ATE65397T1 - Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol. - Google Patents

Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol.

Info

Publication number
ATE65397T1
ATE65397T1 AT88202492T AT88202492T ATE65397T1 AT E65397 T1 ATE65397 T1 AT E65397T1 AT 88202492 T AT88202492 T AT 88202492T AT 88202492 T AT88202492 T AT 88202492T AT E65397 T1 ATE65397 T1 AT E65397T1
Authority
AT
Austria
Prior art keywords
acid
oligomers
butanediol
esters
derivative
Prior art date
Application number
AT88202492T
Other languages
English (en)
Inventor
William Nichels
Oultremont Philippe D
Original Assignee
Solvay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay filed Critical Solvay
Application granted granted Critical
Publication of ATE65397T1 publication Critical patent/ATE65397T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT88202492T 1987-11-19 1988-11-08 Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol. ATE65397T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE8701314A BE1001209A3 (fr) 1987-11-19 1987-11-19 Compositions pharmaceutiques contenant un derive de l'acide 3-hydroxybutanoique choisi parmi les oligomeres de cet acide et les esters de cet acide ou de ces oligomeres avec du 1,3-butanediol.
EP88202492A EP0316993B1 (de) 1987-11-19 1988-11-08 Pharmazeutische Zusammensetzungen mit Gehalt an einem Derivat der 3-Hydroxy-Buttersäure, ausgewählt aus den Oligomeren dieser Säure und den Estern dieser Säure oder dieser Oligomere mit dem 1,3-Butan-diol

Publications (1)

Publication Number Publication Date
ATE65397T1 true ATE65397T1 (de) 1991-08-15

Family

ID=3882973

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88202492T ATE65397T1 (de) 1987-11-19 1988-11-08 Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol.

Country Status (10)

Country Link
US (1) US5112865A (de)
EP (1) EP0316993B1 (de)
JP (1) JPH01160917A (de)
AT (1) ATE65397T1 (de)
BE (1) BE1001209A3 (de)
CA (1) CA1330307C (de)
DE (1) DE3863904D1 (de)
DK (1) DK168269B1 (de)
ES (1) ES2037818T3 (de)
GR (1) GR3002605T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126373A (en) * 1987-11-19 1992-06-30 Henri Brunengraber Composition for parenteral and oral nutrition
AU749638B2 (en) * 1997-03-17 2002-06-27 Btg International Limited Therapeutic compositions
US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
US20090253781A1 (en) * 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
US6164451A (en) * 1998-03-16 2000-12-26 Trish Mcevoy, Ltd. Cosmetics case
DE19830310A1 (de) * 1998-07-07 2000-01-13 Riedel De Haen Gmbh Verfahren zur Abreicherung des Bromidgehaltes aus einer wäßrigen Bromid enthaltenden Lösung unter Verwendung von Wasserstoffperoxid
MXPA01000632A (es) 1998-07-22 2002-05-06 Metabolix Inc Usos nutricionales y terapeuticos de oligomeros 3-hidroxialcanoato.
US20020077269A1 (en) * 2000-10-27 2002-06-20 Whitehouse Robert S. Alkanoic acid ester monomer compositions and methods of making same
US7230144B2 (en) * 2001-12-18 2007-06-12 Metabolix Inc. Methods of making intermediates from polyhydroxyalkanoates
US20060280721A1 (en) 2003-06-03 2006-12-14 The Gov Of Usa Represented By Secretary Of Dpt Of Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives
GB0410266D0 (en) * 2004-05-07 2004-06-09 Ketocytonyx Inc Treatment of apoptosis
EP2240017B1 (de) 2008-01-04 2019-03-13 Oxford University Innovation Limited Ketonkörper und ketonkörperester als blutfettsenkende mittel
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
EP3296284B1 (de) * 2008-08-21 2021-12-01 The Government of the United States of America, as repres. by the Secretary of Health and Human Services, Nat. Inst. of Health Nicht-medizinische verwendung eines hydroxybutyratesters
RU2012133186A (ru) 2010-02-11 2014-03-20 Метаболикс, Инк. Способ получения гамма-бутиролактона
GB201002983D0 (en) 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
WO2014071389A1 (en) 2012-11-05 2014-05-08 Veech Richard L Ketone bodies to protect tissues from damage by ionizing radiation
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
CN105246870A (zh) 2013-03-14 2016-01-13 伊希斯创新有限公司 (r)-3-羟基丁酸(r)-3-羟基丁酯的制备方法
CN109477993B (zh) 2016-06-07 2023-03-28 J大卫格莱斯顿研究机构 β-羟基丁酸酯和丁二醇的中链脂肪酸酯和组合物及其使用方法
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
US11773051B2 (en) 2017-07-21 2023-10-03 Buck Institute For Research On Aging S-enantiomers of beta-hydroxybutyrate and butanediol and methods for using same
US11760963B2 (en) 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
WO2019147503A1 (en) 2018-01-25 2019-08-01 Buck Institute For Research On Aging Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
US12396974B2 (en) 2020-03-27 2025-08-26 KetoneAid Ketone ester as a therapeutic treatment of Covid-19 and related viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2500310C2 (de) * 1975-01-07 1984-01-19 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol-(1,3)-1-mono-(3'-hydroxybutyraten)sowie einige dieser Butandiol-(1,3)-1-mono-(3'-hydroxybutyrate)
DE2500312C2 (de) * 1975-01-07 1984-01-19 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol-(1,3)-3-mono-(3'-hydroxybutyraten)sowie einige dieser Butandiol-(1,3)-3-mono-(3'-hydroxybutyrate)
FR2486072A1 (fr) * 1980-07-03 1982-01-08 Solvay Procede pour la fabrication de l'acide b-hydroxybutyrique et de ses oligocondensats
US4574085A (en) * 1981-05-15 1986-03-04 Baxter Travenol Laboratories, Inc. Method for using dialysis solution containing glycerol
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee
WO1987003808A1 (en) * 1985-12-18 1987-07-02 Veech Richard L Fluid therapy with l-lactate and/or pyruvate anions

Also Published As

Publication number Publication date
EP0316993A1 (de) 1989-05-24
ES2037818T3 (es) 1993-07-01
DK168269B1 (da) 1994-03-07
DE3863904D1 (de) 1991-08-29
DK644388A (da) 1989-07-03
EP0316993B1 (de) 1991-07-24
GR3002605T3 (en) 1993-01-25
US5112865A (en) 1992-05-12
DK644388D0 (da) 1988-11-18
BE1001209A3 (fr) 1989-08-22
CA1330307C (fr) 1994-06-21
JPH01160917A (ja) 1989-06-23

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