AU1423701A - Alkaline salts on n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone) -n'-isonicotinoylhydrazide, which can possess antimicrobial and immunothrope activity, the method for producing these salts, their use as immunomodulator and pharmaceutical - Google Patents

Alkaline salts on n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone) -n'-isonicotinoylhydrazide, which can possess antimicrobial and immunothrope activity, the method for producing these salts, their use as immunomodulator and pharmaceutical

Info

Publication number
AU1423701A
AU1423701A AU14237/01A AU1423701A AU1423701A AU 1423701 A AU1423701 A AU 1423701A AU 14237/01 A AU14237/01 A AU 14237/01A AU 1423701 A AU1423701 A AU 1423701A AU 1423701 A AU1423701 A AU 1423701A
Authority
AU
Australia
Prior art keywords
salts
pyrimidinesulfone
isonicotinoylhydrazide
immunothrope
immunomodulator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14237/01A
Other languages
English (en)
Inventor
Tamara Petrovna Filipskikh
Nikolai Mikhailovich Goloschapov
Elena Nikolaevna Goloschapova
Ljubov Elizarovna Kostjuk
Elena Andreevna Michurina
Alexandr Leonidovich Reshetov
Anatoly Anatolievich Zavarzin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU1423701A publication Critical patent/AU1423701A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU14237/01A 1999-11-05 2000-11-03 Alkaline salts on n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone) -n'-isonicotinoylhydrazide, which can possess antimicrobial and immunothrope activity, the method for producing these salts, their use as immunomodulator and pharmaceutical Abandoned AU1423701A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RO99123407 1999-11-05
RU99123407/14A RU2191015C2 (ru) 1999-11-05 1999-11-05 Динатриевая соль n-(6-метил-2,4-диоксо-1,2,3,4-тетрагидро-5h-пиримидинсульфон)-n'- изоникотиноилгидразида, проявляющая антимикробную и иммунотропную активность, и лекарственное средство на ее основе
PCT/RU2000/000438 WO2001032650A2 (en) 1999-11-05 2000-11-03 Alkaline salts of n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone)-n'-isonicotinoylhydrazide, possess for their preparation, and pharmaceutical composition based on these salts

Publications (1)

Publication Number Publication Date
AU1423701A true AU1423701A (en) 2001-05-14

Family

ID=20226671

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14237/01A Abandoned AU1423701A (en) 1999-11-05 2000-11-03 Alkaline salts on n-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone) -n'-isonicotinoylhydrazide, which can possess antimicrobial and immunothrope activity, the method for producing these salts, their use as immunomodulator and pharmaceutical

Country Status (5)

Country Link
AU (1) AU1423701A (ru)
EA (1) EA200200540A1 (ru)
RU (1) RU2191015C2 (ru)
UA (1) UA72286C2 (ru)
WO (1) WO2001032650A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA013052B1 (ru) * 2004-03-26 2010-02-26 Закрытое Акционерное Общество "Новая Линия" Лекарственное средство
JP5362986B2 (ja) * 2004-06-23 2013-12-11 シンタ ファーマスーティカルズ コーポレイション 癌治療のためのビス（チオ‐ヒドラジドアミド）塩
RU2368609C1 (ru) * 2008-01-09 2009-09-27 Лев Давидович Раснецов Серебряная соль n-(6-метил-2,4-диоксо-1,2,3,4-тетрагидро-5h-пиримидинсульфон)-n'-изоникотиноилгидразида, проявляющая иммунотропную, противомикробную, противогрибковую (противомикотическую) активность, и лекарственное средство на ее основе
MD4075C1 (ru) * 2009-12-31 2011-07-31 Анатолий ЭФКАРПИДИС Способ получения высокодисперсного коллоидного серебра

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620445A1 (de) * 1965-04-15 1970-04-16 Schering Ag Verfahren zur Herstellung von substituierten Hydrazonen
GB1206567A (en) * 1969-03-27 1970-09-23 Fargal Pharmasint Lab Biochim Substituted benzal hydrazone, organic and inorganic salts thereof and processes of preparation therefor
RU2141322C1 (ru) * 1997-08-12 1999-11-20 Голощапов Николай Михайлович Иммуномодулятор с антимикобактериальной активностью "изофон", способ его получения и применения
RU2136668C1 (ru) * 1997-10-07 1999-09-10 Голощапов Николай Михайлович N,n'-(сульфонилди-1,4-фенилен)бис(n'',n''- диметилформамидин)1,2,3,4-тетрагидро-6-метил-2,4- диоксо-5-пиримидинсульфонат, стимулирующий клеточный метаболизм и обладающий иммунотропной и антимикобактериальной активностью

Also Published As

Publication number Publication date
WO2001032650A2 (en) 2001-05-10
WO2001032650A3 (en) 2002-05-10
UA72286C2 (en) 2005-02-15
RU2191015C2 (ru) 2002-10-20
EA200200540A1 (ru) 2002-10-31

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase