AU2002317402B2 - Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety - Google Patents

Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety Download PDF

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Publication number
AU2002317402B2
AU2002317402B2 AU2002317402A AU2002317402A AU2002317402B2 AU 2002317402 B2 AU2002317402 B2 AU 2002317402B2 AU 2002317402 A AU2002317402 A AU 2002317402A AU 2002317402 A AU2002317402 A AU 2002317402A AU 2002317402 B2 AU2002317402 B2 AU 2002317402B2
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Australia
Prior art keywords
group
yne
polar
compound
hydrocarbyl group
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AU2002317402A
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AU2002317402A1 (en
Inventor
Steven Fletcher
Michael R. Jorgensen
Andrew David Miller
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Imuthes Ltd
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Imuthes Ltd
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Assigned to IMUTHES LIMITED reassignment IMUTHES LIMITED Request for Assignment Assignors: MITSUBISHI CHEMICAL CORPORATION
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
AU2002317402A 2001-07-30 2002-07-29 Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety Ceased AU2002317402B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0118517.2A GB0118517D0 (en) 2001-07-30 2001-07-30 Compound
GB0118517.2 2001-07-30
PCT/GB2002/003488 WO2003011252A1 (en) 2001-07-30 2002-07-29 Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety

Publications (2)

Publication Number Publication Date
AU2002317402A1 AU2002317402A1 (en) 2003-05-29
AU2002317402B2 true AU2002317402B2 (en) 2008-08-28

Family

ID=9919439

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002317402A Ceased AU2002317402B2 (en) 2001-07-30 2002-07-29 Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety

Country Status (9)

Country Link
US (1) US20040219202A1 (enExample)
EP (1) EP1411898A1 (enExample)
JP (1) JP2005505521A (enExample)
CN (1) CN100457088C (enExample)
AU (1) AU2002317402B2 (enExample)
CA (1) CA2451868A1 (enExample)
GB (1) GB0118517D0 (enExample)
RU (1) RU2294738C2 (enExample)
WO (1) WO2003011252A1 (enExample)

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DE10236146A1 (de) * 2002-07-31 2004-02-19 Basf Coatings Ag Beschichtungsstoff, Verfahren zu seiner Herstellung und seine Verwendung
EP1888033B1 (en) * 2005-06-09 2014-02-19 Meda AB Method and composition for treating inflammatory disorders
CA3144493A1 (en) * 2006-10-03 2008-04-10 Arbutus Biopharma Corporation Lipid containing formulations
US20110002851A1 (en) * 2006-11-03 2011-01-06 Medigene Ag Cationic Colloidal Carriers for Delivery of Active Agents to the Blood-Brain Barrier in the Course of Neuroinflammatory Diseases
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
EP2105145A1 (en) 2008-03-27 2009-09-30 ETH Zürich Method for muscle-specific delivery lipid-conjugated oligonucleotides
AU2009236306B2 (en) * 2008-04-17 2015-04-02 Pds Biotechnology Corporation Stimulation of an immune response by enantiomers of cationic lipids
EP3699172A3 (en) 2008-11-10 2020-11-18 Arbutus Biopharma Corporation Novel lipids and compositions for the delivery of therapeutics
RU2394834C1 (ru) * 2009-06-29 2010-07-20 Учреждение Российской академии наук Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) Углеводсодержащие катионные амфифилы, обладающие способностью доставлять нуклеиновые кислоты в клетки млекопитающих
US9352042B2 (en) * 2012-02-24 2016-05-31 Protiva Biotherapeutics, Inc. Trialkyl cationic lipids and methods of use thereof
US10286064B2 (en) 2012-06-15 2019-05-14 Pds Biotechnology Corporation Cationic lipid vaccine compositions and methods of use
BR112015000174A2 (pt) 2012-07-05 2017-06-27 Taiwan Liposome Co Ltd método para o tratamento da artrite
AU2013317805B2 (en) 2012-09-21 2018-07-26 Pds Biotechnology Corporation Improved vaccine compositions and methods of use
US9801799B2 (en) 2013-08-30 2017-10-31 Dalhousia University Compositions and methods for the removal of tattoos
US11612652B2 (en) 2015-11-13 2023-03-28 Pds Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
EP3377043A4 (en) * 2015-11-20 2019-06-26 The Regents of The University of California DEVICABLE NANOSCAL CARRIER (DNVS) FOR ADMINISTRATION THROUGH THE BLOOD-BRAIN-BARRIER, MICE AND SKIN
CN110662532A (zh) 2017-04-03 2020-01-07 加利福尼亚大学董事会 用于跨血脑屏障、透粘膜和经皮药物递送的可变形的纳米级媒介物(dnvs)
TW201924722A (zh) 2017-12-05 2019-07-01 美商Ｐｄｓ生技公司 用於刺激第i型干擾素基因之方法及包含陽離子脂質的組合物

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Rurup et al. Chemistry and Physics of Lipids (1994) vol. 70, no. 2 pages 187-198 *
Stanish et al. Chemistry and Physics of Lipids (2001) vol. 112 pages 99-108 *

Also Published As

Publication number Publication date
JP2005505521A (ja) 2005-02-24
CA2451868A1 (en) 2003-02-13
WO2003011252A1 (en) 2003-02-13
CN1561199A (zh) 2005-01-05
EP1411898A1 (en) 2004-04-28
CN100457088C (zh) 2009-02-04
GB0118517D0 (en) 2001-09-19
US20040219202A1 (en) 2004-11-04
RU2004106154A (ru) 2005-05-10
RU2294738C2 (ru) 2007-03-10

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