AU2001227755A1 - Inhibitors of prenyl-protein transferase - Google Patents

Inhibitors of prenyl-protein transferase

Info

Publication number
AU2001227755A1
AU2001227755A1 AU2001227755A AU2775501A AU2001227755A1 AU 2001227755 A1 AU2001227755 A1 AU 2001227755A1 AU 2001227755 A AU2001227755 A AU 2001227755A AU 2775501 A AU2775501 A AU 2775501A AU 2001227755 A1 AU2001227755 A1 AU 2001227755A1
Authority
AU
Australia
Prior art keywords
prenyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001227755A
Other languages
English (en)
Inventor
S. Jane Desolms
Suzanne C. Mactough
Anthony W. Shaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001227755A1 publication Critical patent/AU2001227755A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001227755A 2000-01-12 2001-01-09 Inhibitors of prenyl-protein transferase Abandoned AU2001227755A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17570800P 2000-01-12 2000-01-12
US60175708 2000-01-12
PCT/US2001/000632 WO2001051125A1 (fr) 2000-01-12 2001-01-09 Inhibiteurs de la prenyl-proteine transferase

Publications (1)

Publication Number Publication Date
AU2001227755A1 true AU2001227755A1 (en) 2001-07-24

Family

ID=22641313

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001227755A Abandoned AU2001227755A1 (en) 2000-01-12 2001-01-09 Inhibitors of prenyl-protein transferase

Country Status (3)

Country Link
US (1) US6413964B1 (fr)
AU (1) AU2001227755A1 (fr)
WO (1) WO2001051125A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2210612B1 (fr) 2003-06-18 2016-10-05 Ocera Therapeutics, Inc. Antagonistes macrocycliques du récepteur de motiline
US8921533B2 (en) 2011-07-25 2014-12-30 Chromatin Technologies Glycosylated valproic acid analogs and uses thereof
MA39823A (fr) * 2014-04-03 2018-01-09 Janssen Pharmaceutica Nv Dérivés de pyridine macrocyclique
CN109053525B (zh) * 2018-09-25 2020-05-05 成都福柯斯医药技术有限公司 一种(r)-2-(2-取代-5-氟苯)吡咯烷的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000497A1 (fr) 1993-06-18 1995-01-05 Merck & Co., Inc. Inhibiteurs de farnesyle-proteine transferase
WO1995008542A1 (fr) 1993-09-22 1995-03-30 Kyowa Hakko Kogyo Co., Ltd. Inhibiteur de la farnesyl-transferase
US5856326A (en) 1995-03-29 1999-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5756528A (en) 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5859012A (en) 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5919785A (en) 1996-04-03 1999-07-06 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5859015A (en) 1996-04-03 1999-01-12 Merck & Co., Inc. N-heterocyclic piperazinyl and H-heterocyclic piperazinonyl inhibitors of farnesyl-protein transferase
US5885995A (en) 1996-04-03 1999-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
CA2301770A1 (fr) 1997-08-27 1999-03-04 Merck & Co., Inc. Inhibiteurs de prenyl-proteine-transferases
AU9695198A (en) 1997-10-17 1999-05-10 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP2002519376A (ja) 1998-07-02 2002-07-02 メルク エンド カムパニー インコーポレーテッド プレニル蛋白トランスフェラーゼ阻害薬
WO2000001701A1 (fr) 1998-07-02 2000-01-13 Merck & Co., Inc. Inhibiteurs de prenyl-proteine transferase
CA2336475A1 (fr) 1998-07-02 2000-01-13 Christopher J. Dinsmore Inhibiteurs de prenyl-proteine transferase

Also Published As

Publication number Publication date
WO2001051125A1 (fr) 2001-07-19
US6413964B1 (en) 2002-07-02

Similar Documents

Publication Publication Date Title
AU2001243158A1 (en) Inhibitors of prenyl-protein transferase
EP1324985A4 (fr) Inhibiteurs de la prenyl-proteine transferase
EP1087770A4 (fr) Inhibiteurs de prenyl-proteine transferase
EP1165082A4 (fr) Inhibiteurs de la prenyle-proteine transferase
AU2001241927A1 (en) Inhibitors of p38-alpha kinase
AU2002213485A1 (en) Inhibitors of protein kinases
AU2001237041A1 (en) Kinase inhibitors
EP1165084A4 (fr) Inhibiteurs de prenyl-proteine transferases
AU2001238217A1 (en) Inhibitors of prenyl-protein transferase
EP1091736A4 (fr) Inhibiteurs de prenyl-proteine transferase
AU2001247197A1 (en) Inhibitors of prenyl-protein transferase
AU7354900A (en) Inhibitors of prenyl-protein transferase
AU2477400A (en) Inhibitors of prenyl-protein transferase
AU2001227757A1 (en) Inhibitors of prenyl-protein transferase
AU2001238424A1 (en) Inhibitors of prenyl-protein transferase
AU2274101A (en) Inhibitors of prenyl-protein transferase
EP1158982A4 (fr) Inhibiteurs de la prenyle-proteine transferase
AU2002237657A1 (en) Indole-type inhibitors of p38 kinase
AU2001230864A1 (en) Inhibitors of prenyl-protein transferase
AU2001229320A1 (en) Inhibitors of prenyl-protein transferase
AU2001227756A1 (en) Inhibitors of prenyl-protein transferase
AU2002214038A1 (en) Inhibitors of transglutaminases
AU2002254375A1 (en) Inhibitors of prenyl-protein transferase
AU2001251445A1 (en) Inhibitors of prenyl-protein transferase
AU2478500A (en) Inhibitors of prenyl-protein transferase