ATE63464T1 - Spruehgetrocknetes acetaminophen. - Google Patents

Spruehgetrocknetes acetaminophen.

Info

Publication number
ATE63464T1
ATE63464T1 AT87309255T AT87309255T ATE63464T1 AT E63464 T1 ATE63464 T1 AT E63464T1 AT 87309255 T AT87309255 T AT 87309255T AT 87309255 T AT87309255 T AT 87309255T AT E63464 T1 ATE63464 T1 AT E63464T1
Authority
AT
Austria
Prior art keywords
acetaminophene
spray dried
acetaminophen
neutral
powder
Prior art date
Application number
AT87309255T
Other languages
English (en)
Inventor
Robert George Blank
Dhiraj Shantilal Mody
Gary Robert Agism
Richard John Kenny
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of ATE63464T1 publication Critical patent/ATE63464T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glanulating (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87309255T 1986-10-21 1987-10-20 Spruehgetrocknetes acetaminophen. ATE63464T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/921,557 US4760093A (en) 1986-10-21 1986-10-21 Spray dried acetaminophen
EP87309255A EP0266113B1 (de) 1986-10-21 1987-10-20 Sprühgetrocknetes Acetaminophen

Publications (1)

Publication Number Publication Date
ATE63464T1 true ATE63464T1 (de) 1991-06-15

Family

ID=25445620

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309255T ATE63464T1 (de) 1986-10-21 1987-10-20 Spruehgetrocknetes acetaminophen.

Country Status (11)

Country Link
US (1) US4760093A (de)
EP (1) EP0266113B1 (de)
JP (1) JP2542400B2 (de)
KR (1) KR950013751B1 (de)
AT (1) ATE63464T1 (de)
AU (1) AU594203B2 (de)
CA (1) CA1290251C (de)
DE (1) DE3770116D1 (de)
ES (1) ES2032450T3 (de)
GR (1) GR3002108T3 (de)
IE (1) IE61952B1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286489A (en) * 1985-08-26 1994-02-15 The Procter & Gamble Company Taste masking compositions
US4971791A (en) * 1985-08-26 1990-11-20 The Procter & Gamble Company Taste masking compositions
US4946684A (en) * 1989-06-20 1990-08-07 American Home Products Corporation Fast dissolving dosage forms
US5198228A (en) * 1989-09-14 1993-03-30 Hoechst-Roussel Pharmaceuticals Inc. Direct dry compressible acetaminophen tablet
US5037658A (en) * 1989-09-14 1991-08-06 Hoechst-Roussel Pharmaceuticals, Inc. Direct dry compressible acetaminophen composition
US5130140A (en) * 1989-09-14 1992-07-14 Hoeschst-Roussel Pharmaceuticals Inc. Method of making direct dry compressible acetaminophen composition
GB9305058D0 (en) * 1993-03-12 1993-04-28 Penn Pharm Ltd Pharmaceutical compositions
US5510389A (en) * 1994-03-02 1996-04-23 The Procter & Gamble Company Concentrated acetaminophen solution compositions
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
DE19631084A1 (de) * 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
US6294189B1 (en) * 1996-08-07 2001-09-25 De Novo, Inc. Method of forming decontaminant food product
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
EP1027036A2 (de) * 1997-10-03 2000-08-16 ELAN CORPORATION, Plc Geschmacksmaskierte formulierungen
SK262001A3 (en) * 1998-07-08 2001-09-11 Kirin Amgen Inc Powdery preparation for mucosal administration containing polymeric medicine
US6551617B1 (en) 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
ES2284643T3 (es) 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
KR100759720B1 (ko) * 2000-06-30 2007-10-04 아스텔라스세이야쿠 가부시키가이샤 구강내 속붕괴정
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
ATE401058T1 (de) 2001-11-01 2008-08-15 Nektar Therapeutics Sprühtrocknungsverfahren
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
DE10234165B4 (de) * 2002-07-26 2008-01-03 Advanced Micro Devices, Inc., Sunnyvale Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material
WO2004022037A1 (en) * 2002-09-04 2004-03-18 Ranbaxy Laboratories Limited Taste masked dosage forms and processes for their preparation
CA2508870C (en) 2002-12-30 2012-10-16 Nektar Therapeutics Prefilming atomizer
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
EP1694302A1 (de) 2003-12-15 2006-08-30 Council of Scientific and Industrial Research Geschmacksmaskierte pharmazeutische zusammensetzung mit bitter schmeckendem wirkstoff und einem ph-sensitiven polymer
JP2007518669A (ja) * 2003-12-15 2007-07-12 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ ｐＨ感受性ポリマーを含む風味マスクされる医薬組成物
US7972621B2 (en) * 2004-06-03 2011-07-05 R.P. Scherer Technologies, Llc Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US20060127479A1 (en) * 2004-10-08 2006-06-15 Natrajan Kumaraperumal Solvent free taste masked pharmaceutical compositions
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (de) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Geschmacksverdeckende pharmazeutische Zusammensetzungen mit magenlöslichen Porenbildnern
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
TW201127375A (en) * 2010-01-08 2011-08-16 Eurand Inc Taste masked topiramate composition and an orally disintegrating tablet comprising the same
EP2608773A4 (de) * 2010-08-24 2014-03-05 Univ Rutgers Formulierung und herstellung von arzneimitteln durch imprägnierung auf porösen trägern
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
CN102147195A (zh) * 2011-05-17 2011-08-10 苏州钻石金属粉有限公司 粉末冷却器
US9925138B2 (en) 2015-01-20 2018-03-27 Handa Pharmaceuticals, Llc Stable solid fingolimod dosage forms
EP3562486B1 (de) 2016-12-31 2024-03-13 Bioxcel Therapeutics, Inc. Verwendung von sublingualem dexmedetomidin zur behandlung von unruhe
EP3813802A4 (de) 2018-06-27 2022-06-08 Bioxcel Therapeutics, Inc. Filmformulierungen mit dexmedetomidin und verfahren zur herstellung davon
MX2022000709A (es) 2019-07-19 2022-05-19 Bioxcel Therapeutics Inc Regimenes de tratamiento con dexmedetomidina no sedante.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1322306A (en) * 1971-04-15 1973-07-04 Meiji Seika Co Stabilized antibiotic preparation and manufacturing process therefor
JPS5322141B2 (de) * 1972-12-14 1978-07-06
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
EP0040472B1 (de) * 1980-05-20 1986-01-29 Mallinckrodt, Inc. (a Delaware corporation) Trockenpulverisierte N-Acetyl-p-aminophenol-Zusammensetzungen und Verfahren zu deren Herstellung
US4562024A (en) * 1982-07-06 1985-12-31 Sterling Drug Inc. Process for preparing granulate containing poorly compressible medicinally active matter
US4631284A (en) * 1984-11-19 1986-12-23 Mallinckrodt, Inc. Acetaminophen compositions containing low doses of chlorpheniramine maleate, method for preparing same and tablets formed therefrom
DE3678640D1 (de) * 1985-08-26 1991-05-16 Procter & Gamble Geschmack abdeckende zusammensetzungen.

Also Published As

Publication number Publication date
ES2032450T3 (es) 1993-02-16
DE3770116D1 (de) 1991-06-20
CA1290251C (en) 1991-10-08
JPS63112513A (ja) 1988-05-17
AU7950987A (en) 1988-04-28
IE872751L (en) 1988-04-21
GR3002108T3 (en) 1992-12-30
EP0266113A1 (de) 1988-05-04
KR950013751B1 (ko) 1995-11-15
JP2542400B2 (ja) 1996-10-09
US4760093A (en) 1988-07-26
IE61952B1 (en) 1994-11-30
EP0266113B1 (de) 1991-05-15
AU594203B2 (en) 1990-03-01
KR880004804A (ko) 1988-06-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee