AU2001292503A1 - New oxabispidine compound useful in the treatment of cardiac arrhythmias - Google Patents

New oxabispidine compound useful in the treatment of cardiac arrhythmias

Info

Publication number
AU2001292503A1
AU2001292503A1 AU2001292503A AU9250301A AU2001292503A1 AU 2001292503 A1 AU2001292503 A1 AU 2001292503A1 AU 2001292503 A AU2001292503 A AU 2001292503A AU 9250301 A AU9250301 A AU 9250301A AU 2001292503 A1 AU2001292503 A1 AU 2001292503A1
Authority
AU
Australia
Prior art keywords
compound
added
solution
diazabicyclo
oxa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001292503A
Other languages
English (en)
Inventor
Magnus Bjorsne
David Cladingboel
Fritiof Ponten
Gert Strandlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/SE2000/001994 external-priority patent/WO2001028992A2/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2001292503A1 publication Critical patent/AU2001292503A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU2001292503A 2000-10-02 2001-10-01 New oxabispidine compound useful in the treatment of cardiac arrhythmias Abandoned AU2001292503A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PH12000002701 2000-10-02
PH1-2000-02701 2000-10-02
AUPCT/SE2000/001994 2000-10-13
PCT/SE2000/001994 WO2001028992A2 (en) 1999-10-18 2000-10-13 New oxabispidine compounds useful in the treatment of cardiac arrhythmias
PCT/SE2001/002129 WO2002028863A1 (en) 2000-10-02 2001-10-01 New oxabispidine compound useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
AU2001292503A1 true AU2001292503A1 (en) 2002-04-15

Family

ID=52573779

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2001292504A Ceased AU2001292504B2 (en) 2000-10-02 2001-10-01 New process for the production of oxabispidines
AU9250401A Pending AU9250401A (en) 2000-10-02 2001-10-01 New process for the production of oxabispidines
AU2001292503A Abandoned AU2001292503A1 (en) 2000-10-02 2001-10-01 New oxabispidine compound useful in the treatment of cardiac arrhythmias

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AU2001292504A Ceased AU2001292504B2 (en) 2000-10-02 2001-10-01 New process for the production of oxabispidines
AU9250401A Pending AU9250401A (en) 2000-10-02 2001-10-01 New process for the production of oxabispidines

Country Status (22)

Country Link
US (5) US20040039199A1 (de)
EP (3) EP1330461A1 (de)
JP (2) JP2004510775A (de)
KR (2) KR100812920B1 (de)
CN (3) CN1243754C (de)
AR (1) AR030756A1 (de)
AU (3) AU2001292504B2 (de)
BR (2) BR0114367A (de)
CA (2) CA2422810A1 (de)
CZ (1) CZ294217B6 (de)
EE (1) EE200300131A (de)
HU (1) HUP0302288A3 (de)
IL (3) IL154802A0 (de)
IS (1) IS6744A (de)
MX (2) MXPA03002679A (de)
NO (2) NO20031413L (de)
NZ (2) NZ524573A (de)
PL (1) PL364047A1 (de)
RU (1) RU2003107668A (de)
SK (1) SK3862003A3 (de)
WO (2) WO2002028864A1 (de)
ZA (2) ZA200301757B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115054728A (zh) * 2022-07-18 2022-09-16 中国科学院大学宁波华美医院 一种仿生骨组织工程支架材料及其制备方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate
SE0401540D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
AU2006258293B2 (en) 2005-06-13 2010-06-17 Astrazeneca Ab New oxabispidine compounds for the treatment of cardiac arrhythmias
WO2006137771A1 (en) * 2005-06-20 2006-12-28 Astrazeneca Ab Process for the preparation of sulfonic acid salts of oxabispidines
EP1896486A4 (de) * 2005-06-20 2010-11-03 Astrazeneca Ab Verfahren zur herstellung von 3,7-dihydroxy-1,5-diazacyclooctanen
KR20080028435A (ko) * 2005-06-20 2008-03-31 아스트라제네카 아베 Ｎ,ｎ’-이치환된 옥사비스피딘의 제조 방법
AR053901A1 (es) * 2005-06-20 2007-05-23 Astrazeneca Ab Formas fisicas de oxabispidinas n,n'- disustituidas
CN103319423B (zh) * 2013-06-28 2015-10-28 江苏师范大学 一种3,7-双芳基-1,5-二氧-3,7-二氮杂环辛烷的合成方法
KR20150082070A (ko) 2014-01-06 2015-07-15 (주)신비넷 위치 인식 시스템 및 그 시스템에서의 위치 인식을 위한 장치 및 방법
EP3059229A1 (de) 2015-02-17 2016-08-24 Evonik Degussa GmbH Verfahren zur Epoxidierung eines Olefins mit Wasserstoffperoxid

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503939A (en) * 1967-03-29 1970-03-31 Du Pont Polyamides from heterocyclic diamines
DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) * 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
DE3902357A1 (de) 1989-01-27 1990-08-02 Hoechst Ag Verwendung von rheniumorganischen verbindungen zur oxidation von c-c-mehrfachbindungen, darauf basierende oxidationsverfahren und neue rheniumorganische verbindungen
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
US5831099A (en) * 1995-03-10 1998-11-03 The United States Of America As Represented By The Secretary Of The Army Compounds of 1,5-disubstituted-3,7 diaza bicyclo 3.3.0! octanes and products containing the same
US5939568A (en) 1997-01-31 1999-08-17 The Scripps Research Institute Accelerated catalysis of olefinic epoxidations
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SK13422001A3 (sk) * 1999-04-09 2002-05-09 Astrazeneca Ab Adamantánové deriváty
AUPQ274199A0 (en) 1999-09-09 1999-09-30 Ericsson Australia Pty Ltd Information transmission rate control across a core network
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115054728A (zh) * 2022-07-18 2022-09-16 中国科学院大学宁波华美医院 一种仿生骨组织工程支架材料及其制备方法
CN115054728B (zh) * 2022-07-18 2023-11-07 中国科学院大学宁波华美医院 一种仿生骨组织工程支架材料及其制备方法

Also Published As

Publication number Publication date
CZ2003923A3 (cs) 2003-08-13
KR100812920B1 (ko) 2008-03-11
IL154802A0 (en) 2003-10-31
CN1793146A (zh) 2006-06-28
NO20031413D0 (no) 2003-03-27
EP1330462A1 (de) 2003-07-30
NZ524574A (en) 2004-11-26
CN1243754C (zh) 2006-03-01
EE200300131A (et) 2003-06-16
NZ524573A (en) 2004-11-26
US7439355B2 (en) 2008-10-21
US20090240051A1 (en) 2009-09-24
BR0114366A (pt) 2003-08-12
MXPA03002759A (es) 2003-07-28
BR0114367A (pt) 2003-12-09
EP1330461A1 (de) 2003-07-30
MXPA03002679A (es) 2003-06-24
JP2004510775A (ja) 2004-04-08
CA2421776A1 (en) 2002-04-11
RU2003107668A (ru) 2004-11-27
IL154803A (en) 2008-03-20
PL364047A1 (en) 2004-12-13
NO20031414D0 (no) 2003-03-27
AU2001292504B2 (en) 2006-09-07
EP1900741A1 (de) 2008-03-19
ZA200301757B (en) 2004-02-05
IS6744A (is) 2003-03-13
US6936712B1 (en) 2005-08-30
CZ294217B6 (cs) 2004-10-13
JP2004510776A (ja) 2004-04-08
JP4248873B2 (ja) 2009-04-02
WO2002028863A1 (en) 2002-04-11
CA2422810A1 (en) 2002-04-11
CN1468244A (zh) 2004-01-14
WO2002028863A8 (en) 2003-06-05
KR20030032060A (ko) 2003-04-23
IL154803A0 (en) 2003-10-31
SK3862003A3 (en) 2003-10-07
US20090036675A1 (en) 2009-02-05
AU9250401A (en) 2002-04-15
CN1468245A (zh) 2004-01-14
KR20030032061A (ko) 2003-04-23
US20050171100A1 (en) 2005-08-04
AR030756A1 (es) 2003-09-03
NO20031413L (no) 2003-05-22
WO2002028864A1 (en) 2002-04-11
HUP0302288A3 (en) 2004-11-29
HUP0302288A2 (hu) 2003-10-28
US20040039199A1 (en) 2004-02-26
NO20031414L (no) 2003-05-26
ZA200302202B (en) 2004-06-28
EP1900741A8 (de) 2010-08-04

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application