AU2002308676B2 - Carbon monoxide as a biomarker and therapeutic agent - Google Patents

Carbon monoxide as a biomarker and therapeutic agent Download PDF

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Publication number
AU2002308676B2
AU2002308676B2 AU2002308676A AU2002308676A AU2002308676B2 AU 2002308676 B2 AU2002308676 B2 AU 2002308676B2 AU 2002308676 A AU2002308676 A AU 2002308676A AU 2002308676 A AU2002308676 A AU 2002308676A AU 2002308676 B2 AU2002308676 B2 AU 2002308676B2
Authority
AU
Australia
Prior art keywords
carbon monoxide
patient
disease
composition
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002308676A
Other languages
English (en)
Other versions
AU2002308676A1 (en
Inventor
Augustine M. K. Choi
Leo E. Otterbein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Johns Hopkins University
Original Assignee
Yale University
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University, Johns Hopkins University filed Critical Yale University
Publication of AU2002308676A1 publication Critical patent/AU2002308676A1/en
Application granted granted Critical
Publication of AU2002308676B2 publication Critical patent/AU2002308676B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/44—Elemental carbon, e.g. charcoal, carbon black
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2002308676A 2002-05-09 2002-05-09 Carbon monoxide as a biomarker and therapeutic agent Ceased AU2002308676B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/014836 WO2003094932A1 (fr) 2002-05-09 2002-05-09 Monoxyde de carbone servant de biomarqueur et d'agent therapeutique

Publications (2)

Publication Number Publication Date
AU2002308676A1 AU2002308676A1 (en) 2003-11-11
AU2002308676B2 true AU2002308676B2 (en) 2009-06-11

Family

ID=29418043

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002308676A Ceased AU2002308676B2 (en) 2002-05-09 2002-05-09 Carbon monoxide as a biomarker and therapeutic agent

Country Status (13)

Country Link
EP (1) EP1501523A4 (fr)
JP (1) JP2005532314A (fr)
KR (1) KR20040106515A (fr)
CN (1) CN1638781A (fr)
AU (1) AU2002308676B2 (fr)
BR (1) BR0215717A (fr)
CA (1) CA2484770A1 (fr)
EA (1) EA200401478A1 (fr)
MX (1) MXPA04011113A (fr)
NO (1) NO20044865L (fr)
RS (1) RS96904A (fr)
UA (1) UA84402C2 (fr)
WO (1) WO2003094932A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7678390B2 (en) 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
GB0111872D0 (en) 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
US7011854B2 (en) 2002-02-04 2006-03-14 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
AU2003216368B2 (en) 2002-04-15 2007-08-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating ileus
RS91104A (en) 2002-04-15 2007-02-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Methods of treating necrotizing enterocolitis
CN1668314B (zh) * 2002-05-17 2011-01-12 耶鲁大学 治疗肝炎的方法
JP2005345242A (ja) * 2004-06-02 2005-12-15 Tohoku Univ 肺癌の化学療法治療効果の評価方法
JPWO2007073005A1 (ja) * 2005-12-22 2009-06-04 学校法人慶應義塾 メチル基転移反応調節物質
WO2008069688A2 (fr) * 2006-12-06 2008-06-12 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Procédés de traitement d'une maladie inflammatoire par administration d'aldéhydes et de dérivés de ceux-ci
JP2010094122A (ja) 2008-06-12 2010-04-30 Keio Gijuku バイオマーカーとしてのマイクロｒｎａを用いた頭頸部腫瘍の診断・治療選択
JP2012046470A (ja) * 2010-08-30 2012-03-08 Japan Science & Technology Agency Ｇａｐｄｈの酵素活性阻害剤
EP2663193B1 (fr) * 2011-01-14 2019-05-08 Children's Hospital Los Angeles Solution de monoxyde de carbone utilisable en vue du traitement d'une maladie, notamment la drépanocytose
US8927750B2 (en) 2011-02-04 2015-01-06 Universitaet Zu Koeln Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules
US9359197B2 (en) 2011-03-24 2016-06-07 Technion Research & Development Foundation Ltd. Method of diagnosing, prognosing and monitoring parkinson's disease
ES2656237T3 (es) 2011-04-19 2018-02-26 Alfama, Inc. Moléculas liberadoras de monóxido de carbono y usos de las mismas
EP2734235B1 (fr) 2011-07-21 2017-03-22 Alfama, Inc. Molécules libérant du ruthénium-monoxyde de carbone et utilisations de celles-ci
US10031126B2 (en) 2013-04-04 2018-07-24 The Regents Of The University Of California System and method for utilizing exhaled breath for monitoring inflammatory states
EP2868348A1 (fr) * 2013-11-04 2015-05-06 Universität Zürich Composés à libération de monoxide de carbone et leurs formulations utiles pour induire la biogenèse mitochondriale et la réparation tissulaire
TW201618795A (zh) * 2014-04-15 2016-06-01 波泰里斯股份有限公司 用以改良器官功能及延長器官移植物壽命之系統及方法
JP7161737B2 (ja) * 2017-01-30 2022-10-27 哲也 石川 悪性腫瘍の検査方法
WO2019235166A1 (fr) * 2018-06-08 2019-12-12 住友精化株式会社 Composition pour le traitement de plaies cutanées
US11576929B2 (en) 2018-06-08 2023-02-14 Sumitomo Seika Chemicals Co., Ltd. Composition for inflammatory gastrointestinal disorders
WO2020247825A1 (fr) * 2019-06-06 2020-12-10 The General Hospital Corporation Monoxyde de carbone en tant que traitement pour une maladie neurodégénérative
US20230346831A1 (en) * 2020-07-16 2023-11-02 Cornell University Methods for treating metastatic cancer using low dose carbon monoxide
US11881093B2 (en) 2020-08-20 2024-01-23 Denso International America, Inc. Systems and methods for identifying smoking in vehicles
US11828210B2 (en) 2020-08-20 2023-11-28 Denso International America, Inc. Diagnostic systems and methods of vehicles using olfaction
US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
US11760169B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Particulate control systems and methods for olfaction sensors
US12017506B2 (en) 2020-08-20 2024-06-25 Denso International America, Inc. Passenger cabin air control systems and methods
US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
US11813926B2 (en) 2020-08-20 2023-11-14 Denso International America, Inc. Binding agent and olfaction sensor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5293875A (en) * 1992-06-16 1994-03-15 Natus Medical Incorporated In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421433C1 (de) * 1994-06-18 1995-06-08 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung
ES2210585T3 (es) * 1996-08-27 2004-07-01 Messer Griesheim Gmbh Medicamento que contiene hidrogeno.
US20030068387A1 (en) * 2001-03-30 2003-04-10 Roland Buelow Carbon monoxide generating compounds for treatment of vascular, inflammatory and immune disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5293875A (en) * 1992-06-16 1994-03-15 Natus Medical Incorporated In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Abidin et al., Kosmicheskaya Biologiya I Aviakosmicheskaya Meditsina.1978, Vol.6, pages 63-67 (X) *
Choi et al., Am. J. Respir. Cell Mol. Biol. 1996, Vol. 15, No. 1, pages 9-19. (Y) *
Lefer et al., Meth. Find. Exp. Clin. Pharmacol. 1993, Vol. l5, No. 9, pages 617-22. (Y) *
Otterbein et al., The American Physiological Society. 1999, Vol. 276, pages L688-L694. (X) *
Vassalli et al., European Respiratory Journal. 1998, Vol 12, Suppl. 28, 237s. (Y) *
Yuan et al., Chinese Medical Sciences Journal.1997, Vol. 12, No. 4, pages 212-15. (Y) *

Also Published As

Publication number Publication date
NO20044865L (no) 2004-12-07
BR0215717A (pt) 2005-02-22
EP1501523A1 (fr) 2005-02-02
CN1638781A (zh) 2005-07-13
KR20040106515A (ko) 2004-12-17
JP2005532314A (ja) 2005-10-27
CA2484770A1 (fr) 2003-11-20
MXPA04011113A (es) 2005-02-14
EA200401478A1 (ru) 2005-12-29
RS96904A (en) 2007-02-05
AU2002308676A1 (en) 2003-11-11
EP1501523A4 (fr) 2006-12-13
WO2003094932A1 (fr) 2003-11-20
UA84402C2 (ru) 2008-10-27

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 18, NO 2, PAGE(S) 584 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME SHINAGAWA REFRACTORIES CO., APPLICATION NO. 2002308676, UNDER INID (43) CORRECT PUBLICATION DATE TO READ 24 NOVEMBER 2003.

Free format text: IN VOL 18, NO 2, PAGE(S) 612 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME JOHNS HOPKINS UNIVERSITY, APPLICATION NO. 2002308676, UNDER INID (43) CORRECT PUBLICATION DATE TO READ 24 NOVEMBER 2003.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired