ATE79745T1 - System zur elektrochemisch kontrollierten arzneiabgabe. - Google Patents

System zur elektrochemisch kontrollierten arzneiabgabe.

Info

Publication number
ATE79745T1
ATE79745T1 AT85850366T AT85850366T ATE79745T1 AT E79745 T1 ATE79745 T1 AT E79745T1 AT 85850366 T AT85850366 T AT 85850366T AT 85850366 T AT85850366 T AT 85850366T AT E79745 T1 ATE79745 T1 AT E79745T1
Authority
AT
Austria
Prior art keywords
drug delivery
controlled drug
chemical
electrochemically controlled
medium
Prior art date
Application number
AT85850366T
Other languages
English (en)
Inventor
Larry L Miller
Baruch Zinger
Ronald L Blankespoor
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of ATE79745T1 publication Critical patent/ATE79745T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/559—Redox delivery systems, e.g. dihydropyridine pyridinium salt redox systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/07—Microporous membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT85850366T 1984-11-19 1985-11-15 System zur elektrochemisch kontrollierten arzneiabgabe. ATE79745T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/673,522 US4585652A (en) 1984-11-19 1984-11-19 Electrochemical controlled release drug delivery system
EP85850366A EP0182765B1 (de) 1984-11-19 1985-11-15 System zur elektrochemisch kontrollierten Arzneiabgabe

Publications (1)

Publication Number Publication Date
ATE79745T1 true ATE79745T1 (de) 1992-09-15

Family

ID=24702999

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85850366T ATE79745T1 (de) 1984-11-19 1985-11-15 System zur elektrochemisch kontrollierten arzneiabgabe.

Country Status (6)

Country Link
US (1) US4585652A (de)
EP (1) EP0182765B1 (de)
JP (1) JPS61196967A (de)
AT (1) ATE79745T1 (de)
CA (1) CA1266887A (de)
DE (1) DE3586560T2 (de)

Families Citing this family (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280155B1 (de) * 1987-02-25 1992-05-20 Hoechst Aktiengesellschaft Mikroenkapsulierung von biologisch aktivem Material
JP2907342B2 (ja) * 1988-01-29 1999-06-21 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア イオン滲透非侵襲的サンプリングまたは送出装置
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
CA1322169C (en) * 1988-04-22 1993-09-14 Hiroshi Yamazaki Ionic dressing of topical administration of drugs to wounds and burns
US5057072A (en) * 1988-10-28 1991-10-15 Medtronic, Inc. Iontophoresis electrode
CA2001444C (en) * 1988-10-28 2000-07-25 Darrel F. Untereker Iontophoresis electrode
IT1229203B (it) * 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
DE69115471T2 (de) * 1990-03-30 1996-05-02 Alza Corp., Palo Alto, Calif. Gerät zur iontophoretischen verabreichung von medikamenten
US5098417A (en) * 1990-04-12 1992-03-24 Ricoh Kyosan, Inc. Cellulosic wound dressing with an active agent ionically absorbed thereon
US5431625A (en) * 1991-02-01 1995-07-11 Empi, Inc. Iontophoresis electronic device having a ramped output current
US5208154A (en) * 1991-04-08 1993-05-04 The United States Of America As Represented By The Department Of Energy Reversibly immobilized biological materials in monolayer films on electrodes
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device
WO1993005680A1 (en) * 1991-09-13 1993-04-01 Gillette Canada Inc. Polymeric particles for dental applications
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5272217A (en) * 1992-03-12 1993-12-21 Regents Of The University Of Minnesota Anisotropic polymers
US5429822A (en) * 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
US5423956A (en) * 1993-07-01 1995-06-13 Regents Of The University Of Minnesota Electrochemical process for the production of conducting polymer fibers
US5536263A (en) * 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
AU2286995A (en) * 1994-04-08 1995-10-30 Alza Corporation Electrotransport system with ion exchange competitive ion capture
US5871460A (en) * 1994-04-08 1999-02-16 Alza Corporation Electrotransport system with ion exchange material providing enhanced drug delivery
WO1996004340A1 (en) * 1994-08-04 1996-02-15 Gordon George Wallace Conducting electroactive biomaterials
US5551953A (en) * 1994-10-31 1996-09-03 Alza Corporation Electrotransport system with remote telemetry link
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
US5635209A (en) * 1995-10-31 1997-06-03 Vintage Pharmaceuticals, Inc. Stabilized composition of levothyroxine sodium medication and method for its production
US5605616A (en) * 1995-11-06 1997-02-25 Versicor, Inc. Reversible charge-based sequestration on solid support
EP0942716B1 (de) 1996-01-30 2005-05-11 Novagent Oy Mittel zur transdermalen verabreichung von arzneistoffen
FI962461A7 (fi) * 1996-06-13 1997-12-14 Novagent Oy Menetelmä ja farmaseuttinen kompositio ihon läpi tehtävään lääkkeen antoon
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
GB9702277D0 (en) * 1997-02-04 1997-03-26 Innes John Centre Modified electrodes and their use
US6295474B1 (en) 1998-03-13 2001-09-25 Intermedics Inc. Defibrillator housing with conductive polymer coating
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7658727B1 (en) 1998-04-20 2010-02-09 Medtronic, Inc Implantable medical device with enhanced biocompatibility and biostability
AU766913B2 (en) 1998-11-02 2003-10-23 Alza Corporation Electrotransport device including a compatible antimicrobial agent
EP1154691A4 (de) * 1999-01-05 2004-07-07 Massachusetts Eye & Ear Infirm Gezielte transsklerale gesteuerte wirkstoffabgabe an die retina und choroidae
DE60031248T2 (de) * 1999-02-18 2007-05-24 Biovalve Technologies, Inc., North Grafton Elektroaktive pore
SE9902474D0 (sv) * 1999-06-30 1999-06-30 Amersham Pharm Biotech Ab Polymer valves
US6334859B1 (en) * 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
US6969382B2 (en) * 1999-07-26 2005-11-29 Zuli Holdings, Ltd. Method and apparatus for treating bodily tissues with medicinal substance
ATE290364T1 (de) 1999-08-18 2005-03-15 Microchips Inc Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien
WO2001035928A1 (en) 1999-11-17 2001-05-25 Microchips, Inc. Microfabricated devices for the delivery of molecules into a carrier fluid
AU4842100A (en) 1999-12-10 2001-06-18 Teri Buseman Anti pruritic patch
DE60027458T2 (de) 1999-12-10 2007-07-05 Massachusetts Institute Of Technology, Cambridge Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren
US6454759B2 (en) * 2000-02-28 2002-09-24 The Regents Of The University Of California Microfabricated injectable drug delivery system
ES2420279T3 (es) * 2000-03-02 2013-08-23 Microchips, Inc. Dispositivos microfabricados y métodos para almacenamiento y exposición selectiva de productos químicos
WO2001091902A2 (en) 2000-05-30 2001-12-06 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
AU2001283359A1 (en) * 2000-08-14 2002-02-25 Pharmacia Corporation Drug release (delivery system)
WO2002013784A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug delivery system with bilayer electrodes
WO2002013785A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug delivery system with burst electrode
AU2002211629A1 (en) * 2000-10-10 2002-04-22 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
US6773429B2 (en) 2000-10-11 2004-08-10 Microchips, Inc. Microchip reservoir devices and facilitated corrosion of electrodes
US6632175B1 (en) 2000-11-08 2003-10-14 Hewlett-Packard Development Company, L.P. Swallowable data recorder capsule medical device
US6929636B1 (en) * 2000-11-08 2005-08-16 Hewlett-Packard Development Company, L.P. Internal drug dispenser capsule medical device
WO2002063073A1 (en) * 2000-12-23 2002-08-15 Wen Lu Long-lived conjugated polymer electrochemical devices incorporating ionic liquids
CA2432438C (en) 2001-01-09 2011-04-26 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
JP2004525109A (ja) * 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
WO2002081024A1 (en) * 2001-04-04 2002-10-17 Alza Corporation Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
WO2002089767A1 (en) 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
US6973718B2 (en) * 2001-05-30 2005-12-13 Microchips, Inc. Methods for conformal coating and sealing microchip reservoir devices
WO2002099457A1 (en) * 2001-05-31 2002-12-12 Massachusetts Inst Technology Microchip devices with improved reservoir opening
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
CA2451953A1 (en) * 2001-06-28 2003-04-24 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US6949763B2 (en) * 2001-10-11 2005-09-27 Marc Ovadia Semiconductor and non-semiconductor non-diffusion-governed bioelectrodes
US20040043066A1 (en) * 2001-10-29 2004-03-04 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
EP1320267B1 (de) 2001-12-14 2005-11-02 STMicroelectronics S.r.l. Verfahren zur Kompression von im Farbfilteranordnungsformat (CFA) aufgenommenen digitalen Bildern
WO2003092665A2 (en) * 2002-05-02 2003-11-13 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
US7687258B1 (en) * 2002-05-20 2010-03-30 Maki Wusi C Direct electric biological agent detector
JP4436258B2 (ja) * 2002-08-16 2010-03-24 マイクロチップス・インコーポレーテッド 制御された放出デバイスおよび方法
US7534241B2 (en) * 2002-09-23 2009-05-19 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
US20060167435A1 (en) * 2003-02-18 2006-07-27 Adamis Anthony P Transscleral drug delivery device and related methods
US6699282B1 (en) * 2003-03-06 2004-03-02 Gelsus Research And Consulting, Inc. Method and apparatus for delivery of medication
US20050055014A1 (en) * 2003-08-04 2005-03-10 Coppeta Jonathan R. Methods for accelerated release of material from a reservoir device
JP2007512859A (ja) * 2003-11-03 2007-05-24 マイクロチップス・インコーポレーテッド グルコースを感知するための医療デバイス
US7662176B2 (en) * 2004-02-19 2010-02-16 Vomaris Innovations, Inc. Footwear apparatus and methods of manufacture and use
US7457667B2 (en) * 2004-02-19 2008-11-25 Silverleaf Medical Products, Inc. Current producing surface for a wound dressing
WO2005084378A2 (en) * 2004-03-05 2005-09-15 Board Of Regents Of University Of Texas System Material and device properties modification by electrochemical charge injection in the absence of contacting electrolyte for either local spatial or final states
US20050220439A1 (en) * 2004-03-19 2005-10-06 Carton Owen A Interactive multimedia system and method
US9011329B2 (en) * 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8337482B2 (en) * 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US20070244520A1 (en) * 2004-04-19 2007-10-18 Searete Llc Lumen-traveling biological interface device and method of use
US8361013B2 (en) * 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US8092549B2 (en) * 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US7998060B2 (en) * 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8512219B2 (en) 2004-04-19 2013-08-20 The Invention Science Fund I, Llc Bioelectromagnetic interface system
US8024036B2 (en) * 2007-03-19 2011-09-20 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US7850676B2 (en) * 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US8353896B2 (en) * 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US7857767B2 (en) * 2004-04-19 2010-12-28 Invention Science Fund I, Llc Lumen-traveling device
JP2008501037A (ja) * 2004-06-01 2008-01-17 マイクロチップス・インコーポレーテッド 医療移植片への／医療移植片からの薬物または分析物の輸送の測定および輸送の増強のためのデバイスおよび方法
WO2006015299A2 (en) * 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
JP5107041B2 (ja) 2004-09-01 2012-12-26 マイクロチップス・インコーポレーテッド レザバ内容物の制御された放出または曝露のための、マルチキャップレザバデバイス
US8834901B2 (en) 2004-10-14 2014-09-16 Trustees Of Tufts College Electrochemically degradable polymers
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
CA2585664C (en) * 2004-11-05 2014-05-20 The Children's Hospital Of Philadelphia Biodegradable linkers for molecular therapies
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
CA2595457A1 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
BRPI0610603A2 (pt) * 2005-04-22 2010-07-06 Ecpoint Medical Inc aparelho para fornecer tratamento eletrolìtico ao tecido, método para o tratamento de uma porção in vivo de tecido, método para melhorar cosmeticamente uma área de pele não estética usando um tratamento eletrolìtico e método de depilação
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
US20070175768A1 (en) * 2005-06-30 2007-08-02 Applera Corporation Microfluidic systems including porous polymer electrodes
EP1907832A1 (de) * 2005-06-30 2008-04-09 Applera Corporation Poröse verbundelektrode mit leitfähigem polymer
US20090214625A1 (en) * 2005-07-15 2009-08-27 Mizuo Nakayama Drug delivery patch
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
CN101282758A (zh) * 2005-08-08 2008-10-08 Tti优而美株式会社 离子电渗疗装置
US8295922B2 (en) * 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20070048362A1 (en) * 2005-08-29 2007-03-01 Transcutaneous Technologies Inc. General purpose electrolyte solution composition for iontophoresis
US8005526B2 (en) * 2005-08-31 2011-08-23 The Regents Of The University Of Michigan Biologically integrated electrode devices
US9084546B2 (en) 2005-08-31 2015-07-21 The Regents Of The University Of Michigan Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications
US20100030128A1 (en) * 2005-09-06 2010-02-04 Kazuma Mitsuguchi Iontophoresis device
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
CN101252968A (zh) * 2005-09-15 2008-08-27 Tti优而美株式会社 棒式离子电渗疗装置
AU2006289888B2 (en) * 2005-09-16 2010-12-02 Tti Ellebeau, Inc. Catheter type iontophoresis apparatus
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
JPWO2007037324A1 (ja) * 2005-09-28 2009-04-09 Ｔｔｉ・エルビュー株式会社 乾燥型イオントフォレーシス用電極構造体
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
WO2007041115A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
WO2007037475A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
EP1928539A1 (de) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Transdermale funktionalisierte mikronadel-arzneiabgabesysteme, vorrichtungen und verfahren
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
JP2009509676A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 ナノ粒子と接合された活性物質のイオントフォレーシス送達
EP1944057A4 (de) * 2005-09-30 2009-02-18 Tti Ellebeau Inc Iontophorese-gerät zur kontrolle der dosis und zeit der verabreichung eines schlafinduzierenden und analeptischen mittels
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US20080033338A1 (en) * 2005-12-28 2008-02-07 Smith Gregory A Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
WO2007079189A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. System and method for remote based control of an iontophoresis device
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US8036738B2 (en) 2006-03-14 2011-10-11 New Jersey Institute Of Technology Iontophoretic transdermal drug delivery system based on conductive polyaniline membrane
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US20120035437A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Navigation of a lumen traveling device toward a target
US20070275035A1 (en) * 2006-05-24 2007-11-29 Microchips, Inc. Minimally Invasive Medical Implant Devices for Controlled Drug Delivery
US20100016957A1 (en) * 2006-05-26 2010-01-21 Edwin Jager Device and method for controlled delivery of chemical substances
WO2007143796A1 (en) * 2006-06-15 2007-12-21 Seagull Ip Pty Ltd A delivery system and process
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
EP2032091A2 (de) 2006-06-29 2009-03-11 Boston Scientific Limited Medizinprodukte mit selektiver beschichtung
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド，インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US8936794B2 (en) * 2006-08-25 2015-01-20 The Regents Of The University Of Michigan Conducting polymer nanotube actuators for precisely controlled release of medicine and bioactive molecules
WO2008030497A2 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
JP2010503469A (ja) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
WO2008034031A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
EP2210625B8 (de) 2006-09-15 2012-02-29 Boston Scientific Scimed, Inc. Biologisch erodierbare Endoprothese mit biostabilen anorganischen Schichten
JP2010503494A (ja) * 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生分解性内部人工器官およびその製造方法
US8052744B2 (en) 2006-09-15 2011-11-08 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
JP2010503482A (ja) 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 内部人工器官
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US8332028B2 (en) * 2006-11-28 2012-12-11 Polyplus Battery Company Protected lithium electrodes for electro-transport drug delivery
US20080122582A1 (en) * 2006-11-29 2008-05-29 Texas Instruments Incorporated Location Based Portable Device Feature Disabler
BRPI0719353A2 (pt) * 2006-12-01 2014-01-07 Titi Ellebeau Inc Sistemas, dispositivos e métodos para dispositivos de energização e/ou controle, por exemplo, dispositivos de distribuição transdérmicos
EP2125065B1 (de) 2006-12-28 2010-11-17 Boston Scientific Limited Bioerodierbare endoprothesen und herstellungsverfahren dafür
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
MX2009012273A (es) * 2007-05-18 2010-04-09 Tti Ellebeau Inc Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
DE102008025525A1 (de) * 2007-05-29 2008-12-18 Textilforschungsinstitut Thüringen-Vogtland e.V. Verfahren zur Herstellung eines elektrisch leitfähigen Garns, textile Struktur für einen transdermalen Wirkstoffspeicher und Verfahren zur Wirkstoffspeicherung
EP1997952B1 (de) * 2007-05-29 2013-08-07 Textilforschungsinstitut Thüringen-Vogtland e.V. Textile Struktur für einen transdermalen Wirkstoffspeicher
PL2167549T3 (pl) * 2007-06-19 2013-03-29 Rynel Inc Materiały zawierające cząstki polimeru rozpuszczalnego w wodzie oraz sposoby ich wytwarzania i stosowania
US20090005824A1 (en) * 2007-06-29 2009-01-01 Polyplus Battery Company Electrotransport devices, methods and drug electrode assemblies
US20090012446A1 (en) * 2007-07-03 2009-01-08 Xinyan Cui Devices, systems and methods for release of chemical agents
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
US20090069740A1 (en) * 2007-09-07 2009-03-12 Polyplus Battery Company Protected donor electrodes for electro-transport drug delivery
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
JP5474831B2 (ja) * 2008-02-08 2014-04-16 テルモ株式会社 生理活性物質管腔内制御送達用薬剤送達装置およびその作成方法
JP5581311B2 (ja) 2008-04-22 2014-08-27 ボストン サイエンティフィック サイムド，インコーポレイテッド 無機材料のコーティングを有する医療デバイス及びその製造方法
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US20090292325A1 (en) 2008-05-02 2009-11-26 Cederna Paul S Hybrid bioelectrical interface device
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
WO2009155328A2 (en) 2008-06-18 2009-12-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
WO2009155405A1 (en) * 2008-06-20 2009-12-23 Boston Scientific Scimed, Inc. Medical devices employing conductive polymers for delivery of therapeutic agents
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
WO2010022226A2 (en) * 2008-08-22 2010-02-25 Boston Scientific Scimed, Inc. Medical devices having a coating for electromagnetically-controlled release of therapeutic agents
US20100069877A1 (en) * 2008-09-10 2010-03-18 Smith Gregory A Apparatus and method to dispense hpc-based viscous liquids into porous substrates, e.g., continuous web-based process
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
WO2010101901A2 (en) 2009-03-02 2010-09-10 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
EP2440694A4 (de) * 2009-06-09 2012-12-19 Tti Ellebeau Inc Langlebige elektrode von hoher kapazität und herstellungsverfahren dafür
US8744568B2 (en) * 2009-12-22 2014-06-03 Boston Scientific Scimed, Inc. Medical device with electroactive polymer powered by photovoltaic cell
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
WO2012097297A2 (en) 2011-01-14 2012-07-19 The Regents Of The University Of Michigan Regenerative peripheral nerve interface
US9713702B2 (en) 2011-03-14 2017-07-25 The Board Of Trustee Of The Leland Stanford Junior University Methods of electric field induced delivery of compounds, compositions used in delivery, and systems of delivery
EP2900315B1 (de) 2012-09-25 2017-09-06 Sorin CRM SAS Vorrichtung zur elektrochemischen freisetzung einer zusammensetzung auf gesteuerte weise
EP3030286B1 (de) 2013-08-05 2019-10-09 Cam Med LLC Anschmiegbare patch pumpe
US10314725B2 (en) 2014-11-13 2019-06-11 The Regents Of The University Of Michigan Method for amplifying signals from individual nerve fascicles
WO2019068288A1 (de) * 2017-10-04 2019-04-11 Berlimed International Research Gmbh Wirkstoff und wirkstoffmatrix enthaltendes produkt zur transdermalen wirkstoffabgabe sowie dessen herstellung und verwendung sowie die wirkstoffmatrix, ihre herstellung und verwendung
US12458588B2 (en) 2021-05-20 2025-11-04 E Ink Corporation Benefit agent delivery system using electroplating

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
DE2626294C3 (de) * 1976-06-11 1980-01-10 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
EP0045142B1 (de) * 1980-07-24 1985-03-27 The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Adsorption an einem Aktivkohlegewebe
EP0060452B1 (de) * 1981-03-05 1985-10-23 Medtronic, Inc. Iontotherapeutisches Gerät
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead

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JPS61196967A (ja) 1986-09-01
EP0182765A2 (de) 1986-05-28
DE3586560D1 (de) 1992-10-01
EP0182765B1 (de) 1992-08-26
CA1266887A (en) 1990-03-20
US4585652A (en) 1986-04-29
EP0182765A3 (en) 1989-02-01
DE3586560T2 (de) 1993-01-14

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