ATE80394T1 - 6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung. - Google Patents

6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung.

Info

Publication number
ATE80394T1
ATE80394T1 AT87309349T AT87309349T ATE80394T1 AT E80394 T1 ATE80394 T1 AT E80394T1 AT 87309349 T AT87309349 T AT 87309349T AT 87309349 T AT87309349 T AT 87309349T AT E80394 T1 ATE80394 T1 AT E80394T1
Authority
AT
Austria
Prior art keywords
pyrridines
piperidylidenes
5hbenzo
cyclohepta
dihydro
Prior art date
Application number
AT87309349T
Other languages
English (en)
Inventor
John J Piwinsky
Michael John Green
Ashit Kumar Ganguly
Jesse Kwok-Keung Wong
Bernard Katchen
Jeffrey Abbott Cramer
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE80394T1 publication Critical patent/ATE80394T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT87309349T 1987-04-28 1987-10-22 6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung. ATE80394T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/043,409 US4804666A (en) 1985-08-14 1987-04-28 Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines

Publications (1)

Publication Number Publication Date
ATE80394T1 true ATE80394T1 (de) 1992-09-15

Family

ID=21927034

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309349T ATE80394T1 (de) 1987-04-28 1987-10-22 6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung.

Country Status (22)

Country Link
US (1) US4804666A (de)
EP (1) EP0288640B1 (de)
JP (1) JPH0780870B2 (de)
KR (1) KR960009426B1 (de)
AR (1) AR246520A1 (de)
AT (1) ATE80394T1 (de)
AU (1) AU612339B2 (de)
CA (1) CA1332172C (de)
DE (1) DE3781679T2 (de)
DK (1) DK540789D0 (de)
ES (1) ES2043665T3 (de)
FI (1) FI96858C (de)
GR (1) GR3006483T3 (de)
HK (1) HK135595A (de)
HU (1) HU202520B (de)
IE (1) IE61740B1 (de)
IL (1) IL84235A (de)
MX (1) MX9203282A (de)
NZ (1) NZ222253A (de)
PH (1) PH26157A (de)
PT (1) PT85975B (de)
WO (1) WO1988008423A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use
KR950004004B1 (ko) * 1988-04-28 1995-04-22 쉐링코포레이션 신규한 벤조피리도 피페리딘, 피페리딜리덴 및 피페라진 화합물, 조성물, 제조방법 및 이용방법
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
US7214683B1 (en) 1994-12-30 2007-05-08 Sepracor Inc. Compositions of descarboethoxyloratadine
US7211582B1 (en) 1994-12-30 2007-05-01 Sepracor Inc. Methods for treating urticaria using descarboethoxyloratadine
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
CH688412A5 (de) * 1997-03-11 1997-09-15 Cilag Ag Verfahren zur Herstellung von 1,4-disubstituierten Piperidinverbindungen.
ATE274498T1 (de) * 1998-07-24 2004-09-15 Russinsky Ltd Verfahren zur herstellung von benzocycloheptapyridin-11-one
US6100274A (en) * 1999-07-07 2000-08-08 Schering Corporation 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
US6114346A (en) * 1999-10-22 2000-09-05 Schering Corporation Treating sleep disorders using desloratadine
SK287684B6 (sk) * 1999-12-20 2011-06-06 Schering Corporation Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním
AU2276801A (en) 1999-12-20 2001-07-03 Schering Corporation Extended release oral dosage composition
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
AU2001296908A1 (en) * 2000-09-29 2002-04-08 Geneva Pharmaceuticals, Inc. Proton pump inhibitor formulation
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
CN102993172B (zh) * 2012-12-19 2014-04-02 天津大学 具有抗组胺活性的三环类化合物、制备方法及用途
US10532737B2 (en) 2017-05-17 2020-01-14 Ford Global Technologies, Llc Cooperative park assist
CN109897027B (zh) * 2019-04-28 2021-11-02 梯尔希（南京）药物研发有限公司 一种3-羟基地氯雷他定代谢物的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (de) * 1963-04-24
DE1470314B2 (de) * 1963-04-24 1974-07-11 Scherico Ltd., Luzern (Schweiz) 5-Substituierte 4-Azadibenzocyloheptene und Verfahren zu ihrer Herstellung
US3717647A (en) 1971-04-09 1973-02-20 Schering Corp Alpha-nicotinoyl phenylacetonitriles
GB1570500A (en) * 1976-01-02 1980-07-02 Sandoz Ltd Anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4h-benzo(4,5) cyclohepta (1,2-b)thiophen-10(9h)-one oxime
US4355036A (en) * 1980-06-19 1982-10-19 Schering Corporation Tricyclic-substituted piperidine antihistamines
US4282233B1 (en) 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
WO1985003707A1 (en) * 1984-02-15 1985-08-29 Schering Corporation 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO AD5,6 BDCYCLOHEPTA AD1,2-b BDPYRIDINE AND ITS SALTS, PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
DE3677842D1 (de) * 1985-05-13 1991-04-11 Schering Corp Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln.
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use

Also Published As

Publication number Publication date
KR960009426B1 (en) 1996-07-19
AR246520A1 (es) 1994-08-31
FI96858B (fi) 1996-05-31
FI96858C (fi) 1996-09-10
EP0288640A1 (de) 1988-11-02
GR3006483T3 (de) 1993-06-21
IL84235A (en) 1994-10-21
DE3781679T2 (de) 1993-01-28
EP0288640B1 (de) 1992-09-09
IE872839L (en) 1988-10-28
JPH02503909A (ja) 1990-11-15
JPH0780870B2 (ja) 1995-08-30
US4804666A (en) 1989-02-14
FI895034A0 (fi) 1989-10-24
HK135595A (en) 1995-09-01
DK540789A (da) 1989-10-30
AU1046588A (en) 1988-12-02
PT85975A (en) 1987-11-01
HU202520B (en) 1991-03-28
DK540789D0 (da) 1989-10-30
IE61740B1 (en) 1994-11-30
NZ222253A (en) 1990-08-28
WO1988008423A1 (en) 1988-11-03
ES2043665T3 (es) 1994-01-01
AU612339B2 (en) 1991-07-11
DE3781679D1 (de) 1992-10-15
CA1332172C (en) 1994-09-27
MX9203282A (es) 1992-07-01
PT85975B (pt) 1992-07-31
IL84235A0 (en) 1988-03-31
KR890700583A (ko) 1989-04-25
PH26157A (en) 1992-03-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee