AU2001278471A1 - Stable salts of o-acetylsalicyclic with basic amino acids - Google Patents

Stable salts of o-acetylsalicyclic with basic amino acids

Info

Publication number
AU2001278471A1
AU2001278471A1 AU2001278471A AU2001278471A AU2001278471A1 AU 2001278471 A1 AU2001278471 A1 AU 2001278471A1 AU 2001278471 A AU2001278471 A AU 2001278471A AU 2001278471 A AU2001278471 A AU 2001278471A AU 2001278471 A1 AU2001278471 A1 AU 2001278471A1
Authority
AU
Australia
Prior art keywords
acetylsalicyclic
amino acids
basic amino
stable salts
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001278471A
Other versions
AU2001278471B2 (en
Inventor
Hubert Appolt
Gerhard Franckowiak
Wolfram Ledwoch
Gregor Leifker
Hans-Peter Wirges
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10034802A external-priority patent/DE10034802A1/en
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of AU2001278471A1 publication Critical patent/AU2001278471A1/en
Application granted granted Critical
Publication of AU2001278471B2 publication Critical patent/AU2001278471B2/en
Assigned to BAYER HEALTHCARE AG reassignment BAYER HEALTHCARE AG Request for Assignment Assignors: BAYER ATKIENGESELLSCHAFT
Priority to AU2004218728A priority Critical patent/AU2004218728B8/en
Assigned to BAYER SCHERING PHARMA AKTIENGESELLSCHAFT reassignment BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Request for Assignment Assignors: BAYER HEALTHCARE AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2001278471A 2000-07-18 2001-07-05 Stable salts of o-acetylsalicyclic with basic amino acids Ceased AU2001278471B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2004218728A AU2004218728B8 (en) 2000-07-18 2004-10-13 Stable salts of O-acetylsalicyclic acid with basic amino acids

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10034802A DE10034802A1 (en) 2000-07-18 2000-07-18 Stable salts of O-acetylsalicylic acid with basic amino acids
DE10034802.5 2000-07-18
PCT/EP2001/007669 WO2002005782A2 (en) 2000-07-18 2001-07-05 Stable salts of o-acetylsalicyclic with basic amino acids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2004218728A Division AU2004218728B8 (en) 2000-07-18 2004-10-13 Stable salts of O-acetylsalicyclic acid with basic amino acids

Publications (2)

Publication Number Publication Date
AU2001278471A1 true AU2001278471A1 (en) 2002-05-02
AU2001278471B2 AU2001278471B2 (en) 2004-07-22

Family

ID=7649258

Family Applications (2)

Application Number Title Priority Date Filing Date
AU7847101A Pending AU7847101A (en) 2000-07-18 2001-07-05 Stable salts of o-acetylsalicyclic with basic amino acids
AU2001278471A Ceased AU2001278471B2 (en) 2000-07-18 2001-07-05 Stable salts of o-acetylsalicyclic with basic amino acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU7847101A Pending AU7847101A (en) 2000-07-18 2001-07-05 Stable salts of o-acetylsalicyclic with basic amino acids

Country Status (34)

Country Link
US (2) US6773724B2 (en)
EP (1) EP1365737B1 (en)
JP (2) JP2004507463A (en)
KR (1) KR100773658B1 (en)
CN (1) CN1205176C (en)
AR (1) AR030305A1 (en)
AT (1) ATE293589T1 (en)
AU (2) AU7847101A (en)
BR (1) BR0112538A (en)
CA (1) CA2416288C (en)
CR (1) CR6888A (en)
CZ (1) CZ300337B6 (en)
DE (2) DE10034802A1 (en)
DK (1) DK1365737T3 (en)
EC (1) ECSP034437A (en)
ES (1) ES2241849T3 (en)
GT (1) GT200100134A (en)
HK (1) HK1061811A1 (en)
HR (1) HRP20030108B1 (en)
HU (1) HUP0302053A3 (en)
IL (2) IL153873A0 (en)
MX (1) MXPA03000510A (en)
MY (1) MY134521A (en)
NO (1) NO20030222D0 (en)
PE (1) PE20020267A1 (en)
PL (1) PL204593B1 (en)
PT (1) PT1365737E (en)
RS (1) RS50329B (en)
SK (1) SK286162B6 (en)
SV (1) SV2002000557A (en)
TW (1) TWI299729B (en)
UY (1) UY26841A1 (en)
WO (1) WO2002005782A2 (en)
ZA (1) ZA200300469B (en)

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US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
DE10202019A1 (en) * 2002-01-18 2003-07-24 Bayer Ag Pharmaceutical composition, useful in oral formulations for the treatment of e.g. rheumatism, neuralgia, migraine or myocardial infarction, comprises a free-flowing salt of acetylsalicylic acid and a basic amino acid
US8142810B2 (en) 2002-05-30 2012-03-27 The Procter & Gamble Company Dietary method for modulating glucose metabolism and associated conditions and increasing longevity
ATE442352T1 (en) * 2003-05-16 2009-09-15 Cephalon France METHOD FOR PRODUCING MODAFINIL
EP1778652A2 (en) * 2004-08-20 2007-05-02 EntreMed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
US20060166901A1 (en) * 2005-01-03 2006-07-27 Yu Ruey J Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids
DE102005025283A1 (en) * 2005-06-02 2006-12-07 Bayer Healthcare Ag Stable complex of salts of o-acetylsalicylic acid with basic amino acids and glycine
DE102005049293A1 (en) * 2005-10-15 2007-04-26 Bayer Healthcare Ag Combination preparations of salts or o-acetylsalicylic acid
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
WO2008007171A1 (en) 2006-07-09 2008-01-17 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
CN105820107B (en) * 2007-06-04 2022-09-09 泰飞尔公司 Prodrug of non-steroidal anti-inflammatory drug with rapid skin and biological membrane penetration speed and novel medical application thereof
DE102008004386A1 (en) * 2008-01-14 2009-07-23 Activaero Gmbh Use of an acetylsalicylic acid salt for the treatment of viral infections
CN101314029B (en) * 2008-06-18 2010-12-08 四川省农业科学院实验场 Acetylsalicylic peptide and preparation method thereof
WO2010056919A2 (en) * 2008-11-12 2010-05-20 Kyphia Pharmaceuticals, Inc. Eflornithine prodrugs, conjugates and salts, and methods of use thereof
KR20200022525A (en) 2008-12-04 2020-03-03 충시 위 High Penetration Compositions and Their Applications
BRPI1009600A2 (en) * 2009-06-25 2016-03-22 Tetra S A
CN101633624B (en) * 2009-08-04 2013-05-01 蚌埠丰原医药科技发展有限公司 Preparation method of improved di-lysine-aspirin
FR2950625B1 (en) * 2009-09-30 2016-12-02 Holis Tech PROCESS FOR PREPARING AN O-ACETYLSALICYL ACID SALT OF A BASIC AMINO ACID AND COMPOSITION OBTAINED
FR2965261B1 (en) * 2009-09-30 2012-10-26 Holis Technologies PROCESS FOR THE PREPARATION OF AN O-ACETYLSALICYLIC ACID SALT OF A BASIC AMINO ACID AND COMPOSITION OBTAINED THEREBY
FR2973370B1 (en) * 2011-03-29 2013-05-03 Holis Technologies LOW COST PROCESS FOR THE PREPARATION OF O-ACETYLSALICYCLIC ACID AND BASIC AMINO ACID
CN102503845A (en) * 2011-09-28 2012-06-20 广州普星药业有限公司 Preparation method of DL-lysine aspirin salt and application thereof
IN2014KN02583A (en) 2012-05-16 2015-05-08 Techfields Pharma Co Ltd
CN102976962B (en) * 2012-11-20 2015-02-04 南京工业大学 L-ornithine-aspirin double salt and its preparation method and use
FR3021654B1 (en) 2014-05-28 2016-06-24 Unither Pharmaceuticals PROCESS FOR THE PREPARATION OF AN ACETYLSALICYLIC ACID SALT AND A BASIC AMINO ACID
AU2017383071B2 (en) * 2016-12-23 2021-04-29 Aspiair Gmbh Improved synthesis of lysine acetylsalicylate · glycine particles
CN110996965A (en) 2017-05-30 2020-04-10 罗山制药股份有限公司 Stable, sterile and crystalline in-vial deposits of ortho-acetylsalicylic acid (aspirin)
KR20200035047A (en) * 2017-08-03 2020-04-01 산텐 세이야꾸 가부시키가이샤 Pharmaceutical composition containing chlorhexidine
CN113105326A (en) * 2021-03-24 2021-07-13 海南卓华制药有限公司 Preparation method and application of aspirin lysine
CN114478287A (en) * 2021-12-31 2022-05-13 蚌埠丰原医药科技发展有限公司 Aspirin-lysine crystal form, preparation method and application
CA3239851A1 (en) 2022-01-05 2023-07-13 Karlheinz Nocker Improved synthesis of lysine acetylsalicylate · glycine particles

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
FR2115060A1 (en) * 1970-11-26 1972-07-07 Metabio Freeze-dried acetylsalicylates of lysine and arginine - easily prepd derivs of aspirin
ES388158A1 (en) * 1971-02-11 1974-03-16 Liade Sa Lab Procedure for obtaining soluble salts from salicy acetyl acid. (Machine-translation by Google Translate, not legally binding)
JPS4856815A (en) * 1971-11-13 1973-08-09
JPS55127345A (en) * 1979-03-23 1980-10-02 Kyowa Hakko Kogyo Co Ltd Preparation of acetylsalicylic acid salt
JPS5610110A (en) * 1979-07-06 1981-02-02 Green Cross Corp:The Acetyl salicylate salt preparation for injection
JPS56113741A (en) * 1980-02-13 1981-09-07 Mitsui Toatsu Chem Inc Preparation of crystal of acetylsalicylic acid salt
JPS5721345A (en) * 1980-07-15 1982-02-04 Mitsui Toatsu Chem Inc Purification of acetylsalicylate salt
CS247688B1 (en) * 1984-12-22 1987-01-15 Evzen Kasafirek Method of lysine salt with acetylsalicylid acid production
JPS632929A (en) * 1986-06-20 1988-01-07 Kao Corp Acetylsalicylic acid drug preparation
EP0499142A3 (en) * 1991-02-09 1993-05-05 Hoechst Aktiengesellschaft Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non steroidal anti-flammatory drugs
DE4332093C2 (en) * 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermal therapeutic system with the active ingredient acetylsalicylic acid and process for its preparation

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