ATE92632T1 - Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung. - Google Patents

Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung.

Info

Publication number
ATE92632T1
ATE92632T1 AT88309004T AT88309004T ATE92632T1 AT E92632 T1 ATE92632 T1 AT E92632T1 AT 88309004 T AT88309004 T AT 88309004T AT 88309004 T AT88309004 T AT 88309004T AT E92632 T1 ATE92632 T1 AT E92632T1
Authority
AT
Austria
Prior art keywords
bidentate
members
conjugate
specific binding
spacer moiety
Prior art date
Application number
AT88309004T
Other languages
English (en)
Inventor
Paul C Harris
Chan S Oh
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22294106&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE92632(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Application granted granted Critical
Publication of ATE92632T1 publication Critical patent/ATE92632T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT88309004T 1987-09-30 1988-09-29 Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung. ATE92632T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10323787A 1987-09-30 1987-09-30
EP88309004A EP0315317B2 (de) 1987-09-30 1988-09-29 Aus zwei Verzahnungen bestehendes Konjugat und Verfahren zu seiner Verwendung

Publications (1)

Publication Number Publication Date
ATE92632T1 true ATE92632T1 (de) 1993-08-15

Family

ID=22294106

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88309004T ATE92632T1 (de) 1987-09-30 1988-09-29 Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung.

Country Status (6)

Country Link
EP (1) EP0315317B2 (de)
JP (1) JP2670696B2 (de)
AT (1) ATE92632T1 (de)
AU (1) AU621321B2 (de)
DE (1) DE3882904T2 (de)
ES (1) ES2056936T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534620A (en) * 1987-09-30 1996-07-09 Beckman Instruments, Inc. Method of heterogenous purification using a bidentate conjugate
DE4011601A1 (de) * 1990-04-10 1991-10-17 Boehringer Mannheim Gmbh Hapten-biotin-konjugate und ihre verwendung
US5371021A (en) * 1992-07-17 1994-12-06 Beckman Instruments, Inc. Initial rate photometric method for immunoassay
US5440023A (en) * 1992-09-18 1995-08-08 Beckman Instruments, Inc. Method for making valproic acid derivatives
DE69331570T2 (de) * 1992-10-21 2002-10-02 Dade Behring Inc., Deerfield Agglutinationstest unter Anwendung eines multivalenten Liganden
EP0629292A1 (de) * 1993-01-06 1994-12-21 Beckman Instruments, Inc. Verfahren zur herstellung eines prekonjugats
US5728589A (en) * 1993-08-24 1998-03-17 Wako Pure Chemical Industries, Ltd. Immunoassay method
US5747352A (en) * 1994-05-23 1998-05-05 Beckman Instruments, Inc. Reagents and methods for the rapid and quantitative assay of pharmacological agents
US5627080A (en) * 1994-07-29 1997-05-06 Beckman Instruments, Inc. Detergent-facilitated immunoassay for the rapid and quantitative assay of pharmacological agents
US6656694B2 (en) 2001-01-11 2003-12-02 Theravance, Inc. Method for identifying a ligand for a biological substrate
GB0303919D0 (en) * 2003-02-20 2003-03-26 Purely Proteins Ltd Methods for investigating the specificity of compounds that interact with receptors
JP4780405B2 (ja) * 2006-08-29 2011-09-28 アイシン精機株式会社 結合親和性を利用する被検物質の測定方法、及び被検物質の測定のための結合親和性解析の制御方法
CN113030463B (zh) * 2021-02-04 2023-08-11 北京邦腾生物科技有限公司 一种检测疫苗中蛋白a等杂质的试纸条及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2029011B (en) * 1978-09-01 1983-02-02 Coulson W Use of a synthetic bifunctional ligand for the immunimetric determination of the concentration ratio of two solutes
ATE78100T1 (de) * 1984-11-27 1992-07-15 Behringwerke Ag Bifunktionelle haptene, verfahren zu ihrer herstellung und ihre verwendung.
US4680338A (en) * 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker

Also Published As

Publication number Publication date
JPH02501410A (ja) 1990-05-17
EP0315317A3 (en) 1989-05-24
AU621321B2 (en) 1992-03-12
EP0315317A2 (de) 1989-05-10
DE3882904D1 (de) 1993-09-09
EP0315317B1 (de) 1993-08-04
WO1989003042A1 (en) 1989-04-06
EP0315317B2 (de) 2000-05-10
DE3882904T2 (de) 1993-11-18
JP2670696B2 (ja) 1997-10-29
AU2603288A (en) 1989-04-18
ES2056936T3 (es) 1994-10-16

Similar Documents

Publication Publication Date Title
ATE92632T1 (de) Aus zwei verzahnungen bestehendes konjugat und verfahren zu seiner verwendung.
DE69214942T2 (de) Verfahren für spezifische bindungsassays unter verwendung eines freisetzbaren liganden
EP0310361A3 (de) Aus drei Verzahnungen bestehendes Konjugat und Verfahren zu seiner Verwendung
ES8705634A1 (es) Un procedimiento para la preparacion de un reactivo de inmunoensayo.
ATE125949T1 (de) Rezeptoren für immunkomplexe, verfahren zur ihrer herstellung und verfahren zur prüfung diese benutzend.
DE69229174D1 (de) Verwendung von haloalkylderivaten von reportermolekülen zur analyse der metabolischen aktivität in zellen
DE59003503D1 (de) Verfahren zum Nachweis spezifisch bindefähiger Substanzen in Körperflüssigkeiten.
ES8101647A1 (es) Un metodo de determinacion de ligandos en muestras de ensayo
DE69606324D1 (de) Verwendung von kernspinresonanz zur auffindung von liganden für bindungsmoleküle
DE69032854D1 (de) Verfahren, reagenzien und testkits zum nachweis von subpopulationen biologischer substanzen
SE8400865L (sv) Platinaforening samt forfarande for dess framstellning
KR910003377A (ko) 신규의 형광성 염료
ATE150871T1 (de) Verfahren zur herstellung von biologisch aktiven reagentien aus succinimid enthaltenden polymeren, analytisches element und verwendungsmethoden
DE59410003D1 (de) Synthetischer Standard für Immunoassays
DE3172795D1 (en) Process for the determination of ligands, test kit for carrying out the process and its application
CA2021658A1 (en) Multiplex immunoassay system
KR920701127A (ko) 단백질에 금속 이온을 부착하기 위한 킬레이트제
DE69115518D1 (de) Verfahren zur Abtrennung und Messung von Spurbestandteilen
ATE127588T1 (de) Geminale diphenyl-derivate und ihre verwendung in immunotests.
DE68918286D1 (de) Verfahren zum testen einer immunologisch aktiven substanz und dafür geeignetes reagenz.
EP0819931A3 (de) Verfahren zur quantitativen und/oder qualitativen Bestimmung von Atomen oder Molekülen
DE59108355D1 (de) Verfahren zur immunologischen Bestimmung von Liganden
WO1992007876A1 (de) Ligand-carrierprotein-konjugat
Teasdale Copper‐induced indefinite aggregation of humic substances: theoretical consequences for copper‐binding behaviour
ATE128361T1 (de) Lektinkomplex, sowie verfahren und sonde zu dessen herstellung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification