ATE771T1 - Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren. - Google Patents
Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren.Info
- Publication number
- ATE771T1 ATE771T1 AT79104413T AT79104413T ATE771T1 AT E771 T1 ATE771 T1 AT E771T1 AT 79104413 T AT79104413 T AT 79104413T AT 79104413 T AT79104413 T AT 79104413T AT E771 T1 ATE771 T1 AT E771T1
- Authority
- AT
- Austria
- Prior art keywords
- tocopherol
- alpha
- production
- chem
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 4
- 229940087168 alpha tocopherol Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229960000984 tocofersolan Drugs 0.000 title abstract 2
- 239000002076 α-tocopherol Substances 0.000 title abstract 2
- 235000004835 α-tocopherol Nutrition 0.000 title abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- QAEDZJGFFMLHHQ-UHFFFAOYSA-N trifluoroacetic anhydride Chemical compound FC(F)(F)C(=O)OC(=O)C(F)(F)F QAEDZJGFFMLHHQ-UHFFFAOYSA-N 0.000 abstract 2
- AUFZRCJENRSRLY-UHFFFAOYSA-N 2,3,5-trimethylhydroquinone Chemical compound CC1=CC(O)=C(C)C(C)=C1O AUFZRCJENRSRLY-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001189 phytyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])C([H])([H])[C@@](C([H])([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@](C([H])([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/972,573 US4208334A (en) | 1978-12-22 | 1978-12-22 | Process for preparation of α-tocopherol |
| EP79104413A EP0012824B1 (de) | 1978-12-22 | 1979-11-09 | Verfahren zur Herstellung von alpha-Tocopherol und Zwischenprodukt für dieses Verfahren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE771T1 true ATE771T1 (de) | 1982-04-15 |
Family
ID=25519829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79104413T ATE771T1 (de) | 1978-12-22 | 1979-11-09 | Verfahren zur herstellung von alpha-tocopherol und zwischenprodukt fuer dieses verfahren. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4208334A (de) |
| EP (1) | EP0012824B1 (de) |
| JP (1) | JPS5587784A (de) |
| AT (1) | ATE771T1 (de) |
| DE (1) | DE2962361D1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0100471B1 (de) * | 1982-07-29 | 1986-10-22 | BASF Corporation | Verfahren zur Herstellung von alpha-Tocopherol |
| US4639533A (en) * | 1982-07-29 | 1987-01-27 | Basf Corporation | Alpha tocopherol process |
| US4634781A (en) * | 1982-09-30 | 1987-01-06 | Basf Corporation | Alpha tocopherol process |
| FR2578844B1 (fr) * | 1985-03-15 | 1987-04-10 | Rhone Poulenc Sante | Derives du tocopherol, leur preparation et leur emploi |
| EP0176435B1 (de) * | 1984-09-20 | 1988-10-12 | Rhone-Poulenc Sante | Tocopherol-Derivate, ihre Herstellung und Verwendung |
| FR2733977B1 (fr) * | 1995-05-10 | 1997-07-04 | Rhone Poulenc Nutrition Animal | Procede de preparation de phenols substitues |
| DE59610172D1 (de) | 1996-01-05 | 2003-04-03 | Hoffmann La Roche | Verfahren zur Herstellung von d,l-alpha-Tocopherol in Gegenwart einer Perfluoralkylensulfonsäure als Katalysator |
| US5908939A (en) * | 1996-11-11 | 1999-06-01 | Roche Vitamins Inc. | Method of making D,L-A-tocopherol |
| JP2005507422A (ja) * | 2001-10-31 | 2005-03-17 | ディーエスエム アイピー アセッツ ビー．ブイ． | α−トコフェロールの製造 |
| CN102285955B (zh) * | 2011-09-14 | 2012-12-05 | 重庆大学 | 一种α-生育酚乙酸酯的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2411968A (en) * | 1938-03-31 | 1946-12-03 | Hoffmann La Roche | Process for the preparation of synthetic dl-tocopherols |
| US2723278A (en) * | 1954-01-25 | 1955-11-08 | Hoffmann La Roche | Preparation of alpha-tocopherol |
| CH547278A (de) * | 1971-01-11 | 1974-03-29 | Hoffmann La Roche | Verfahren zur herstellung von chromanderivaten. |
-
1978
- 1978-12-22 US US05/972,573 patent/US4208334A/en not_active Expired - Lifetime
-
1979
- 1979-11-09 DE DE7979104413T patent/DE2962361D1/de not_active Expired
- 1979-11-09 EP EP79104413A patent/EP0012824B1/de not_active Expired
- 1979-11-09 AT AT79104413T patent/ATE771T1/de not_active IP Right Cessation
- 1979-12-20 JP JP16495479A patent/JPS5587784A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4208334A (en) | 1980-06-17 |
| JPS5587784A (en) | 1980-07-02 |
| EP0012824B1 (de) | 1982-03-24 |
| EP0012824A1 (de) | 1980-07-09 |
| DE2962361D1 (en) | 1982-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |