ATE91283T1 - Verbindungen mit aktivitaet gegen gewebemalaria und verfahren zu ihrer herstellung. - Google Patents

Verbindungen mit aktivitaet gegen gewebemalaria und verfahren zu ihrer herstellung.

Info

Publication number
ATE91283T1
ATE91283T1 AT89402593T AT89402593T ATE91283T1 AT E91283 T1 ATE91283 T1 AT E91283T1 AT 89402593 T AT89402593 T AT 89402593T AT 89402593 T AT89402593 T AT 89402593T AT E91283 T1 ATE91283 T1 AT E91283T1
Authority
AT
Austria
Prior art keywords
free amine
acid
peptide
amino acid
carboxyl group
Prior art date
Application number
AT89402593T
Other languages
English (en)
Inventor
Philippe Pirson
Jean-Bernard Falmagne
Andre Trouet
Original Assignee
Wallone Region
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallone Region filed Critical Wallone Region
Application granted granted Critical
Publication of ATE91283T1 publication Critical patent/ATE91283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT89402593T 1988-09-23 1989-09-21 Verbindungen mit aktivitaet gegen gewebemalaria und verfahren zu ihrer herstellung. ATE91283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8812441A FR2644462B1 (fr) 1988-09-23 1988-09-23 Nouveaux composes actifs sur les formes tissulaires de la malaria et procede de preparation
EP89402593A EP0362031B1 (de) 1988-09-23 1989-09-21 Verbindungen mit Aktivität gegen Gewebemalaria und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE91283T1 true ATE91283T1 (de) 1993-07-15

Family

ID=9370310

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89402593T ATE91283T1 (de) 1988-09-23 1989-09-21 Verbindungen mit aktivitaet gegen gewebemalaria und verfahren zu ihrer herstellung.

Country Status (7)

Country Link
US (1) US5110935A (de)
EP (1) EP0362031B1 (de)
JP (1) JPH02129170A (de)
AT (1) ATE91283T1 (de)
DE (1) DE68907458T2 (de)
ES (1) ES2058576T3 (de)
FR (1) FR2644462B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510356A (en) * 1991-10-03 1996-04-23 University Of Nebraska Board Of Regents Bisquinolines and processes for their production and use to treat malaria
CA2250501C (en) * 1996-03-29 2007-11-13 The University Of Mississippi 8-aminoquinolines
PT1196414E (pt) * 1999-06-25 2003-12-31 Vertex Pharma Pro-farmacos de inibidores carbamato de impdh
BR0318214A (pt) * 2003-03-27 2006-03-21 Council Scient Ind Res análogos de 8-aminoquinolina substituìda no anel, composição anti-malárica, processo para a preparação de análogos de 8-aminoquinolina substituìda no anel, e, uso de análogos de 8-aminoquinolina substituìda no anel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3167679D1 (en) * 1980-03-31 1985-01-24 Inst Int Pathologie Cellulaire Pharmaceutical forms, their preparation and compositions containing the same
FR2546163B1 (fr) * 1983-05-16 1987-10-09 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
FR2612778B1 (fr) * 1987-03-24 1991-10-18 Ire Cell Targ Sa Nouveaux derives d'aminoquinoleine antimalarique, procede de preparation et composition pharmaceutique en contenant
FR2618674B1 (fr) * 1987-07-30 1990-06-15 Ire Celltarg Sa Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation

Also Published As

Publication number Publication date
ES2058576T3 (es) 1994-11-01
FR2644462B1 (fr) 1993-07-09
EP0362031B1 (de) 1993-07-07
US5110935A (en) 1992-05-05
DE68907458T2 (de) 1993-12-16
DE68907458D1 (de) 1993-08-12
JPH02129170A (ja) 1990-05-17
FR2644462A1 (fr) 1990-09-21
EP0362031A1 (de) 1990-04-04

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