ATE8912T1 - Stabilisierte enzymatische loesungen und verfahren zum bestimmen von gesamtcholesterin im menschlichen serum. - Google Patents
Stabilisierte enzymatische loesungen und verfahren zum bestimmen von gesamtcholesterin im menschlichen serum.Info
- Publication number
- ATE8912T1 ATE8912T1 AT81104899T AT81104899T ATE8912T1 AT E8912 T1 ATE8912 T1 AT E8912T1 AT 81104899 T AT81104899 T AT 81104899T AT 81104899 T AT81104899 T AT 81104899T AT E8912 T1 ATE8912 T1 AT E8912T1
- Authority
- AT
- Austria
- Prior art keywords
- cholesterol
- reagent
- solution
- prepared
- total cholesterol
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 6
- 235000012000 cholesterol Nutrition 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 8
- 108010055297 Sterol Esterase Proteins 0.000 abstract 4
- 102000000019 Sterol Esterase Human genes 0.000 abstract 4
- 239000000243 solution Substances 0.000 abstract 4
- 150000002894 organic compounds Chemical class 0.000 abstract 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 abstract 3
- 108010089254 Cholesterol oxidase Proteins 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 2
- 239000007853 buffer solution Substances 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- BHQCQFFYRZLCQQ-UHFFFAOYSA-N (3alpha,5alpha,7alpha,12alpha)-3,7,12-trihydroxy-cholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 BHQCQFFYRZLCQQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000008620 Cholesterol Assay Methods 0.000 abstract 1
- 239000004380 Cholic acid Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 abstract 1
- 229960002471 cholic acid Drugs 0.000 abstract 1
- 235000019416 cholic acid Nutrition 0.000 abstract 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 abstract 1
- 230000036284 oxygen consumption Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16820480A | 1980-07-10 | 1980-07-10 | |
| EP81104899A EP0044432B1 (de) | 1980-07-10 | 1981-06-24 | Stabilisierte enzymatische Lösungen und Verfahren zum Bestimmen von Gesamtcholesterin im menschlichen Serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE8912T1 true ATE8912T1 (de) | 1984-08-15 |
Family
ID=22610542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81104899T ATE8912T1 (de) | 1980-07-10 | 1981-06-24 | Stabilisierte enzymatische loesungen und verfahren zum bestimmen von gesamtcholesterin im menschlichen serum. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0044432B1 (de) |
| JP (1) | JPS5779885A (de) |
| AT (1) | ATE8912T1 (de) |
| CA (1) | CA1198040A (de) |
| DE (1) | DE3165392D1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1177513B (it) * | 1984-01-27 | 1987-08-26 | Menarini Sas | Reattivo liquido pronto per l'uso per la determinazione del contenuto di glucosio nel sangue |
| GB2154735B (en) * | 1984-01-27 | 1987-07-15 | Menarini Sas | Reagent for determining blood glucose content |
| EP0218083A1 (de) * | 1985-09-03 | 1987-04-15 | Abbott Laboratories | Stabilisiertes Reagenz für Cholesterin und Verfahren zur Bestimmung des Gesamtcholesterins mittels dieses Reagenzes |
| DE3636851A1 (de) * | 1986-10-29 | 1988-05-11 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur spezifischen bestimmung des cholesterins der hdl-fraktion |
| DE3726634A1 (de) * | 1987-08-11 | 1989-02-23 | Biotest Ag | Stabilisiertes peroxidasepraeparat |
| JP3679805B2 (ja) * | 1992-06-10 | 2005-08-03 | 協和醗酵工業株式会社 | コレステロール低減化物質の製造法 |
| EP3722418A1 (de) * | 2019-04-08 | 2020-10-14 | AB Enzymes Oy | Lösungsstabile enzymzusammensetzung |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3573171A (en) * | 1968-09-06 | 1971-03-30 | Smith Kline French Lab | Laboratory reagent for assay of lactic acid |
| GB1385319A (en) * | 1971-09-22 | 1975-02-26 | Nat Res Dev | Enzyme preparations |
| DE2264847C2 (de) * | 1972-05-17 | 1978-11-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Reagenz zur Bestimmung von Cholesterin |
| JPS49132289A (de) * | 1973-04-24 | 1974-12-18 | ||
| GB1479994A (en) * | 1974-03-04 | 1977-07-13 | Abbott Lab | Single reagent for the enzymatic determination of cholesterol and method therefor |
| JPS50157588A (de) * | 1974-06-17 | 1975-12-19 | ||
| US4116773A (en) * | 1976-07-01 | 1978-09-26 | Beckman Instruments, Inc. | Enzymatic reagent and method for increasing the sensitivity of enzymatic substrate analyses using oxygen rate analyzers |
| DE2653537C3 (de) * | 1976-11-25 | 1979-08-23 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren und Mittel zur Bestimmung von Hydroperoxiden |
| US4121905A (en) * | 1977-08-22 | 1978-10-24 | Jonas Maurukas | Process for preparing biological compositions for use as reference controls in diagnostic analyses |
| ATE5539T1 (de) * | 1979-08-23 | 1983-12-15 | Ivan Endre Modrovich | Verfahren zur stabilisierung einer enzymatischen loesung zur verwendung bei der bestimmung des gesamt-cholesterols, stabilisierte loesung und reagenzsatz dafuer. |
-
1981
- 1981-06-24 DE DE8181104899T patent/DE3165392D1/de not_active Expired
- 1981-06-24 EP EP81104899A patent/EP0044432B1/de not_active Expired
- 1981-06-24 AT AT81104899T patent/ATE8912T1/de not_active IP Right Cessation
- 1981-06-29 CA CA000380812A patent/CA1198040A/en not_active Expired
- 1981-07-10 JP JP56107173A patent/JPS5779885A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0044432B1 (de) | 1984-08-08 |
| EP0044432A2 (de) | 1982-01-27 |
| JPS5779885A (en) | 1982-05-19 |
| EP0044432A3 (en) | 1982-02-03 |
| DE3165392D1 (en) | 1984-09-13 |
| CA1198040A (en) | 1985-12-17 |
| JPS6335240B2 (de) | 1988-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |