conducted on aqueous solutions of capryloyl glutamate
in the form of sodium salt, inoculated with mixed inoculants (see example 1) .
The tests, as well as confirming the self-preservative efficacy of the composition, also demonstrated that it increases with the reduction of pH. Consequently, it is preferred that the cosmetic or detergent composition according to the invention has a pH less than or equal to 5, more preferably, a pH in the range from 3.5 to 5.0.
The use of the above-indicated salts in the formulation of detergent or cosmetic compositions thus makes it possible to eliminate or in any event substantially reduce the concentration of the usual self-preservative agents the concentration of which, if present, will nevertheless be less than the threshold of irritant and/or sensitising activity.
Among the self-preservative agents commonly utilised in detergent or cosmetic compositions of the prior art, but absent from the composition according to the invention, or at most present in non-irritant or non-self-preservative concentrations are, for example, formaldehyde, chlorine, hypochlorite, compounds which release chlorine, chlorine dioxide, iodine and iodofers, phenol, cresol, chlorocresol, amphoteric compounds with self-preservative characteristics, chlorhexidine, peracetic acid and dihydroacetic acid, mercury compounds, alcohols, sorbic acid, benzoic acid, salicylic acid, boric acid, formic acid, crotonic acid and salts derived from the use, bronopol, 5-bromo-5-nitrodioxane, hexamethylene tetramine, DMDM idantoine, various inantoines such as MD idantoine, chloracetamide, ureas such as imidazolidinyl urea and diazolidinyl urea, inorganic sulphites, triclosane, parabenes, isothiazolinones, usnic
acid and its salts, chlorophene, hexachlo ophene, dichlorophene, bromocheorophene, trichlorocarbon, chloroflourocarbon, benzamidines classified as self- preservatives, amines classified as self-preservatives, dimethyloxazolidine, ethylbicyeloxazolidine, dimethylhydroxymethylpyrazole, polyaminopropylbiguamide, sodium hydroxy-methylglycinate, methyldibromoglutaronitrile, glyceryl monolaurate and their mixtures .
The non-irritant or non-self-preservative concentration varies in dependence on the compound considered, and can be easily determined by the man skilled in the art since the above-listed compounds are all known and usually utilised in cosmetics as self-preservatives.
In general it can be understood that a detergent or cosmetic composition has the desired hydrating characteristics when it is capable of obviating the symptoms and manifestations of dry skin and hair (according to the definition of "hydrating compounds" in "A Short Textbook of Cosmetology", K.F. De Polo, first edition 1998) .
The salts utilised in the present invention have such hydrating properties.
The molecules of capryloyl glutamate and capryloyl hydrolysate, once they come into contact with the skin, in fact separate into glutamates and hydrolysate on the one hand and fatty acid on the other.
Both wheat and rice hydrolysate protein and glutamic acid have hydrating properties.
In fact, the protein hydrolysate, in contact with the skin, forms a continuous protective layer over the corneal layer thereof, protecting it from external aggressions and. increasing the hydration by reduction of TEWL (Trans Epidermal Water Loss) . Moreover such protein hydrolysates are sources of amino acid, which constitutes 40% of the natural moisturising factor ( MF) . The glutamic acid on the other hand enters into a series of biological cycles contributing to the correct hydration of the skin and to maintenance of the natural cutaneous acidity thanks to the two to carboxylic groups. In fact, it constitutes 15% of the keratins and forms part of the ε (γ-glutamyl) lysine bond present in the in involucrin and keratolin proteins which constitute the cellular membrane of the corneal layer. It can be transformed into PCA, one of the components of the NMF, that is to say a set of water soluble substances responsible for the correct hydration, as well as into proline and hydroxyproline (these two amino acids are fundamental for the synthesis of collagen and elastine) . The acylglutamates, moreover, act as selective solvents for the principal component of the sebum, i.e., squalene, therefore leaving unaltered the functional lipids of the corneal layer which control the hydration.
The caprylic acid component on the other hand performs its particular action of controlling the increase of pathogenic micro-organisms, dandruff, body odours, the production of sebum and cutaneous disorders .
The use of salts ,of capryloyl glutamate and/or capryloyl hydrolysate of wheat and/or rice protein in the formulation of the detergent or cosmetic compositions according to the invention thus make it possible to eliminate or in any event
substantially reduce the addition of hydrating factors, emollients or palliatives for the skin, concentrations of which, if present, will nevertheless be less than the efficacious threshold for hydrating activity.
Among the hydrating agents commonly utilised in detergent or cosmetic compositions of the prior art, but absent from the compositions according to the invention, or at most present in non-efficacious concentrations, are, for example, glycerine, sorbitol, propyleneglycol, polyethylene glycol with molecular weight from 200 to 600, Sorbeth-30, urea, lactic acid and its salts, mucopolysaccharides such as ialuronic acid and chondroitin sulphate, ' orotic acid, lanolin, petrolatum, mineral oils, occlusive substances which hydrate the skin by preventing the evaporation of water, and their mixtures .
The concentration which is not efficacious for hydration varies in dependence on the compound considered, and can be easily determined by the man skilled in the art since the above-listed compounds are all known and commonly utilised in cosmetics as hydratants .
The detergent or cosmetic compositions according to the invention preferably include an aqueous medium, although the salts utilised can equally well be used in emulsions.
The total concentration of salts of capryloyl glutamate and/or capryloyl hydrolysate of wheat and/or rice protein in the compositions according to the invention is preferably one which is sufficient in itself to confer the desired self- preservative characteristics and hydrating action, that is such as to confer the said characteristics in combination
with other self-preservative and/or hydrating agents present in concentrations which are not sufficient per se to confer such characteristics .
This concentration lies preferably between 0.5% and 25% by weight of active substance with respect to the total composition, more preferably between 1.5% and 15% by weight of active substance. In this range of concentration, in fact, the salts present are able correctly to perform all their functions .
The detergent or cosmetic compositions according to the invention can include at least one further and separate surfactant agent chosen from anionic surfactants such as, for example, salts of alkyl sulphates and alkyl ether sulphates (for example sodium, magnesium, TEA, MEA and ammonia salts) , salts of amide/amide • ether sulphates, salts of alkyl semisulphosuccinates and alkyl sulphosuccinates, salts of alkyl ether semisulphosuccinates and alkyl ether sulphosuccinates, salts of acyl amide semisulphosuccinates and of acyl amide sulphosuccinates, salts of dodecyl benzene sulphoniσ acid, salts of alkyl/alkyl ether sulphoacetates, salts of sulphonated and/or sulphated organic molecules (for example, α-olefin sulphonates) , salts of alkyl/alkyl ether carboxylates, alkyl phosphonates, esters of phosphoric acid, salts of acyl septionates; amphoteric surfactants, such as, for example, alkyl betaine, alkyl amidopropylbetaine, oxides of amine and of amides, amphocarboxyacetates and amphocarboxydiacetates, amphocarboxypropionates and amphocarboxydipropionates; non-ionic surfactants such as, for example, various amides, ethoxylated and non-ethoxylated fatty amines, ethoxylated nonylphenol, APG (alkyl polyglucosides) , AEG (alkyl ethoxyglucosides) , esters/ethers
of fatty acids with glycerol and/or ethoxylated and non- ethoxylated sugars, various ethoxylated/propoxylated and non- ethoxylated/propoxylated esters, ethoxylated/propoxylated and non-ethoxylated/propoxylated fatty alcohols, silicone molecules; cationic surfactants containing, for example, at least one atom of quaternary nitrogen.
Some products in which the compositions of the inventions can be used are: shampoo, foam baths, foam showers, washing up liquid, liquid soaps, solid soaps, lotions, emulsions of various types, balsams, products having simultaneous detergent and conditioning effects on the skin and/or hair, oils, emollient and detergent milks, face cream and/or body cream and/or hair cream, detergents for intimate hygiene, brilliantine, permanent wave solutions, hair colouring, dentifrice, medicated cosmetics and pharmaceutical products.
The examples which follow are provided solely for the purpose of illustration and or not intended to limit in any way the scope of the invention.
EXAMPLES
Example 1: test on the self-preservative efficacy
To evaluate the self-preservative efficacy of sodium salts of capryloyl glutamate a challenge test was conducted on a cosmetic composition comprising:
Sodium lauryl ether sulphate 20E (27% a.m.) = 37%
Cocoamidopropyl betaine (30% a.m.) = 5%
Sodium capryloyl glutamate (about 1.5% a.m.) = 5%
Water = to 100% pH = 5.
Four mixed inoculations illustrated in the following table 1 (gram+ bacteria; gram- bacteria; yeasts; filamentary fungi) were prepared and each of these was inoculated with a specimen of the above-indicated composition.
Table 1
GRAM+ BACTERIA: lxlO7 Staphylococcus aureas ATCC6538
Staphylococcusepidermidis ATCC 12228
GRAM- BACTERIA: lxlO7 Eschericha coli ATCC 8739
Pseudomonas aeruginosa ATCC 9027 Enterobacter cloacae ATCC 13047 Pseudomonas putida (from cosmetics)
YEASTS: lxlO7 Candida albicans ATCC 10231
Saccharomyces cerevisiae ATCC 9763
FILAMENTARY FUNGI: 1x10s Aspergillus niger ATCC 16404
Penicillium funiculosum ATCC 9644
The challenge test consists in monitoring the survival of the inoculants over time; this survival is indicative of the self-preservative capacity of the cosmetic product during the period of use by the consumer.
In particular, survival of the inoculants was checked after 24 hours, seven days and 28 days from the inoculation. Monitoring at 24 hours represents a datum for the purpose of evaluating the rapidity of the self-preservative system, that at 7 days indicates on the other hand the degree of risk of pollution of the product, whilst the test at 28 days, as well as representing confirmation of the previously obtained data, makes it possible ' to show .up the possible formation of resistant strains.
The results obtained are illustrated in the following Table 2.
Table 2
Values obtained in the survival tests of the inoculations expressed in colony forming units per gram of product (c.f .u./g)
By successive dilutions the minimum inhibiting concentration (MIC) of an aqueous solution at pH 5 of sodium capryloyl glutamate against some micro-organisms involved in the etiology of dandruff and some skin and related diseases was calculated. The results obtained are shown in the following Table 3.
Table 3
agent involved in the etiology of dandruff and in many skin disorders b agent involved in the etiology of acne σ agent which determines pathological events above all in individuals with compromised immune defences; it is one of the principal protagonists of hospital infections.
Example 2 : Hydrating Face Cleaner without self-preservatives
Sodium capryloyl glutamate (30% active material) : 6%
Sodium cocoamphodiacetate (26% active material) : 10%
Sodium lauryl sulphoacetate (65% active material) : 1.5%
PEG-7 glyceril cocoate: 2%
Citric acid: as required to pH 5.0
NaCl : as needed
Colour and perfume: as needed
Water: to 100%
Example 3 : sebum regulating face gel
Sodium capryloyl hydrolysate of rice protein (30% active material) : 9%
Laurylmidopropyl betaine (30% active material) : 20%
Sodium cocoamphodiacetate (26% active material) : 3%
Cocoamidopropylaminooxide (30% active material) : 10%
Citric acid: as needed to pH 5.0
NaCl, colour, perfume and water: to 100%
Example 4: sports shower gel with deodorant effect
Potassium capryloyl hydrolysate of wheat protein (30% active material) : 6%
Laurylethoxysulphate of magnesium ethoxylate 2 moles (25% active material) : 15%
Laurylamidopropy1 betaine (30% active material) : 20%
PEG-7 glyceryl coccoate: 1%
Citric acid: as required to pH 4.5 NaCl, colour, perfume and water: to 100%
Example 5 : intimate detergent
Salts of triethanolamine capryloyl hydrolysate of wheat protein (30% active material) : 7%
Sodium capryloyl glutamate (30% active material) : 3%
Laurylethoxysulphate of magnesium ethoxylate 2 moles (25% active material) : 10%
Cocoamidopropyl betaine (30% active material) : 6%
Disodiumlaurylethoxysemisulphosuccinate (30% active material) : 4%
Citric acid: as need to pH 3.5 to 4.0
NaCl, colour, perfume and water: to 100%
Example 6 : anti-dandruff shampoo
Sodium capryloyl glutamate (30% active material) : 10%
Laurylethoxysulphate of sodium ethoxylate 3 moles (27% active material) : 35%
Laurylamidopropyl betaine (30% active material) : 5%
Laurylsulphate of ammonia (26% active material) : 9%
DEA coccoamide (100% active material) : 1%
Citric acid: as needed to pH 4.5
NaCl, colour, perfume and water: to 100%
Example 7 :
Potassium capryloyl hydrolysate of rice protein (30% active material) : 5%
Laurylethoxysulphate of sodium ethoxylate 3 moles (27% active material) : 30%
Potassium capryloyl glutamate (30% active material) : 3%
Laurylsulphate of tri-ethanol amine (39% active material) : 6%
Citric acid: as needed to pH 4.2
NaCl, colour, perfume and water: to 100%
Example 8 : antidandruff shampoo
Potassium capryloyl glutamate (30% active material) : 8% Lauryamidopropyl betaine (30% active material) : 10%. Laurylethoxysulphate of sodium ethoxylate 3 moles (27% active material) : 10%
Sodium lauryl sulphoacetate (65% active material) : 1% Lauryl sulphate. of ammonia (26% active material): 10% Citric acid: as needed to pH 5.0 NaCl, colour, perfume and water: to 100%
Example 8 : hand wash
Sodium capryloyl hydrolysate of wheat protein (30% active material) : 8%
Ethoxylated sodium lauryl ethoxysulphate 2 mole (27% active material) : 20%
Coccoa idopropylbetaine (30% active material) : 4%
Citric acid: as needed to pH 4.0
NaCl, colour, perfume and water: to 100%
Claims (11)
1. A detergent or cosmetic composition provided with hydrating and self-preservative properties and simultaneously sebum regulating, anti-dandruff and/or anti-odour properties, comprising as sebum regulating, anti-dandruff and/or anti- odour agent a salt of capryloyl glutamate and/or capryloyl hydrolysate of wheat and/or rice proteins, the said salts also having self-preservative and hydrating effects, the said composition thereby being free from other self-preservative agents and other hydrating agents, or comprising other self- preservative and/or hydrating agents in a non-efficacious and/or insufficient concentration to confer the desired self- preservative and/or hydration characteristics in an analogous or similar composition free from the said salts .
2. The composition according to Claim 1, wherein the said salt is selected from the group consisting of : salts with alkaline metal cations or other monovalent cations such as Cu+; salts with alkaline earth metal cations or other bivalent cations such as Pb2+; salts with trivalent cations such as Al3+; salts with polyvalent cations such as Sn4+; salts with NH4 + or with an amino base selected from tri- ethanol amine, monethanol amine, diethanol amine, monoisopropanol amine, tri-isopropanol amine, 2-amino butanol, amino ethyl propanediol, arginine, lisine, ornithine, amino methyl propanol, amino methyl propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol; and their combinations .
3. The composition according to Claim 1 or 2 further including an aqueous medium.
4. The composition according to any of Claims 1 to 3, having a pH value less than or equal to 5.
5. The composition according to any of Claims 1 to 4, wherein the said further hydrating agent is selected from the group consisting of: glycerine, sorbitol, propylene glycol, polyethylene glycol with molecular weight from 200 to 600, Sorbeth-30, urea, lactic acid and its salts, mucopolysaccharides such as ialuronic acid and chondroitin sulphate, orotic acid, lanolin, petrolatum, mineral oils,' occlusive substances which hydrate the skin by preventing the evaporation of water, and their mixtures.
6. The composition according to any of Claims 1 to 5, wherein the said further self-preservative agent is selected from the group consisting of: formaldehyde, chloride, hypochlorite, compounds releasing chlorine, bioxide of chlorine, iodine and iodophers, phenol, cresol, chlorocresol, amphoteric compounds with self-preservative characteristics, chlorhexidine, peracetic acid and dihydroacetic acid, compounds of mercury, alcohols, sorbic acid, benzoic acid, salicylic acid, boric acid, formic acid, propionic acid and salts derived from these, bronopol, 5-bromo-5-nitrodioxane, hexamethylene tetramine, DMDM idantoine, various idantoines such as MDM idantoine, chloracetamide, ureas such as imidazolidinyl urea and diazodinyl urea, inorganic sulphites, trichlosane, parabenes, isothiazolinones, usnic acid and its salts, chlorophene, hexachlorophene, dichlorophene, bromochlorophene, trichlorocarbon, chlorofluorocarbon, benzamidines classified as self-preservatives, amines classified as self-preservatives, dimethyloxazolidine, ethylbicycloxazolidine, dimethyl hydroxymethyl pirazol, polyaminopropyl biguanide, sodium hydroxymethylglycinate, methyldibromoglutaronitrile, glyceryl monolaurate and their mixtures .
7. The composition according to any of Claims 1 to 6, including a further and separate surfactant agent selected from anionic, cationic, non-ionic, amphoteric surfactants and their mixtures .
8. The composition according to Claim 7, wherein the said further and separate surfactant agent is selected from sodium laurylsulphate, sodium laurylethoxysulphate and their mixtures .
9. The composition according to any of Claims 1 to 8, wherein the concentration of the said salt is in the range from 0.5 to 25% by weight of active material with respect to the total weight of the composition.
10. The composition according to Claim 9, in which the said concentration is in the range of 1.5 to 15% by weight of active material .
11. Use of capryloyl glutamate and/or capryloyl hydrolysate salts of wheat and/or rice pro.teins as self-preservative and hydrating agents and simultaneously as sebum regulating, anti-dandruff and/or anti-odour agents in the formulation of a detergent or cosmetic composition as defined in any of Claims 1 to 10.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001TO001053A ITTO20011053A1 (en) | 2001-11-07 | 2001-11-07 | USE OF GLUTAMATED CAPRILOIL E-OR HYDROLY CAPRILOIL SALTS OF E-OR RICE WHEAT PROTEINS IN THE FORMULATION OF DETERGENT OR DETERGENT COMPOSITIONS |
| ITTO2001A001053 | 2001-11-07 | ||
| PCT/EP2002/012369 WO2003039496A1 (en) | 2001-11-07 | 2002-11-06 | Detergent and cosmetic compositions comprising capryloyl glutamate salts and/or capryloyl hydrolysate salts of wheat and/or rice protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002350672A1 true AU2002350672A1 (en) | 2003-07-24 |
| AU2002350672B2 AU2002350672B2 (en) | 2007-03-01 |
Family
ID=11459287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002350672A Expired AU2002350672B2 (en) | 2001-11-07 | 2002-11-06 | Detergent and cosmetic compositions comprising capryloyl glutamate salts and/or capryloyl hydrolysate salts of wheat and/or rice protein |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050008601A1 (en) |
| EP (1) | EP1446092B1 (en) |
| AU (1) | AU2002350672B2 (en) |
| DE (1) | DE60228305D1 (en) |
| ES (1) | ES2307804T3 (en) |
| IT (1) | ITTO20011053A1 (en) |
| WO (1) | WO2003039496A1 (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITTO20030555A1 (en) * | 2003-07-17 | 2005-01-18 | Zschimmer & Schwarz Italiana S P A | DETERGENT COMPOSITION BASED ON OLEOSE SUBSTANCES. |
| DE102004046063A1 (en) * | 2004-09-22 | 2006-03-23 | Henkel Kgaa | Hair treatment agent, useful to decrease olfactory absorption in keratinic fibers, comprises apolar components and protein-complex trace elements of e.g. zinc, magnesium, potassium or ferrous |
| JP2006273770A (en) * | 2005-03-30 | 2006-10-12 | Nof Corp | Body detergent composition |
| JP5038656B2 (en) * | 2005-11-18 | 2012-10-03 | 花王株式会社 | Deodorant composition |
| CN1966090B (en) | 2005-11-18 | 2012-09-05 | 花王株式会社 | Deodorant compositions |
| JP5038632B2 (en) * | 2006-02-08 | 2012-10-03 | 花王株式会社 | Deodorant composition |
| JP5139639B2 (en) * | 2006-03-03 | 2013-02-06 | 花王株式会社 | Deodorant composition |
| JP5139643B2 (en) * | 2006-04-28 | 2013-02-06 | 花王株式会社 | Liquid deodorant composition |
| JP5438518B2 (en) | 2006-12-13 | 2014-03-12 | センテニアル ヴェンチャーズ ビー．ブイ． | Less irritating composition for skin sterilization |
| ITTO20080277A1 (en) * | 2008-04-10 | 2009-10-11 | Zschimmer & Schwarz Italiana Spa | CONCENTRATED BASE FOR DETERGENT PRODUCTS AND PRODUCTS FOR THE CARE AND HYGIENE OF THE PERSON INCLUDING A COMBINATION OF AT LEAST THREE NON-ETSOXYLATED SURFACES |
| US9044141B2 (en) * | 2010-02-10 | 2015-06-02 | Tokitae Llc | Systems, devices, and methods including a dark-field reflected-illumination apparatus |
| FR2996127B1 (en) * | 2012-09-28 | 2015-07-24 | Fabre Pierre Dermo Cosmetique | USE OF (2S) -2-AMINOPENTANEDIOIC ACID FOR THE TREATMENT OF SEBORRHEA |
| CN104768523B (en) | 2012-10-29 | 2017-08-15 | 宝洁公司 | There is 0.30 or the more personal care composition of lossy angle tangent value at 10 DEG C |
| PL3253207T3 (en) * | 2015-02-05 | 2020-05-18 | Hygienix Bv | Method for disinfecting a surface, and composition suitable for use therein |
| GR1009087B (en) * | 2016-06-01 | 2017-08-11 | ΦΑΡΜΑΣΕΠΤ - ΕΙΣΑΓ - ΑΝΤΙΠΡΟΣΩΠΕΙΕΣ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΕΙΔΩΝ με δ.τ. "PHARMASEPT Ε.Π.Ε. | Components for the production of cosmetic products |
| CN106038348A (en) * | 2016-07-04 | 2016-10-26 | 广州环亚化妆品科技有限公司 | Antiseptic composition and application thereof in cosmetics |
| WO2018143911A1 (en) | 2017-01-31 | 2018-08-09 | Kimberly-Clark Worldwide, Inc. | Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same |
| CN110785161B (en) | 2017-06-23 | 2023-06-20 | 宝洁公司 | Compositions and methods for improving the appearance of skin |
| WO2019088249A1 (en) * | 2017-11-06 | 2019-05-09 | 味の素株式会社 | Detergent composition |
| CA3102288A1 (en) | 2018-07-03 | 2020-01-09 | The Procter & Gamble Company | Method of treating a skin condition |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| WO2021247496A1 (en) | 2020-06-01 | 2021-12-09 | The Procter & Gamble Company | Method of improving penetration of a vitamin b3 compound into skin |
| FR3114744B1 (en) | 2020-10-02 | 2024-01-05 | Basf Beauty Care Solutions France Sas | New use of a peptide to improve the comfort of the skin and/or mucous membranes and/or the appearance of skin appendages |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03294298A (en) * | 1990-04-13 | 1991-12-25 | Seiwa Kasei:Kk | Acylated substance of vegetable protein polypeptide or salt thereof |
| JP2902792B2 (en) * | 1991-01-22 | 1999-06-07 | 鐘紡株式会社 | Hypoallergenic detergent composition |
| FR2676922B1 (en) * | 1991-06-03 | 1995-01-20 | Givaudan Lavirotte | COSMETIC APPLICATIONS OF N-ACYL DERIVATIVES OF MIXTURES OF AMINO ACIDS DERIVED FROM VEGETABLE PROTEIN HYDROLYSATES. |
| FR2760746B3 (en) * | 1997-03-14 | 1999-05-21 | Phytocos Lab | NEW ACYLAMINOACIDS |
| FR2765109B1 (en) * | 1997-06-25 | 2001-02-09 | Seppic Sa | COMPOSITION COMPRISING A LIPOAMINOACID AND THE CONSTITUENTS OF A TANNIN-RICH PLANT EXTRACT AND USE IN COSMETICS |
| IT1307262B1 (en) * | 1999-07-20 | 2001-10-30 | Zschimmer & Schwarz Italiana S | DETERGENT OR COSMETIC COMPOSITIONS INCLUDING ALCHYL SULPHATES AND / OALKYL (POLES) ZINC ETHOXY SULPHATES SUCH AS SURFACTIVE AGENTS AND |
| DE10102009A1 (en) * | 2001-01-18 | 2002-08-01 | Cognis Deutschland Gmbh | surfactant mixture |
| DE10102007A1 (en) * | 2001-01-18 | 2002-10-10 | Cognis Deutschland Gmbh | surfactant mixture |
| RU2003138141A (en) * | 2001-06-01 | 2005-06-10 | Хенкель Кгаа (De) | Arylsulfatase Inhibitors in Deodorants and Antiperspirants |
-
2001
- 2001-11-07 IT IT2001TO001053A patent/ITTO20011053A1/en unknown
-
2002
- 2002-11-06 WO PCT/EP2002/012369 patent/WO2003039496A1/en active IP Right Grant
- 2002-11-06 AU AU2002350672A patent/AU2002350672B2/en not_active Expired
- 2002-11-06 EP EP02785364A patent/EP1446092B1/en not_active Expired - Lifetime
- 2002-11-06 US US10/494,733 patent/US20050008601A1/en not_active Abandoned
- 2002-11-06 DE DE60228305T patent/DE60228305D1/en not_active Expired - Lifetime
- 2002-11-06 ES ES02785364T patent/ES2307804T3/en not_active Expired - Lifetime
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