AU2001247224A1 - 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents - Google Patents

4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents

Info

Publication number
AU2001247224A1
AU2001247224A1 AU2001247224A AU4722401A AU2001247224A1 AU 2001247224 A1 AU2001247224 A1 AU 2001247224A1 AU 2001247224 A AU2001247224 A AU 2001247224A AU 4722401 A AU4722401 A AU 4722401A AU 2001247224 A1 AU2001247224 A1 AU 2001247224A1
Authority
AU
Australia
Prior art keywords
methyl
oxo
chlorobenzyl
dihydro
cinnolinecarboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001247224A
Other languages
English (en)
Inventor
Scott D. Larsen
Sajiv K. Nair
Valerie A Vaillancourt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co LLC
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU2001247224A1 publication Critical patent/AU2001247224A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28Cinnolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001247224A 2000-03-21 2001-03-15 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents Abandoned AU2001247224A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19129100P 2000-03-21 2000-03-21
US60191291 2000-03-21
PCT/US2001/005811 WO2001070706A2 (en) 2000-03-21 2001-03-15 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents

Publications (1)

Publication Number Publication Date
AU2001247224A1 true AU2001247224A1 (en) 2001-10-03

Family

ID=22704885

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001247224A Abandoned AU2001247224A1 (en) 2000-03-21 2001-03-15 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents

Country Status (28)

Country Link
US (1) US6624160B2 (zh)
EP (1) EP1265873B1 (zh)
JP (1) JP2003528087A (zh)
KR (1) KR20020081479A (zh)
CN (1) CN1406228A (zh)
AR (1) AR027978A1 (zh)
AT (1) ATE252086T1 (zh)
AU (1) AU2001247224A1 (zh)
BR (1) BR0109487A (zh)
CA (1) CA2400000A1 (zh)
CZ (1) CZ20023141A3 (zh)
DE (1) DE60100999T2 (zh)
DK (1) DK1265873T3 (zh)
EA (1) EA200201002A1 (zh)
EE (1) EE200200541A (zh)
ES (1) ES2208581T3 (zh)
HK (1) HK1052694A1 (zh)
HU (1) HUP0300326A3 (zh)
IL (1) IL151787A0 (zh)
MX (1) MXPA02009251A (zh)
NO (1) NO20024502L (zh)
NZ (1) NZ521524A (zh)
PL (1) PL357443A1 (zh)
PT (1) PT1265873E (zh)
SI (1) SI1265873T1 (zh)
SK (1) SK12102002A3 (zh)
WO (1) WO2001070706A2 (zh)
ZA (1) ZA200207540B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011349A1 (es) * 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
WO2014070976A1 (en) * 2012-11-03 2014-05-08 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
KR20230170813A (ko) 2018-09-12 2023-12-19 노파르티스 아게 항바이러스 피리도피라진디온 화합물
US11667613B2 (en) 2019-09-26 2023-06-06 Novartis Ag Antiviral pyrazolopyridinone compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8513639D0 (en) 1985-05-30 1985-07-03 Ici America Inc Cinnoline compounds
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides
ATE239477T1 (de) 1995-08-02 2003-05-15 Darwin Discovery Ltd Chinolone und deren therapeutische verwendung
CA2225555A1 (en) 1995-08-02 1997-02-13 Chiroscience Limited Quinolones and their therapeutic use
NZ505362A (en) 1997-12-22 2004-12-24 Upjohn Co 4-hydroxyquinoline-3-carboxamides and -hydrazides useful as antiviral agents
WO1999038867A1 (fr) 1998-01-29 1999-08-05 Suntory Limited Derives de 1-cycloalkyle-1,8-naphthyridine-4-one presentant une activite inhibitrice de la phosphodiesterase iv

Also Published As

Publication number Publication date
PT1265873E (pt) 2004-03-31
CN1406228A (zh) 2003-03-26
WO2001070706A2 (en) 2001-09-27
US20020045619A1 (en) 2002-04-18
ES2208581T3 (es) 2004-06-16
EE200200541A (et) 2004-04-15
CZ20023141A3 (cs) 2003-02-12
NZ521524A (en) 2004-04-30
HUP0300326A3 (en) 2003-09-29
PL357443A1 (en) 2004-07-26
SI1265873T1 (en) 2004-02-29
DK1265873T3 (da) 2004-02-16
ZA200207540B (en) 2003-12-19
HUP0300326A2 (hu) 2003-07-28
JP2003528087A (ja) 2003-09-24
US6624160B2 (en) 2003-09-23
EP1265873B1 (en) 2003-10-15
HK1052694A1 (zh) 2003-09-26
DE60100999D1 (en) 2003-11-20
NO20024502L (no) 2002-11-20
WO2001070706A3 (en) 2002-05-10
IL151787A0 (en) 2003-04-10
CA2400000A1 (en) 2001-09-27
SK12102002A3 (sk) 2003-03-04
KR20020081479A (ko) 2002-10-26
ATE252086T1 (de) 2003-11-15
DE60100999T2 (de) 2004-09-02
AR027978A1 (es) 2003-04-23
EA200201002A1 (ru) 2003-02-27
MXPA02009251A (es) 2004-04-05
NO20024502D0 (no) 2002-09-20
BR0109487A (pt) 2003-06-10
EP1265873A2 (en) 2002-12-18

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