ATE67417T1 - Medizinische einrichtung zur pulsatilen transdermalen verabreichung von biologisch aktiven wirkstoffen. - Google Patents

Medizinische einrichtung zur pulsatilen transdermalen verabreichung von biologisch aktiven wirkstoffen.

Info

Publication number
ATE67417T1
ATE67417T1 AT86308248T AT86308248T ATE67417T1 AT E67417 T1 ATE67417 T1 AT E67417T1 AT 86308248 T AT86308248 T AT 86308248T AT 86308248 T AT86308248 T AT 86308248T AT E67417 T1 ATE67417 T1 AT E67417T1
Authority
AT
Austria
Prior art keywords
drug
flux
medical device
administration
period
Prior art date
Application number
AT86308248T
Other languages
English (en)
Inventor
Robert M Gale
Randall G Berggren
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE67417T1 publication Critical patent/ATE67417T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AT86308248T 1985-10-30 1986-10-23 Medizinische einrichtung zur pulsatilen transdermalen verabreichung von biologisch aktiven wirkstoffen. ATE67417T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/792,941 US4698062A (en) 1985-10-30 1985-10-30 Medical device for pulsatile transdermal delivery of biologically active agents
EP86308248A EP0227252B1 (de) 1985-10-30 1986-10-23 Medizinische Einrichtung zur pulsatilen transdermalen Verabreichung von biologisch aktiven Wirkstoffen

Publications (1)

Publication Number Publication Date
ATE67417T1 true ATE67417T1 (de) 1991-10-15

Family

ID=25158559

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86308248T ATE67417T1 (de) 1985-10-30 1986-10-23 Medizinische einrichtung zur pulsatilen transdermalen verabreichung von biologisch aktiven wirkstoffen.

Country Status (11)

Country Link
US (1) US4698062A (de)
EP (1) EP0227252B1 (de)
JP (1) JPS62129058A (de)
KR (1) KR870003798A (de)
AT (1) ATE67417T1 (de)
AU (1) AU582075B2 (de)
CA (1) CA1275216C (de)
DE (1) DE3681570D1 (de)
ES (1) ES2024423B3 (de)
GR (1) GR3002747T3 (de)
ZA (1) ZA868070B (de)

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DE3908431A1 (de) * 1989-03-15 1990-09-27 Lohmann Therapie Syst Lts Transdermales system mit gestufter wirkstoffabgabe und verwendung fuer die lokale oder systemische wirkstoffverabreichung
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US5091186A (en) * 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
AU647103B2 (en) * 1990-03-30 1994-03-17 Alza Corporation Iontophoretic delivery device
US5207752A (en) * 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
US5352456A (en) * 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
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DE4423850A1 (de) * 1994-07-07 1996-01-11 Labtec Gmbh Transdermales therapeutisches System zur Applikation von Naloxon
US5902603A (en) * 1995-09-14 1999-05-11 Cygnus, Inc. Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US6660295B2 (en) 1997-09-30 2003-12-09 Alza Corporation Transdermal drug delivery device package with improved drug stability
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
EP1037686B1 (de) * 1997-12-11 2005-08-17 Alza Corporation Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP1035889B1 (de) * 1997-12-11 2002-07-31 Alza Corporation Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP1911488A3 (de) 1997-12-11 2008-12-03 Alza Corporation Vorrichtung zur Verstärkung des Flusses transdermaler Mittel
EP1037687B8 (de) 1997-12-11 2008-10-22 Alza Corporation Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
ATE223208T1 (de) 1997-12-22 2002-09-15 Alza Corp Membranen zur steuerung des durchflusses in vorrichtungen mit kontrollierter wirkstoffabgabe
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US6348210B1 (en) 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
AU774594B2 (en) 1998-12-18 2004-07-01 Alza Corporation Transparent transdermal nicotine delivery devices
US20070196490A1 (en) * 1999-01-22 2007-08-23 Powderject Research Limited Method of enhancing needleless transdermal powered drug delivery
JP2002541094A (ja) * 1999-04-01 2002-12-03 アルザ・コーポレーション ポリウレタン薬物貯蔵部を含んでなる経皮薬物送達装置
DK1239916T3 (da) 1999-12-10 2006-04-03 Alza Corp Indretning og fremgangsmåde til at forbedre perforering af hud med mikrofremspring
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
US20070196456A1 (en) * 2005-09-15 2007-08-23 Visible Assets, Inc. Smart patch
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
ATE537826T1 (de) * 2006-05-16 2012-01-15 Knopp Neurosciences Inc Zusammensetzungen aus r(+)- und s(-)-pramipexol sowie verfahren zu ihrer anwendung
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
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KR101522747B1 (ko) * 2007-08-06 2015-05-26 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
EP2334185A4 (de) 2008-08-19 2011-09-21 Knopp Neurosciences Inc Zusammensetzungen und verfahren zur verwendung von (r)-pramipexol
US9387033B2 (en) * 2008-08-28 2016-07-12 Roche Diabetes Care, Inc. Device and method for enhanced subcutaneous insulin absorption
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US9522263B2 (en) 2010-04-28 2016-12-20 Kimberly-Clark Worldwide, Inc. Device for delivery of rheumatoid arthritis medication
CN106390128B (zh) 2011-01-10 2022-07-08 伊沃恩有限公司 β-肾上腺素能反向激动剂用于戒烟的用途
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
PL3542851T3 (pl) 2011-10-27 2022-04-25 Sorrento Therapeutics, Inc. Wszczepialne urządzenia do dostarczania środków biologicznie czynnych
AU2012328037B2 (en) 2011-10-27 2017-11-02 Vivasor, Inc. Transdermal delivery of high viscosity bioactive agents
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US20140114248A1 (en) * 2012-10-24 2014-04-24 Nuance Designs, LLC Power pack for an autoinjector
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Also Published As

Publication number Publication date
ES2024423B3 (es) 1992-03-01
AU582075B2 (en) 1989-03-09
US4698062A (en) 1987-10-06
AU6432086A (en) 1987-05-07
CA1275216C (en) 1990-10-16
DE3681570D1 (de) 1991-10-24
EP0227252A2 (de) 1987-07-01
EP0227252A3 (en) 1989-04-05
ZA868070B (en) 1987-06-24
EP0227252B1 (de) 1991-09-18
JPS62129058A (ja) 1987-06-11
GR3002747T3 (en) 1993-01-25
KR870003798A (ko) 1987-05-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee