AU2001249322B2 - Ligament replacement constructs and methods for production and use thereof - Google Patents
Ligament replacement constructs and methods for production and use thereof Download PDFInfo
- Publication number
- AU2001249322B2 AU2001249322B2 AU2001249322A AU2001249322A AU2001249322B2 AU 2001249322 B2 AU2001249322 B2 AU 2001249322B2 AU 2001249322 A AU2001249322 A AU 2001249322A AU 2001249322 A AU2001249322 A AU 2001249322A AU 2001249322 B2 AU2001249322 B2 AU 2001249322B2
- Authority
- AU
- Australia
- Prior art keywords
- cells
- ligament
- acl
- matrix
- fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000000034 method Methods 0.000 title claims abstract description 27
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 239000000835 fiber Substances 0.000 claims abstract description 49
- 239000000463 material Substances 0.000 claims abstract description 14
- 230000008439 repair process Effects 0.000 claims abstract description 12
- 210000004027 cell Anatomy 0.000 claims description 49
- 210000001264 anterior cruciate ligament Anatomy 0.000 claims description 35
- 239000011159 matrix material Substances 0.000 claims description 28
- 238000009954 braiding Methods 0.000 claims description 16
- 238000003306 harvesting Methods 0.000 claims description 4
- 210000002435 tendon Anatomy 0.000 claims description 4
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- 208000025674 Anterior Cruciate Ligament injury Diseases 0.000 description 2
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- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
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- NHBKXEKEPDILRR-UHFFFAOYSA-N 2,3-bis(butanoylsulfanyl)propyl butanoate Chemical compound CCCC(=O)OCC(SC(=O)CCC)CSC(=O)CCC NHBKXEKEPDILRR-UHFFFAOYSA-N 0.000 description 1
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- 102000029816 Collagenase Human genes 0.000 description 1
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- MKXKFYHWDHIYRV-UHFFFAOYSA-N flutamide Chemical compound CC(C)C(=O)NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1 MKXKFYHWDHIYRV-UHFFFAOYSA-N 0.000 description 1
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- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
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- 238000011587 new zealand white rabbit Methods 0.000 description 1
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- 210000000426 patellar ligament Anatomy 0.000 description 1
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Lining Or Joining Of Plastics Or The Like (AREA)
- Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19199900P | 2000-03-24 | 2000-03-24 | |
| US60/191,999 | 2000-03-24 | ||
| PCT/US2001/009079 WO2001072241A1 (en) | 2000-03-24 | 2001-03-22 | Ligament replacement constructs and methods for production and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2001249322A1 AU2001249322A1 (en) | 2001-12-20 |
| AU2001249322B2 true AU2001249322B2 (en) | 2004-10-14 |
Family
ID=22707811
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001249322A Ceased AU2001249322B2 (en) | 2000-03-24 | 2001-03-22 | Ligament replacement constructs and methods for production and use thereof |
| AU4932201A Pending AU4932201A (en) | 2000-03-24 | 2001-03-22 | Ligament replacement constructs and methods for production and use thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU4932201A Pending AU4932201A (en) | 2000-03-24 | 2001-03-22 | Ligament replacement constructs and methods for production and use thereof |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1272127B1 (enExample) |
| JP (2) | JP4452426B2 (enExample) |
| AT (1) | ATE381912T1 (enExample) |
| AU (2) | AU2001249322B2 (enExample) |
| CA (1) | CA2403983C (enExample) |
| DE (1) | DE60132079T2 (enExample) |
| DK (1) | DK1272127T3 (enExample) |
| ES (1) | ES2299481T3 (enExample) |
| WO (1) | WO2001072241A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8486143B2 (en) | 2009-05-22 | 2013-07-16 | Soft Tissue Regeneration, Inc. | Mechanically competent scaffold for ligament and tendon regeneration |
| US8945218B2 (en) | 2000-03-24 | 2015-02-03 | Drexel University | Ligament and tendon replacement constructs and methods for production and use thereof |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030212456A1 (en) * | 2002-05-09 | 2003-11-13 | John Lipchitz | Implant for tissue repair |
| US8177839B2 (en) * | 2006-12-27 | 2012-05-15 | Shriners Hospitals For Children | Woven and/or braided fiber implants and methods of making same |
| EP2131880B1 (en) | 2007-02-20 | 2012-08-08 | Shriners Hospitals for Children | In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers |
| JP5492097B2 (ja) | 2008-02-22 | 2014-05-14 | マイメディクス，インコーポレイテッド | 手首、手及びその他の靱帯置換術又は修復術のために適切なバイオステープル |
| EP2291143B1 (en) | 2008-05-16 | 2020-07-08 | Mimedx, Inc. | Medical constructs of twisted lengths of collagen fibers and methods of making same |
| CA2740008C (en) | 2008-10-09 | 2017-01-31 | Mimedx, Inc. | Methods of making biocomposite medical constructs and related constructs including artificial tissues, vessels and patches |
| US9757132B2 (en) * | 2010-03-24 | 2017-09-12 | Biorez, Inc. | Mechanically competent scaffold for rotator cuff and tendon augmentation |
| CA2829339C (en) | 2011-03-08 | 2018-10-16 | Mimedx, Inc. | Collagen fiber ribbons with integrated fixation sutures and methods of making the same |
| US9694106B2 (en) | 2011-07-11 | 2017-07-04 | Mimedx Group, Inc. | Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods |
| US8986378B2 (en) | 2011-11-02 | 2015-03-24 | Mimedx Group, Inc. | Implantable collagen devices and related methods and systems of making same |
| US9433489B2 (en) | 2013-03-12 | 2016-09-06 | Soft Tissue Regeneration, Inc. | Absorbable synthetic braided matrix for breast reconstruction and hernia repair |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376118A (en) * | 1989-05-10 | 1994-12-27 | United States Surgical Corporation | Support material for cell impregnation |
| WO1995001810A1 (en) * | 1993-07-07 | 1995-01-19 | Smith & Nephew Plc | Implantable prosthesis, kit and device for manufacturing the same |
| WO1997045147A1 (en) * | 1996-05-28 | 1997-12-04 | 1218122 Ontario Inc. | Resorbable implant biomaterial made of condensed calcium phosphate particles |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4792336A (en) * | 1986-03-03 | 1988-12-20 | American Cyanamid Company | Flat braided ligament or tendon implant device having texturized yarns |
| US5263984A (en) * | 1987-07-20 | 1993-11-23 | Regen Biologics, Inc. | Prosthetic ligaments |
| EP0306018A1 (en) * | 1987-09-04 | 1989-03-08 | Bio-Products, Inc. | Tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers |
| US5078744A (en) * | 1987-09-04 | 1992-01-07 | Bio-Products, Inc. | Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers |
| EP0677297B1 (en) * | 1993-09-24 | 2000-12-13 | Takiron Co. Ltd. | Implantation material |
| GB2282328B (en) * | 1993-09-29 | 1997-10-08 | Johnson & Johnson Medical | Absorbable structures for ligament and tendon repair |
| JPH10505250A (ja) * | 1994-06-06 | 1998-05-26 | ケース ウエスターン リザーブ ユニバーシティ | 組織再生のためのバイオマトリックス |
| US5718012A (en) * | 1996-05-28 | 1998-02-17 | Organogenesis, Inc. | Method of strength enhancement of collagen constructs |
-
2001
- 2001-03-22 EP EP01922531A patent/EP1272127B1/en not_active Expired - Lifetime
- 2001-03-22 WO PCT/US2001/009079 patent/WO2001072241A1/en not_active Ceased
- 2001-03-22 DK DK01922531T patent/DK1272127T3/da active
- 2001-03-22 AT AT01922531T patent/ATE381912T1/de active
- 2001-03-22 AU AU2001249322A patent/AU2001249322B2/en not_active Ceased
- 2001-03-22 CA CA002403983A patent/CA2403983C/en not_active Expired - Lifetime
- 2001-03-22 DE DE60132079T patent/DE60132079T2/de not_active Expired - Lifetime
- 2001-03-22 ES ES01922531T patent/ES2299481T3/es not_active Expired - Lifetime
- 2001-03-22 AU AU4932201A patent/AU4932201A/xx active Pending
- 2001-03-22 JP JP2001570204A patent/JP4452426B2/ja not_active Expired - Fee Related
-
2007
- 2007-06-20 JP JP2007161999A patent/JP4897583B2/ja not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376118A (en) * | 1989-05-10 | 1994-12-27 | United States Surgical Corporation | Support material for cell impregnation |
| WO1995001810A1 (en) * | 1993-07-07 | 1995-01-19 | Smith & Nephew Plc | Implantable prosthesis, kit and device for manufacturing the same |
| WO1997045147A1 (en) * | 1996-05-28 | 1997-12-04 | 1218122 Ontario Inc. | Resorbable implant biomaterial made of condensed calcium phosphate particles |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945218B2 (en) | 2000-03-24 | 2015-02-03 | Drexel University | Ligament and tendon replacement constructs and methods for production and use thereof |
| US8486143B2 (en) | 2009-05-22 | 2013-07-16 | Soft Tissue Regeneration, Inc. | Mechanically competent scaffold for ligament and tendon regeneration |
| US8758437B2 (en) | 2009-05-22 | 2014-06-24 | Soft Tissue Regeneration, Inc. | Mechanically competent scaffold for ligament and tendon regeneration |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2403983C (en) | 2008-02-12 |
| WO2001072241A1 (en) | 2001-10-04 |
| DK1272127T3 (da) | 2008-04-28 |
| EP1272127B1 (en) | 2007-12-26 |
| DE60132079D1 (de) | 2008-02-07 |
| JP4897583B2 (ja) | 2012-03-14 |
| CA2403983A1 (en) | 2001-10-04 |
| JP4452426B2 (ja) | 2010-04-21 |
| DE60132079T2 (de) | 2008-12-18 |
| JP2007289727A (ja) | 2007-11-08 |
| EP1272127A4 (en) | 2004-03-03 |
| EP1272127A1 (en) | 2003-01-08 |
| AU4932201A (en) | 2001-10-08 |
| ES2299481T3 (es) | 2008-06-01 |
| JP2003530912A (ja) | 2003-10-21 |
| ATE381912T1 (de) | 2008-01-15 |
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| Tsonis | Ankle Surgery |
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