ATE771T1 - Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren. - Google Patents

Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren.

Info

Publication number
ATE771T1
ATE771T1 AT79104413T AT79104413T ATE771T1 AT E771 T1 ATE771 T1 AT E771T1 AT 79104413 T AT79104413 T AT 79104413T AT 79104413 T AT79104413 T AT 79104413T AT E771 T1 ATE771 T1 AT E771T1
Authority
AT
Austria
Prior art keywords
tocopherol
alpha
production
chem
formula
Prior art date
Application number
AT79104413T
Other languages
English (en)
Inventor
Peter Fitton
Ronald Propper
Original Assignee
F. Hoffmann-La Roche & Co. Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche & Co. Aktiengesellschaft filed Critical F. Hoffmann-La Roche & Co. Aktiengesellschaft
Application granted granted Critical
Publication of ATE771T1 publication Critical patent/ATE771T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT79104413T 1978-12-22 1979-11-09 Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren. ATE771T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/972,573 US4208334A (en) 1978-12-22 1978-12-22 Process for preparation of α-tocopherol
EP79104413A EP0012824B1 (de) 1978-12-22 1979-11-09 Verfahren zur Herstellung von alpha-Tocopherol und Zwischenprodukt für dieses Verfahren

Publications (1)

Publication Number Publication Date
ATE771T1 true ATE771T1 (de) 1982-04-15

Family

ID=25519829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79104413T ATE771T1 (de) 1978-12-22 1979-11-09 Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren.

Country Status (5)

Country Link
US (1) US4208334A (de)
EP (1) EP0012824B1 (de)
JP (1) JPS5587784A (de)
AT (1) ATE771T1 (de)
DE (1) DE2962361D1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639533A (en) * 1982-07-29 1987-01-27 Basf Corporation Alpha tocopherol process
DE3367100D1 (en) * 1982-07-29 1986-11-27 Basf Wyandotte Corp Alpha tocopherol process
US4634781A (en) * 1982-09-30 1987-01-06 Basf Corporation Alpha tocopherol process
FR2578844B1 (fr) * 1985-03-15 1987-04-10 Rhone Poulenc Sante Derives du tocopherol, leur preparation et leur emploi
SU1364235A3 (ru) * 1984-09-20 1987-12-30 Рон-Пуленк Санте (Фирма) Способ получени производных @ -Токоферола или их ацетатов
FR2733977B1 (fr) * 1995-05-10 1997-07-04 Rhone Poulenc Nutrition Animal Procede de preparation de phenols substitues
ES2191078T3 (es) * 1996-01-05 2003-09-01 Hoffmann La Roche Procedimiento de obtencion de d,1-alfa-tocoferol en presencia de un catalizador de acido perfluoroalquilensulfonico.
US5908939A (en) * 1996-11-11 1999-06-01 Roche Vitamins Inc. Method of making D,L-A-tocopherol
US7626046B2 (en) * 2001-10-31 2009-12-01 Dsm Ip Assets B.V. Manufacture of α-tocopherol
CN102285955B (zh) * 2011-09-14 2012-12-05 重庆大学 一种α-生育酚乙酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2411968A (en) * 1938-03-31 1946-12-03 Hoffmann La Roche Process for the preparation of synthetic dl-tocopherols
US2723278A (en) * 1954-01-25 1955-11-08 Hoffmann La Roche Preparation of alpha-tocopherol
CH547278A (de) * 1971-01-11 1974-03-29 Hoffmann La Roche Verfahren zur herstellung von chromanderivaten.

Also Published As

Publication number Publication date
JPS5587784A (en) 1980-07-02
US4208334A (en) 1980-06-17
EP0012824B1 (de) 1982-03-24
EP0012824A1 (de) 1980-07-09
DE2962361D1 (en) 1982-04-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee