AU2000263274A1 - Synergistic compositions containing choline base and succinic acid for insulin resistance and diabetes - Google Patents
Synergistic compositions containing choline base and succinic acid for insulin resistance and diabetesInfo
- Publication number
- AU2000263274A1 AU2000263274A1 AU2000263274A AU6327400A AU2000263274A1 AU 2000263274 A1 AU2000263274 A1 AU 2000263274A1 AU 2000263274 A AU2000263274 A AU 2000263274A AU 6327400 A AU6327400 A AU 6327400A AU 2000263274 A1 AU2000263274 A1 AU 2000263274A1
- Authority
- AU
- Australia
- Prior art keywords
- diabetes
- succinic acid
- compositions containing
- insulin resistance
- synergistic compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 title 2
- 206010022489 Insulin Resistance Diseases 0.000 title 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 title 1
- 229960001231 choline Drugs 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000001384 succinic acid Substances 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU2000/000122 WO2001076583A1 (en) | 2000-04-10 | 2000-04-10 | Synergistic compositions containing choline base and succinic acid for insulin resistance and diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2000263274A1 true AU2000263274A1 (en) | 2001-10-23 |
Family
ID=20129496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2000263274A Abandoned AU2000263274A1 (en) | 2000-04-10 | 2000-04-10 | Synergistic compositions containing choline base and succinic acid for insulin resistance and diabetes |
Country Status (8)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004112773A1 (fr) * | 2003-04-24 | 2004-12-29 | Shin-Jen Shiao | Compositions pharmaceutiques utilisees pour le traitement de maladie immune et amelioration |
| KR20100031760A (ko) * | 2007-08-02 | 2010-03-24 | 부다 바이오파마 오와이 리미티드 | 숙신산의 콜린염을 포함하는 비강내 투여용 약학 조성물 |
| KR101360569B1 (ko) | 2008-11-26 | 2014-02-10 | 이고르 아나토리에비치 포밋트킨 | 우울증, 불안증, 정신분열증, 수면장애 및 간질의 치료를 위한 숙신산의 콜린염 |
| US8314080B2 (en) | 2010-04-06 | 2012-11-20 | Kuwait University | Method of treating type I diabetes |
| CN106727476A (zh) * | 2016-12-09 | 2017-05-31 | 杨远志 | 一种组合物及其在改善动物肌纤维类型中的应用 |
| WO2024231663A1 (en) | 2023-05-05 | 2024-11-14 | Mitocholine Ltd | Method of synthesis |
| WO2025163212A2 (en) | 2024-08-09 | 2025-08-07 | Jantar Gmbh | Succinic acid or a pharmaceutically acceptable salt thereof for use in the treatment of chronic rhinosinusitis |
| WO2025120626A2 (en) | 2025-04-14 | 2025-06-12 | Mitocholine Ltd | Synthetic method |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR6346669D0 (pt) * | 1962-02-12 | 1973-06-14 | Squibb & Sons Inc | Processo de preparacao de uma composicao farmaceutica estavel de sais de esteres de colina |
| JPS61171417A (ja) * | 1985-01-23 | 1986-08-02 | Wakunaga Seiyaku Kk | 抗糖尿病剤 |
| US6294520B1 (en) * | 1989-03-27 | 2001-09-25 | Albert T. Naito | Material for passage through the blood-brain barrier |
| JPH03169498A (ja) * | 1989-11-28 | 1991-07-23 | Yotsukaichi Gosei Kk | 水溶性はんだフラックス |
| JPH0586319A (ja) * | 1991-09-27 | 1993-04-06 | Pentel Kk | 水性インキ組成物 |
| US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
| WO2000051594A1 (en) * | 1999-03-01 | 2000-09-08 | Verteletsky, Pavel Vasilievich | Use of succinic acid or salts thereof and method of treating insulin resistance |
| AU4937699A (en) * | 1999-04-05 | 2000-10-23 | Olga Evgenievna Kolesova | Use of succinic acid or salts thereof for the treatment of diabetes mellitus andwound healing |
-
2000
- 2000-04-10 KR KR1020027013553A patent/KR20020089444A/ko not_active Ceased
- 2000-04-10 WO PCT/RU2000/000122 patent/WO2001076583A1/en not_active Application Discontinuation
- 2000-04-10 CN CN00819413A patent/CN1452482A/zh active Pending
- 2000-04-10 AU AU2000263274A patent/AU2000263274A1/en not_active Abandoned
- 2000-04-10 CA CA002404864A patent/CA2404864A1/en not_active Abandoned
- 2000-04-10 BR BR0017206-5A patent/BR0017206A/pt not_active IP Right Cessation
- 2000-04-10 EP EP00950127A patent/EP1272171A1/en not_active Withdrawn
- 2000-04-10 JP JP2001574101A patent/JP3944393B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1272171A1 (en) | 2003-01-08 |
| WO2001076583A1 (en) | 2001-10-18 |
| CN1452482A (zh) | 2003-10-29 |
| JP3944393B2 (ja) | 2007-07-11 |
| JP2004506605A (ja) | 2004-03-04 |
| BR0017206A (pt) | 2003-01-14 |
| KR20020089444A (ko) | 2002-11-29 |
| CA2404864A1 (en) | 2001-10-18 |
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