AU2002342752B2 - Polycyclic compounds having anti-tumor activity - Google Patents

Polycyclic compounds having anti-tumor activity Download PDF

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Publication number
AU2002342752B2
AU2002342752B2 AU2002342752A AU2002342752A AU2002342752B2 AU 2002342752 B2 AU2002342752 B2 AU 2002342752B2 AU 2002342752 A AU2002342752 A AU 2002342752A AU 2002342752 A AU2002342752 A AU 2002342752A AU 2002342752 B2 AU2002342752 B2 AU 2002342752B2
Authority
AU
Australia
Prior art keywords
benzo
diaza
fluoren
ethylamino
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002342752A
Other languages
English (en)
Other versions
AU2002342752A1 (en
Inventor
Tsunehisa Aoyama
Kenichi Kawasaki
Miyako Masubuchi
Tatsuo Ohtsuka
Kiyoaki Sakata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2002342752A1 publication Critical patent/AU2002342752A1/en
Application granted granted Critical
Publication of AU2002342752B2 publication Critical patent/AU2002342752B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2002342752A 2001-10-05 2002-09-25 Polycyclic compounds having anti-tumor activity Ceased AU2002342752B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01123908 2001-10-05
EP01123908.4 2001-10-05
PCT/EP2002/010722 WO2003031444A1 (fr) 2001-10-05 2002-09-25 Composes polycycliques a activite antitumorale

Publications (2)

Publication Number Publication Date
AU2002342752A1 AU2002342752A1 (en) 2003-07-03
AU2002342752B2 true AU2002342752B2 (en) 2007-11-15

Family

ID=8178868

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002342752A Ceased AU2002342752B2 (en) 2001-10-05 2002-09-25 Polycyclic compounds having anti-tumor activity

Country Status (16)

Country Link
US (1) US6680326B2 (fr)
EP (1) EP1436293B1 (fr)
JP (1) JP4369229B2 (fr)
KR (1) KR100676114B1 (fr)
CN (1) CN1284781C (fr)
AR (1) AR037327A1 (fr)
AT (1) ATE316971T1 (fr)
AU (1) AU2002342752B2 (fr)
BR (1) BR0213122A (fr)
CA (1) CA2461572C (fr)
DE (1) DE60209029T2 (fr)
ES (1) ES2256552T3 (fr)
MX (1) MXPA04003173A (fr)
PL (1) PL370530A1 (fr)
RU (1) RU2315050C2 (fr)
WO (1) WO2003031444A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946472B2 (en) * 2002-04-30 2005-09-20 Hoffman-La Roche Inc. Polycyclic compounds exhibiting anti-tumor activities
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
CN103204781B (zh) * 2013-03-14 2015-04-01 武汉大学 2,7–二取代芴酮衍生物及其制备方法与应用
CN110448555B (zh) * 2019-09-10 2020-10-23 河南省人民医院 多环化合物在制备抗肿瘤药物中的应用及抗肿瘤药物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0713870A1 (fr) * 1994-05-20 1996-05-29 Taiho Pharmaceutical Co., Ltd. Nouveau derive d'indane fusionne et sel dudit derive acceptable pharmaceutiquement

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045272A1 (fr) * 1997-04-07 1998-10-15 Latrobe University Inhibiteurs de la topoisomerase
FR2801309B1 (fr) 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0713870A1 (fr) * 1994-05-20 1996-05-29 Taiho Pharmaceutical Co., Ltd. Nouveau derive d'indane fusionne et sel dudit derive acceptable pharmaceutiquement

Also Published As

Publication number Publication date
KR100676114B1 (ko) 2007-02-02
AR037327A1 (es) 2004-11-03
CN1610681A (zh) 2005-04-27
PL370530A1 (en) 2005-05-30
CN1284781C (zh) 2006-11-15
EP1436293B1 (fr) 2006-02-01
ES2256552T3 (es) 2006-07-16
EP1436293A1 (fr) 2004-07-14
DE60209029T2 (de) 2006-09-28
MXPA04003173A (es) 2004-07-27
JP2005504846A (ja) 2005-02-17
US6680326B2 (en) 2004-01-20
JP4369229B2 (ja) 2009-11-18
CA2461572A1 (fr) 2003-04-17
KR20040048926A (ko) 2004-06-10
BR0213122A (pt) 2004-09-21
DE60209029D1 (de) 2006-04-13
RU2004114245A (ru) 2005-06-27
RU2315050C2 (ru) 2008-01-20
ATE316971T1 (de) 2006-02-15
US20030073691A1 (en) 2003-04-17
CA2461572C (fr) 2011-02-15
WO2003031444A1 (fr) 2003-04-17

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired