AU2001294542B8 - Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis - Google Patents

Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis Download PDF

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Publication number
AU2001294542B8
AU2001294542B8 AU2001294542A AU2001294542A AU2001294542B8 AU 2001294542 B8 AU2001294542 B8 AU 2001294542B8 AU 2001294542 A AU2001294542 A AU 2001294542A AU 2001294542 A AU2001294542 A AU 2001294542A AU 2001294542 B8 AU2001294542 B8 AU 2001294542B8
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probe
seq
probes
nos
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AU2001294542A1 (en
AU2001294542B2 (en
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John Connaughton
Joseph G. Utermohlen
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Ventana Medical Systems Inc
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Ventana Medical Systems Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001294542A 2000-09-15 2001-09-06 Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis Expired AU2001294542B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23317700P 2000-09-15 2000-09-15
US60/233,177 2000-09-15
PCT/US2001/028014 WO2002022874A2 (en) 2000-09-15 2001-09-06 Oligonucleotides for labeling oligonucleotide probes and proteins

Publications (3)

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AU2001294542A1 AU2001294542A1 (en) 2002-06-13
AU2001294542B2 AU2001294542B2 (en) 2008-04-03
AU2001294542B8 true AU2001294542B8 (en) 2008-07-03

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AU2001294542A Expired AU2001294542B8 (en) 2000-09-15 2001-09-06 Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis
AU9454201A Pending AU9454201A (en) 2000-09-15 2001-09-06 Oligonucleotide sequence formula for labeling oligonucleotide probe and proteinsfor in-situ analysis

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US (3) US7838655B2 (enExample)
EP (1) EP1366187B1 (enExample)
JP (2) JP4986367B2 (enExample)
AT (1) ATE415491T1 (enExample)
AU (2) AU2001294542B8 (enExample)
CA (2) CA2703141C (enExample)
DE (1) DE60136746D1 (enExample)
DK (1) DK1366187T3 (enExample)
ES (1) ES2317939T3 (enExample)
WO (1) WO2002022874A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7838655B2 (en) * 2000-09-15 2010-11-23 Ventana Medical Systems, Inc. Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis
WO2002099135A1 (en) * 2001-06-06 2002-12-12 Canag Diagnostics Ab Method to measure gene expression ratio of key genes
US8574836B2 (en) * 2005-01-12 2013-11-05 Ramesh Vallabhaneni Method and apparatus for chromosome profiling
EP3219812B1 (en) 2008-05-27 2020-09-02 Agilent Technologies, Inc. Hybridization compositions and methods
WO2010030818A2 (en) 2008-09-10 2010-03-18 University Of Medicine And Dentistry Of New Jersey IMAGING INDIVIDUAL mRNA MOLECULES USING MULTIPLE SINGLY LABELED PROBES
US9303287B2 (en) 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
JP2012529908A (ja) 2009-06-15 2012-11-29 ネットバイオ・インコーポレーテッド 法医学的ｄｎａの定量化のための改善された方法
WO2019219651A1 (en) 2018-05-15 2019-11-21 Ventana Medical Systems, Inc. Quantitation of signal in stain aggregates
MX2022012272A (es) * 2020-03-31 2023-02-23 Personal Genome Diagnostics Inc Composiciones y metodos para determinar la calidad del acido nucleico.
CN115948608A (zh) * 2022-08-05 2023-04-11 北京中杉金桥生物技术有限公司 一种用于eber检测的探针组及试剂盒

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948922A (en) * 1973-01-02 1976-04-06 Lowe Orville G Oxidation of thiols and disulfides to sulfonic acids
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
US5489507A (en) * 1988-11-30 1996-02-06 Perkin-Elmer Corporation DNA detection by color complementation
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
US5789161A (en) * 1990-09-20 1998-08-04 Amoco Corporation Methods for genome identification using direct label probe composition
US5843660A (en) * 1994-09-30 1998-12-01 Promega Corporation Multiplex amplification of short tandem repeat loci
US5684142A (en) * 1995-06-07 1997-11-04 Oncor, Inc. Modified nucleotides for nucleic acid labeling
US5871917A (en) * 1996-05-31 1999-02-16 North Shore University Hospital Research Corp. Identification of differentially methylated and mutated nucleic acids
US7504493B2 (en) * 1997-01-23 2009-03-17 The John Hopkins University Characterization of the yeast transcriptome
US7838655B2 (en) * 2000-09-15 2010-11-23 Ventana Medical Systems, Inc. Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis
US7399339B2 (en) * 2005-06-15 2008-07-15 Gas Technology Institute Polyoxometalate material for gaseous stream purification at high temperature

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHU et al Protein Science (1994): 3:2115-2128 *

Also Published As

Publication number Publication date
US8524877B2 (en) 2013-09-03
JP2012065660A (ja) 2012-04-05
WO2002022874A9 (en) 2003-04-03
JP5272063B2 (ja) 2013-08-28
CA2703141A1 (en) 2002-03-21
EP1366187B1 (en) 2008-11-26
DE60136746D1 (de) 2009-01-08
ATE415491T1 (de) 2008-12-15
US7838655B2 (en) 2010-11-23
AU2001294542B2 (en) 2008-04-03
CA2422440C (en) 2010-07-27
CA2703141C (en) 2014-10-21
US20110034682A1 (en) 2011-02-10
AU9454201A (en) 2002-03-26
JP2005503753A (ja) 2005-02-10
ES2317939T3 (es) 2009-05-01
JP4986367B2 (ja) 2012-07-25
US20040014088A1 (en) 2004-01-22
WO2002022874A3 (en) 2003-09-25
DK1366187T3 (da) 2009-02-16
US20120309951A1 (en) 2012-12-06
CA2422440A1 (en) 2002-03-21
WO2002022874A2 (en) 2002-03-21
EP1366187A2 (en) 2003-12-03
WO2002022874A8 (en) 2003-07-10
US8236502B2 (en) 2012-08-07

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MK3 Application lapsed section 142(2)(c) - examination deferred under section 46 no request for examination
NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO REQUEST EXAMINATION HAS BEEN EXTENDED TO 20 JUL 2005.

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Free format text: IN VOL 22, NO 13, PAGE(S) 1586 UNDER THE HEADING APPLICATIONS ACCEPTED -NAME INDEX UNDER THE NAME VENTANA MEDICAL SYSTEMS, INC, APPLICATION NO. 2001294542, UNDER INID(54), CORRECT THE INVENTION TITLE TO READ OLIGONUCLEOTIDE SEQUENCE FORMULA FOR LABELING OLIGONUCLEOTIDE PROBES AND PROTEINS FOR IN-SITU ANALYSIS

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired