ATE80394T1 - 6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung. - Google Patents
6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung.Info
- Publication number
- ATE80394T1 ATE80394T1 AT87309349T AT87309349T ATE80394T1 AT E80394 T1 ATE80394 T1 AT E80394T1 AT 87309349 T AT87309349 T AT 87309349T AT 87309349 T AT87309349 T AT 87309349T AT E80394 T1 ATE80394 T1 AT E80394T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrridines
- piperidylidenes
- 5hbenzo
- cyclohepta
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/043,409 US4804666A (en) | 1985-08-14 | 1987-04-28 | Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE80394T1 true ATE80394T1 (de) | 1992-09-15 |
Family
ID=21927034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87309349T ATE80394T1 (de) | 1987-04-28 | 1987-10-22 | 6,11-dihydro-11-(4-piperidyliden)-5hbenzo(5,6>cyclohepta(1,2-b>-pyrridine und zusammensetzungen sowie verfahren zur verwendung. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4804666A (de) |
| EP (1) | EP0288640B1 (de) |
| JP (1) | JPH0780870B2 (de) |
| KR (1) | KR960009426B1 (de) |
| AR (1) | AR246520A1 (de) |
| AT (1) | ATE80394T1 (de) |
| AU (1) | AU612339B2 (de) |
| CA (1) | CA1332172C (de) |
| DE (1) | DE3781679T2 (de) |
| DK (1) | DK540789D0 (de) |
| ES (1) | ES2043665T3 (de) |
| FI (1) | FI96858C (de) |
| GR (1) | GR3006483T3 (de) |
| HK (1) | HK135595A (de) |
| HU (1) | HU202520B (de) |
| IE (1) | IE61740B1 (de) |
| IL (1) | IL84235A (de) |
| MX (1) | MX9203282A (de) |
| NZ (1) | NZ222253A (de) |
| PH (1) | PH26157A (de) |
| PT (1) | PT85975B (de) |
| WO (1) | WO1988008423A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| DE68916699T2 (de) * | 1988-04-28 | 1994-12-01 | Schering Corp | Benzopyridopiperidin, -piperidyliden und -piperazin-Verbindungen, Zusammensetzungen, Methoden zur Herstellung und Verwendung. |
| US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
| US7211582B1 (en) | 1994-12-30 | 2007-05-01 | Sepracor Inc. | Methods for treating urticaria using descarboethoxyloratadine |
| US7214683B1 (en) | 1994-12-30 | 2007-05-08 | Sepracor Inc. | Compositions of descarboethoxyloratadine |
| US5900421A (en) * | 1997-02-11 | 1999-05-04 | Sepracor Inc. | Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine |
| CH688412A5 (de) * | 1997-03-11 | 1997-09-15 | Cilag Ag | Verfahren zur Herstellung von 1,4-disubstituierten Piperidinverbindungen. |
| ATE274498T1 (de) * | 1998-07-24 | 2004-09-15 | Russinsky Ltd | Verfahren zur herstellung von benzocycloheptapyridin-11-one |
| US6100274A (en) * | 1999-07-07 | 2000-08-08 | Schering Corporation | 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions |
| US6114346A (en) * | 1999-10-22 | 2000-09-05 | Schering Corporation | Treating sleep disorders using desloratadine |
| AU2276801A (en) | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
| WO2001045668A2 (en) * | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| WO2002026210A2 (en) * | 2000-09-29 | 2002-04-04 | Geneva Pharmaceuticals Inc. | Proton pump inhibitor formulation |
| US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
| CN102993172B (zh) * | 2012-12-19 | 2014-04-02 | 天津大学 | 具有抗组胺活性的三环类化合物、制备方法及用途 |
| US10532737B2 (en) | 2017-05-17 | 2020-01-14 | Ford Global Technologies, Llc | Cooperative park assist |
| CN109897027B (zh) * | 2019-04-28 | 2021-11-02 | 梯尔希（南京）药物研发有限公司 | 一种3-羟基地氯雷他定代谢物的合成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL132137C (de) * | 1963-04-24 | |||
| DE1470314B2 (de) * | 1963-04-24 | 1974-07-11 | Scherico Ltd., Luzern (Schweiz) | 5-Substituierte 4-Azadibenzocyloheptene und Verfahren zu ihrer Herstellung |
| US3717647A (en) | 1971-04-09 | 1973-02-20 | Schering Corp | Alpha-nicotinoyl phenylacetonitriles |
| GB1570500A (en) * | 1976-01-02 | 1980-07-02 | Sandoz Ltd | Anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4h-benzo(4,5) cyclohepta (1,2-b)thiophen-10(9h)-one oxime |
| US4355036A (en) * | 1980-06-19 | 1982-10-19 | Schering Corporation | Tricyclic-substituted piperidine antihistamines |
| US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| JPS61501205A (ja) * | 1984-02-15 | 1986-06-19 | シェリング・コ−ポレ−ション | ８↓−クロル↓−６，１１↓−ジヒドロ↓−１１↓−（４↓−ピペリジリデン）↓−５Ｈ↓−ベンゾ〔５，６〕シクロヘプタ〔１，２−ｂ〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物 |
| EP0208855B1 (de) * | 1985-05-13 | 1991-03-06 | Schering Corporation | Verfahren zur Herstellung von Piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren Azoderivate, so hergestellte Verbindungen und ihre Anwendung zur Vorbereitung von Heilmitteln |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
-
1987
- 1987-04-28 US US07/043,409 patent/US4804666A/en not_active Expired - Lifetime
- 1987-10-21 IL IL8423587A patent/IL84235A/en not_active IP Right Cessation
- 1987-10-21 NZ NZ222253A patent/NZ222253A/xx unknown
- 1987-10-21 AR AR87309067A patent/AR246520A1/es active
- 1987-10-22 AT AT87309349T patent/ATE80394T1/de not_active IP Right Cessation
- 1987-10-22 PH PH35970A patent/PH26157A/en unknown
- 1987-10-22 JP JP63500439A patent/JPH0780870B2/ja not_active Expired - Fee Related
- 1987-10-22 CA CA000549987A patent/CA1332172C/en not_active Expired - Fee Related
- 1987-10-22 WO PCT/US1987/002689 patent/WO1988008423A1/en active IP Right Grant
- 1987-10-22 ES ES87309349T patent/ES2043665T3/es not_active Expired - Lifetime
- 1987-10-22 EP EP87309349A patent/EP0288640B1/de not_active Expired - Lifetime
- 1987-10-22 DE DE8787309349T patent/DE3781679T2/de not_active Expired - Fee Related
- 1987-10-22 AU AU10465/88A patent/AU612339B2/en not_active Ceased
- 1987-10-22 PT PT85975A patent/PT85975B/pt not_active IP Right Cessation
- 1987-10-22 HU HU88308A patent/HU202520B/hu not_active IP Right Cessation
- 1987-10-22 IE IE283987A patent/IE61740B1/en not_active IP Right Cessation
-
1988
- 1988-12-28 KR KR88701743A patent/KR960009426B1/ko not_active IP Right Cessation
-
1989
- 1989-10-24 FI FI895034A patent/FI96858C/fi not_active IP Right Cessation
- 1989-10-30 DK DK540789A patent/DK540789D0/da not_active Application Discontinuation
-
1992
- 1992-06-24 MX MX9203282A patent/MX9203282A/es unknown
- 1992-12-09 GR GR920402839T patent/GR3006483T3/el unknown
-
1995
- 1995-08-24 HK HK135595A patent/HK135595A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AR246520A1 (es) | 1994-08-31 |
| IE61740B1 (en) | 1994-11-30 |
| CA1332172C (en) | 1994-09-27 |
| HK135595A (en) | 1995-09-01 |
| KR890700583A (ko) | 1989-04-25 |
| DE3781679T2 (de) | 1993-01-28 |
| US4804666A (en) | 1989-02-14 |
| IL84235A (en) | 1994-10-21 |
| NZ222253A (en) | 1990-08-28 |
| FI96858B (fi) | 1996-05-31 |
| JPH02503909A (ja) | 1990-11-15 |
| DE3781679D1 (de) | 1992-10-15 |
| KR960009426B1 (en) | 1996-07-19 |
| DK540789A (da) | 1989-10-30 |
| FI895034A0 (fi) | 1989-10-24 |
| PH26157A (en) | 1992-03-18 |
| EP0288640B1 (de) | 1992-09-09 |
| MX9203282A (es) | 1992-07-01 |
| WO1988008423A1 (en) | 1988-11-03 |
| ES2043665T3 (es) | 1994-01-01 |
| FI96858C (fi) | 1996-09-10 |
| EP0288640A1 (de) | 1988-11-02 |
| PT85975A (en) | 1987-11-01 |
| JPH0780870B2 (ja) | 1995-08-30 |
| AU1046588A (en) | 1988-12-02 |
| HU202520B (en) | 1991-03-28 |
| PT85975B (pt) | 1992-07-31 |
| AU612339B2 (en) | 1991-07-11 |
| IL84235A0 (en) | 1988-03-31 |
| GR3006483T3 (de) | 1993-06-21 |
| IE872839L (en) | 1988-10-28 |
| DK540789D0 (da) | 1989-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |