ATE733T1 - 2'-deoxy-5-fluorouridin-derivate, ein verfahren zu deren herstellung und sie enthaltende antitumor-zusammensetzungen. - Google Patents

2'-deoxy-5-fluorouridin-derivate, ein verfahren zu deren herstellung und sie enthaltende antitumor-zusammensetzungen.

Info

Publication number
ATE733T1
ATE733T1 AT79301782T AT79301782T ATE733T1 AT E733 T1 ATE733 T1 AT E733T1 AT 79301782 T AT79301782 T AT 79301782T AT 79301782 T AT79301782 T AT 79301782T AT E733 T1 ATE733 T1 AT E733T1
Authority
AT
Austria
Prior art keywords
deoxy
fluorouridine
antitumors
preparation
compositions containing
Prior art date
Application number
AT79301782T
Other languages
English (en)
Inventor
Setsuro Fujii
Euechi Sakakibara
Original Assignee
Funai Pharmaceutical Ind., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Funai Pharmaceutical Ind., Ltd. filed Critical Funai Pharmaceutical Ind., Ltd.
Application granted granted Critical
Publication of ATE733T1 publication Critical patent/ATE733T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT79301782T 1978-09-05 1979-08-31 2'-deoxy-5-fluorouridin-derivate, ein verfahren zu deren herstellung und sie enthaltende antitumor-zusammensetzungen. ATE733T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10895578A JPS5535057A (en) 1978-09-05 1978-09-05 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it
EP79301782A EP0009882B1 (de) 1978-09-05 1979-08-31 2'-Deoxy-5-fluorouridin-Derivate, ein Verfahren zu deren Herstellung und sie enthaltende Antitumor-Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE733T1 true ATE733T1 (de) 1982-03-15

Family

ID=14497883

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79301782T ATE733T1 (de) 1978-09-05 1979-08-31 2'-deoxy-5-fluorouridin-derivate, ein verfahren zu deren herstellung und sie enthaltende antitumor-zusammensetzungen.

Country Status (7)

Country Link
US (2) US4599404A (de)
EP (1) EP0009882B1 (de)
JP (1) JPS5535057A (de)
AT (1) ATE733T1 (de)
CA (1) CA1121811A (de)
DE (1) DE2962235D1 (de)
ES (1) ES483854A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924999B2 (ja) * 1978-06-10 1984-06-13 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体の製造法
GB2072164B (en) * 1980-02-15 1983-12-21 Funai Pharmaceutical Ind Ltd 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives
EP0082668A1 (de) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenvinyl)-2'-Deoxyuridinderivate, Verfahren zu ihrer Herstellung, die sie enthaltende pharmazeutische Präparate und ihre Verwendung bei der Bekämpfung von viralen Infektionen
JPS6041922A (ja) * 1984-07-17 1985-03-05 松下電器産業株式会社 飲料製造機
JPS6041924A (ja) * 1984-07-17 1985-03-05 松下電器産業株式会社 飲料製造機
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
DK174238B1 (da) * 1984-10-30 2002-10-07 Otsuka Pharma Co Ltd 5-Fluoruracilderivater, deres fremstilling og lægemidler indeholdende sådanne forbindelser
JPH0678478B2 (ja) * 1986-03-19 1994-10-05 ユニチカ株式会社 熱可塑性樹脂組成物
EP0247381B1 (de) * 1986-04-30 1993-08-04 Otsuka Pharmaceutical Co., Ltd. 5-Fluoro-Uracil-Derivate
AU610913B2 (en) * 1987-07-31 1991-05-30 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US4992534A (en) * 1987-08-12 1991-02-12 Otsuka Pharmaceutical Co., Ltd. 3'-O-,5'-O-derivatives of 2'-deoxy-5-fluorouridine
US4981908A (en) * 1988-02-02 1991-01-01 E. I. Du Pont De Nemours And Company Thermoplastic elastomer blends
AU610344B2 (en) * 1988-02-29 1991-05-16 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
CN113234064B (zh) * 2021-05-27 2022-03-29 西南医科大学附属中医医院 一种替加氟衍生物及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3168513A (en) * 1962-03-02 1965-02-02 Hoffmann La Roche Derivative of 2'-deoxy-5-fluorouridine
US3309359A (en) * 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3975367A (en) * 1971-06-08 1976-08-17 The Upjohn Company Arabinofuranosyl N4 -aminoacyl cytosine containing compounds
DE2614946A1 (de) * 1975-04-08 1976-10-14 Asahi Chemical Ind Neue nucleotidderivate
DE2658672A1 (de) * 1976-12-23 1978-06-29 Robugen Gmbh Neue nucleosid-verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS5611718B2 (de) 1981-03-16
US4490366A (en) 1984-12-25
EP0009882B1 (de) 1982-03-03
EP0009882A1 (de) 1980-04-16
DE2962235D1 (en) 1982-04-01
CA1121811A (en) 1982-04-13
US4599404A (en) 1986-07-08
JPS5535057A (en) 1980-03-11
ES483854A1 (es) 1980-09-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee