AU2001282373A1 - Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntion - Google Patents
Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntionInfo
- Publication number
- AU2001282373A1 AU2001282373A1 AU2001282373A AU8237301A AU2001282373A1 AU 2001282373 A1 AU2001282373 A1 AU 2001282373A1 AU 2001282373 A AU2001282373 A AU 2001282373A AU 8237301 A AU8237301 A AU 8237301A AU 2001282373 A1 AU2001282373 A1 AU 2001282373A1
- Authority
- AU
- Australia
- Prior art keywords
- proanthocyanidins
- stimulator
- arginine
- salts
- source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 229920002770 condensed tannin Polymers 0.000 title 1
- 230000001856 erectile effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 208000024891 symptom Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20752000P | 2000-05-26 | 2000-05-26 | |
| US60/207,520 | 2000-05-26 | ||
| PCT/IB2001/000910 WO2001089543A2 (en) | 2000-05-26 | 2001-05-24 | Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001282373A1 true AU2001282373A1 (en) | 2001-12-03 |
Family
ID=22770931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001282373A Abandoned AU2001282373A1 (en) | 2000-05-26 | 2001-05-24 | Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntion |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6565851B2 (enExample) |
| JP (1) | JP2003534286A (enExample) |
| AU (1) | AU2001282373A1 (enExample) |
| WO (1) | WO2001089543A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050171030A1 (en) * | 2000-05-26 | 2005-08-04 | Peter Rohdewald | Relieving symptoms of erectile dysfunction and attaining sexual wellness and health of the sexual vascular system with proanthocyanidins |
| AU2001282373A1 (en) * | 2000-05-26 | 2001-12-03 | Horphag Research Limited | Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntion |
| US20040137081A1 (en) * | 2003-01-13 | 2004-07-15 | Peter Rohdewald | Attaining sexual wellness and health of the sexual vascular system with proanthocyanidins |
| JP2003334022A (ja) * | 2002-05-17 | 2003-11-25 | Toyo Shinyaku:Kk | 持久力向上用食品組成物 |
| TWI330529B (en) * | 2003-01-13 | 2010-09-21 | Horphag Res Luxembourg Holding Sa | A preparation for improving sperm quality or fertility,a kit comprising the same and uses thereof |
| US20080089962A1 (en) * | 2004-09-24 | 2008-04-17 | Multi Formulations Ltd. | Nutritional composition for facilitating muscle pumps |
| US20050256192A1 (en) * | 2004-04-30 | 2005-11-17 | Gardiner Paul T | Nutritional composition for enhancing lean muscle stimulus, growth, strength and recovery, creating and prolonging intense muscle pumps, supporting endurance, strength, performance, size and stamina, providing a transducer effect for nitric oxide, increasing nutrient delivery and/or promoting increased vascular response in an individual |
| HUP0401422A2 (en) | 2004-07-15 | 2006-04-28 | G Laszlo Meszaros | Use of l-arginine as vasoaktive ingredient absorbing through skin for external application |
| JP2010163426A (ja) * | 2008-12-18 | 2010-07-29 | Daiichi Sankyo Healthcare Co Ltd | ホスホジエステラーゼ5阻害剤とアルギニンを含有する医薬組成物 |
| JP5819951B2 (ja) * | 2010-06-25 | 2015-11-24 | ホーファグ リサーチ (アイピー) ピーアールイー リミテッド | セクシャルウェルネスを改善するための組成物 |
| IT1402672B1 (it) * | 2010-11-08 | 2013-09-13 | Medestea Biotech S P A | Composizioni comprendenti principi attivi di origine vegetale associati o meno a promotori e/o protettori di ossido nitrico per il trattamento e la prevenzione dei deficit erettili e dell' impotenza e per il potenziamento della performance sportiva |
| RU2458537C1 (ru) * | 2011-03-14 | 2012-08-20 | Общество С Ограниченной Ответственностью "Парафарм" | Биологически активная добавка к пище для профилактики эректильной дисфункции у мужчин |
| JP2014156429A (ja) * | 2013-02-15 | 2014-08-28 | Toyo Shinyaku Co Ltd | エンドセリン受容体発現抑制剤 |
| LT6262B (lt) | 2014-05-16 | 2016-04-25 | Uab "Ekologiå Ka Energija" | Tonizuojantis gėrimas moterims ir vyrams |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
| WO2020165917A1 (en) * | 2019-02-11 | 2020-08-20 | Olene Life Sciences Private Limited | A synergistic herbal composition for sexual disorders |
| JP2020164495A (ja) * | 2019-03-29 | 2020-10-08 | 株式会社東洋新薬 | 男性活力用組成物及び組成物 |
| PL4164629T3 (pl) * | 2020-06-18 | 2024-11-18 | Horphag Research Ip (Pyc) Ltd. | Procyjanidyny do leczenia zaburzenia czynności śródbłonka spowodowanego przez COVID-19 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| US5891459A (en) * | 1993-06-11 | 1999-04-06 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
| US5695761A (en) * | 1993-12-23 | 1997-12-09 | Rutgers University | Suppression of nitric oxide production by osteopontin |
| US6297273B1 (en) * | 1996-04-02 | 2001-10-02 | Mars, Inc. | Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions |
| US6469053B1 (en) * | 1996-04-02 | 2002-10-22 | Mars Incorporated | Use of procyanidins in the maintenance of vascular health and modulation of the inflammatory response |
| US6423743B1 (en) * | 1996-04-02 | 2002-07-23 | Mars Incorporated | Cocoa extract compounds and methods for making and using the same |
| US5720956A (en) | 1996-04-10 | 1998-02-24 | Rohdewald; Peter | Method of controlling the reactivity of human blood platelets by oral administration of the extract of the maritime pine (pycnogenol) |
| US6558713B2 (en) * | 1996-09-06 | 2003-05-06 | Mars, Incorporated | Health of a mammal by administering a composition containing at least one cocoa polyphenol ingredient |
| FR2765483B1 (fr) * | 1997-07-04 | 2000-02-04 | Philippe Gorny | Medicament destine a traiter les dysfonctions erectiles |
| AU751182B2 (en) * | 1997-12-02 | 2002-08-08 | Archimedes Development Limited | Compositions for nasal administration |
| EP1894566A1 (en) * | 1998-03-12 | 2008-03-05 | Mars, Incorporated | Products containing polyphenol(s) and L-arginine to stimulate nitric oxide production |
| US8507018B2 (en) * | 1998-03-12 | 2013-08-13 | Mars, Incorporated | Products containing polyphenol(s) and L-arginine and methods of use thereof |
| US6007824A (en) * | 1998-07-09 | 1999-12-28 | Duckett; Melvin J. | Natural composition and method for the treatment of sexual dysfunction |
| DE19845314B4 (de) | 1998-10-01 | 2008-01-17 | Horphag Research (Luxembourg) Holding Sa | Procyanidinhaltiges Mittel zur Behandlung von erektiler Dysfunktion |
| JP3260134B2 (ja) * | 1999-10-08 | 2002-02-25 | 信孝 鈴木 | 月経困難症、子宮内膜症の治療薬 |
| WO2001078529A2 (en) * | 2000-04-14 | 2001-10-25 | Mars, Incorporated | Compositions and methods for improving vascular health |
| AU2001282373A1 (en) * | 2000-05-26 | 2001-12-03 | Horphag Research Limited | Use of proanthocyanidins as an active ingredient of a stimulator and l-arginine or its salts as a source of nitric oxide to relieve symptoms of erectile dysfuntion |
| US6706756B1 (en) * | 2001-11-16 | 2004-03-16 | University Of South Florida | Vasodilating compound and method of use |
-
2001
- 2001-05-24 AU AU2001282373A patent/AU2001282373A1/en not_active Abandoned
- 2001-05-24 US US09/865,189 patent/US6565851B2/en not_active Expired - Lifetime
- 2001-05-24 JP JP2001585787A patent/JP2003534286A/ja active Pending
- 2001-05-24 WO PCT/IB2001/000910 patent/WO2001089543A2/en not_active Ceased
-
2003
- 2003-01-13 US US10/340,994 patent/US20030104077A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6565851B2 (en) | 2003-05-20 |
| US20030104077A1 (en) | 2003-06-05 |
| US20020037862A1 (en) | 2002-03-28 |
| WO2001089543A2 (en) | 2001-11-29 |
| JP2003534286A (ja) | 2003-11-18 |
| WO2001089543A3 (en) | 2002-10-03 |
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