ATE65397T1 - Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol. - Google Patents

Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol.

Info

Publication number
ATE65397T1
ATE65397T1 AT88202492T AT88202492T ATE65397T1 AT E65397 T1 ATE65397 T1 AT E65397T1 AT 88202492 T AT88202492 T AT 88202492T AT 88202492 T AT88202492 T AT 88202492T AT E65397 T1 ATE65397 T1 AT E65397T1
Authority
AT
Austria
Prior art keywords
acid
oligomers
butanediol
esters
derivative
Prior art date
Application number
AT88202492T
Other languages
English (en)
Inventor
William Nichels
Oultremont Philippe D
Original Assignee
Solvay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay filed Critical Solvay
Application granted granted Critical
Publication of ATE65397T1 publication Critical patent/ATE65397T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
AT88202492T 1987-11-19 1988-11-08 Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol. ATE65397T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE8701314A BE1001209A3 (fr) 1987-11-19 1987-11-19 Compositions pharmaceutiques contenant un derive de l'acide 3-hydroxybutanoique choisi parmi les oligomeres de cet acide et les esters de cet acide ou de ces oligomeres avec du 1,3-butanediol.
EP88202492A EP0316993B1 (de) 1987-11-19 1988-11-08 Pharmazeutische Zusammensetzungen mit Gehalt an einem Derivat der 3-Hydroxy-Buttersäure, ausgewählt aus den Oligomeren dieser Säure und den Estern dieser Säure oder dieser Oligomere mit dem 1,3-Butan-diol

Publications (1)

Publication Number Publication Date
ATE65397T1 true ATE65397T1 (de) 1991-08-15

Family

ID=3882973

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88202492T ATE65397T1 (de) 1987-11-19 1988-11-08 Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol.

Country Status (10)

Country Link
US (1) US5112865A (de)
EP (1) EP0316993B1 (de)
JP (1) JPH01160917A (de)
AT (1) ATE65397T1 (de)
BE (1) BE1001209A3 (de)
CA (1) CA1330307C (de)
DE (1) DE3863904D1 (de)
DK (1) DK168269B1 (de)
ES (1) ES2037818T3 (de)
GR (1) GR3002605T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126373A (en) * 1987-11-19 1992-06-30 Henri Brunengraber Composition for parenteral and oral nutrition
US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
ES2530753T3 (es) * 1997-03-17 2015-03-05 Btg Int Ltd Composiciones terapéuticas que comprenden cuerpos cetónicos y precursores de los mismos
US20090253781A1 (en) * 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
US6164451A (en) * 1998-03-16 2000-12-26 Trish Mcevoy, Ltd. Cosmetics case
DE19830310A1 (de) * 1998-07-07 2000-01-13 Riedel De Haen Gmbh Verfahren zur Abreicherung des Bromidgehaltes aus einer wäßrigen Bromid enthaltenden Lösung unter Verwendung von Wasserstoffperoxid
CA2338090C (en) 1998-07-22 2009-07-14 Metabolix, Inc. Nutritional and therapeutic compositions of 3-hydroxyacids for increasing blood ketone bodies
US20020077269A1 (en) * 2000-10-27 2002-06-20 Whitehouse Robert S. Alkanoic acid ester monomer compositions and methods of making same
US6933404B2 (en) 2001-12-18 2005-08-23 Metabolix Inc. Methods of making intermediates from polyhydroxyalkanoates
DK1648952T3 (en) 2003-06-03 2018-05-28 The Us Gov As Represented By The Department Of Health And Human Services Dietary supplements and therapeutic compositions comprising (R) -3-hydroxybutyrate derivatives
GB0410266D0 (en) * 2004-05-07 2004-06-09 Ketocytonyx Inc Treatment of apoptosis
DK2240017T3 (da) 2008-01-04 2019-06-17 Univ Oxford Innovation Ltd Ketonlegemer og ketonlegemsestere som blodlipid-sænkende midler
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
ES2655367T3 (es) * 2008-08-21 2018-02-19 Oxford University Innovation Limited Bebida que comprende éster de hidroxibutirato y uso médico de la misma
WO2011100601A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for gamma-butyrolactone production
GB201002983D0 (en) 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
WO2014071389A1 (en) 2012-11-05 2014-05-08 Veech Richard L Ketone bodies to protect tissues from damage by ionizing radiation
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
KR102265842B1 (ko) 2013-03-14 2021-06-15 옥스포드 유니버시티 이노베이션 리미티드 (ｒ)­３­하이드록시부틸 (ｒ)­３­하이드록시부티레이트를 생산하는 방법
EP4585270A3 (de) 2016-06-07 2025-09-24 The J. David Gladstone Institutes Mittelkettige fettsäureester von beta-hydroxybutyrat und butandiol sowie zusammensetzungen und verfahren zur verwendung davon
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
EP3654963A4 (de) * 2017-07-21 2021-04-14 Buck Institute for Research on Aging S-enantiomere von beta-hydroxybutyrat und butandiol sowie verfahren zu deren verwendung
US11760963B2 (en) 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
US12037317B2 (en) 2018-01-25 2024-07-16 Buck Institute For Research On Aging Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
US12396974B2 (en) 2020-03-27 2025-08-26 KetoneAid Ketone ester as a therapeutic treatment of Covid-19 and related viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2500310C2 (de) * 1975-01-07 1984-01-19 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol-(1,3)-1-mono-(3'-hydroxybutyraten)sowie einige dieser Butandiol-(1,3)-1-mono-(3'-hydroxybutyrate)
DE2500312C2 (de) * 1975-01-07 1984-01-19 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol-(1,3)-3-mono-(3'-hydroxybutyraten)sowie einige dieser Butandiol-(1,3)-3-mono-(3'-hydroxybutyrate)
FR2486072A1 (fr) * 1980-07-03 1982-01-08 Solvay Procede pour la fabrication de l'acide b-hydroxybutyrique et de ses oligocondensats
US4574085A (en) * 1981-05-15 1986-03-04 Baxter Travenol Laboratories, Inc. Method for using dialysis solution containing glycerol
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee
AU6776887A (en) * 1985-12-18 1987-07-15 Veech, R.L. Fluid therapy with l-lactate and/or pyruvate anions

Also Published As

Publication number Publication date
EP0316993A1 (de) 1989-05-24
CA1330307C (fr) 1994-06-21
GR3002605T3 (en) 1993-01-25
DE3863904D1 (de) 1991-08-29
DK644388D0 (da) 1988-11-18
JPH01160917A (ja) 1989-06-23
DK644388A (da) 1989-07-03
DK168269B1 (da) 1994-03-07
ES2037818T3 (es) 1993-07-01
EP0316993B1 (de) 1991-07-24
US5112865A (en) 1992-05-12
BE1001209A3 (fr) 1989-08-22

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