AU1425683A - 1-alkyl-1,2,3,4,5,6-hexahydroazepino(4,5-6)indoles - Google Patents

1-alkyl-1,2,3,4,5,6-hexahydroazepino(4,5-6)indoles

Info

Publication number
AU1425683A
AU1425683A AU14256/83A AU1425683A AU1425683A AU 1425683 A AU1425683 A AU 1425683A AU 14256/83 A AU14256/83 A AU 14256/83A AU 1425683 A AU1425683 A AU 1425683A AU 1425683 A AU1425683 A AU 1425683A
Authority
AU
Australia
Prior art keywords
hexahydroazepino
indoles
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14256/83A
Other languages
English (en)
Inventor
Fulvio Gadient
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU1425683A publication Critical patent/AU1425683A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU14256/83A 1982-05-06 1983-05-05 1-alkyl-1,2,3,4,5,6-hexahydroazepino(4,5-6)indoles Abandoned AU1425683A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH280682 1982-05-06
CH2806/82A CH649553A5 (de) 1982-05-06 1982-05-06 Azepinoindole und verfahren zu deren herstellung.

Publications (1)

Publication Number Publication Date
AU1425683A true AU1425683A (en) 1983-11-10

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14256/83A Abandoned AU1425683A (en) 1982-05-06 1983-05-05 1-alkyl-1,2,3,4,5,6-hexahydroazepino(4,5-6)indoles

Country Status (17)

Country Link
JP (1) JPS58203993A (de)
AU (1) AU1425683A (de)
BE (1) BE896590A (de)
CH (1) CH649553A5 (de)
DE (1) DE3315467A1 (de)
DK (1) DK199883A (de)
ES (1) ES8502440A1 (de)
FI (1) FI831475L (de)
FR (1) FR2526434A1 (de)
GB (1) GB2120662B (de)
HU (1) HU189275B (de)
IL (1) IL68576A0 (de)
IT (1) IT1197644B (de)
NL (1) NL8301552A (de)
PT (1) PT76632B (de)
SE (1) SE8302554L (de)
ZA (1) ZA833266B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193083B (en) * 1984-02-22 1987-08-28 Sandoz Ag Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
AR034264A1 (es) * 2000-09-20 2004-02-18 Upjohn Co Derivados azepino(4,5-b)indol sustituidos y composiciones farmaceuticas
DE60206636T2 (de) 2001-08-08 2006-06-22 Pharmacia & Upjohn Co. Llc, Kalamazoo THERAPEUTISCHE 1H-PYRIDO[4,3-b]INDOLE
CA2636992C (en) * 2006-01-19 2015-10-06 Athersys, Inc. Thiophenyl and pyrrolyl azepines as serotonin 5-ht2c receptor ligands and uses thereof
CN101945872B (zh) 2008-01-11 2014-07-23 阿尔巴尼分子研究公司 作为mch拮抗剂的(1-吖嗪酮)-取代的吡啶并吲哚
EP2448585B1 (de) 2009-07-01 2014-01-01 Albany Molecular Research, Inc. Azinon-substituiertes azepin[b]indol und pyrido-pyrrolo-azepin mch-1 antagonisten, verfahren zur herstellung und verwendung davon
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
US8629158B2 (en) 2009-07-01 2014-01-14 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US8618299B2 (en) 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3070467D1 (en) * 1979-11-02 1985-05-15 Sandoz Ag Azepinoindoles, process for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL68576A0 (en) 1983-09-30
GB2120662A (en) 1983-12-07
IT1197644B (it) 1988-12-06
SE8302554L (sv) 1983-11-07
CH649553A5 (de) 1985-05-31
JPS58203993A (ja) 1983-11-28
FI831475A0 (fi) 1983-04-29
GB8312159D0 (en) 1983-06-08
GB2120662B (en) 1985-09-11
HU189275B (en) 1986-06-30
FI831475L (fi) 1983-11-07
IT8348232A0 (it) 1983-05-06
DK199883D0 (da) 1983-05-04
ES522008A0 (es) 1985-01-01
SE8302554D0 (sv) 1983-05-04
BE896590A (fr) 1983-10-28
PT76632A (en) 1983-06-01
DK199883A (da) 1983-11-07
DE3315467A1 (de) 1983-11-17
FR2526434A1 (fr) 1983-11-10
PT76632B (en) 1986-01-27
ZA833266B (en) 1984-12-24
ES8502440A1 (es) 1985-01-01
NL8301552A (nl) 1983-12-01

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