ATE72458T1 - Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen. - Google Patents
Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen.Info
- Publication number
- ATE72458T1 ATE72458T1 AT86302219T AT86302219T ATE72458T1 AT E72458 T1 ATE72458 T1 AT E72458T1 AT 86302219 T AT86302219 T AT 86302219T AT 86302219 T AT86302219 T AT 86302219T AT E72458 T1 ATE72458 T1 AT E72458T1
- Authority
- AT
- Austria
- Prior art keywords
- ribosomes
- cell cultures
- mutant
- protein
- producing proteins
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 210000003705 ribosome Anatomy 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003161 proteinsynthetic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/716,781 US4772555A (en) | 1985-03-27 | 1985-03-27 | Dedicated ribosomes and their use |
| EP86302219A EP0196223B1 (de) | 1985-03-27 | 1986-03-26 | Zugeordnete Ribosomen und ihre Verwendung zur Herstellung von Proteinen aus Zellkulturen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE72458T1 true ATE72458T1 (de) | 1992-02-15 |
Family
ID=24879402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86302219T ATE72458T1 (de) | 1985-03-27 | 1986-03-26 | Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4772555A (de) |
| EP (1) | EP0196223B1 (de) |
| JP (1) | JPS61224991A (de) |
| AT (1) | ATE72458T1 (de) |
| DE (1) | DE3683784D1 (de) |
| IE (1) | IE58424B1 (de) |
| IL (1) | IL78270A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232840A (en) * | 1986-03-27 | 1993-08-03 | Monsanto Company | Enhanced protein production in bacteria by employing a novel ribosome binding site |
| US6970182B1 (en) * | 1999-10-20 | 2005-11-29 | National Instruments Corporation | Image acquisition system and method for acquiring variable sized objects |
| FR2810675B1 (fr) * | 2000-06-22 | 2002-09-27 | Pf Medicament | Construction modifiee en aval du codon d'initiation pour la surexpression de proteines recombinantes |
| EP1539944A4 (de) | 2002-07-01 | 2005-12-28 | Univ Wayne State | Verfahren und zusammensetzungen zur identifizierung von gegenüber antibiotikaresistenz unempfindlichen antibiotika |
| EP1899483A4 (de) * | 2005-05-11 | 2009-02-11 | Univ Wayne State | Neue ziele für die identifizierung von gegenüber antibiotikaresistenz unempfindlichen antibiotika |
| US8293517B2 (en) * | 2005-05-11 | 2012-10-23 | Wayne State University | Methods and compositions for the identification of antibiotics that are not susceptible to antibiotic resistance in Pseudomonas aeruginosa |
| US8362203B2 (en) * | 2009-02-10 | 2013-01-29 | Wayne State University | Non-natural peptides as models for the development of antibiotics |
| WO2020194311A1 (en) * | 2019-03-28 | 2020-10-01 | Ramot At Tel-Aviv University Ltd. | Methods for modifying translation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582800A (en) * | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
-
1985
- 1985-03-27 US US06/716,781 patent/US4772555A/en not_active Expired - Lifetime
-
1986
- 1986-03-25 IL IL78270A patent/IL78270A/xx unknown
- 1986-03-26 AT AT86302219T patent/ATE72458T1/de not_active IP Right Cessation
- 1986-03-26 IE IE80086A patent/IE58424B1/en not_active IP Right Cessation
- 1986-03-26 EP EP86302219A patent/EP0196223B1/de not_active Expired
- 1986-03-26 DE DE8686302219T patent/DE3683784D1/de not_active Expired - Lifetime
- 1986-03-27 JP JP61070607A patent/JPS61224991A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL78270A (en) | 1992-06-21 |
| IE860800L (en) | 1986-09-27 |
| IL78270A0 (en) | 1986-07-31 |
| EP0196223B1 (de) | 1992-02-05 |
| EP0196223A2 (de) | 1986-10-01 |
| US4772555A (en) | 1988-09-20 |
| DE3683784D1 (de) | 1992-03-19 |
| JPS61224991A (ja) | 1986-10-06 |
| IE58424B1 (en) | 1993-09-22 |
| EP0196223A3 (en) | 1988-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |