ATE62238T1 - Xanthon-derivate und verfahren zu ihrer herstellung. - Google Patents

Xanthon-derivate und verfahren zu ihrer herstellung.

Info

Publication number
ATE62238T1
ATE62238T1 AT85111907T AT85111907T ATE62238T1 AT E62238 T1 ATE62238 T1 AT E62238T1 AT 85111907 T AT85111907 T AT 85111907T AT 85111907 T AT85111907 T AT 85111907T AT E62238 T1 ATE62238 T1 AT E62238T1
Authority
AT
Austria
Prior art keywords
hydrogen atom
group
carboxyl group
carbon atoms
formula
Prior art date
Application number
AT85111907T
Other languages
English (en)
Inventor
Hiroshi Koga
Takashi Mori
Takashi Dan
Michitaka Akima
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59196796A external-priority patent/JPS6176476A/ja
Priority claimed from JP59204351A external-priority patent/JPS6183187A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE62238T1 publication Critical patent/ATE62238T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
AT85111907T 1984-09-21 1985-09-20 Xanthon-derivate und verfahren zu ihrer herstellung. ATE62238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59196796A JPS6176476A (ja) 1984-09-21 1984-09-21 キサントン誘導体
JP59204351A JPS6183187A (ja) 1984-09-28 1984-09-28 フロキサントン誘導体

Publications (1)

Publication Number Publication Date
ATE62238T1 true ATE62238T1 (de) 1991-04-15

Family

ID=26509990

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85111907T ATE62238T1 (de) 1984-09-21 1985-09-20 Xanthon-derivate und verfahren zu ihrer herstellung.

Country Status (6)

Country Link
US (2) US4661607A (de)
EP (1) EP0175376B1 (de)
AT (1) ATE62238T1 (de)
CA (1) CA1234126A (de)
DE (1) DE3582382D1 (de)
HU (2) HU200174B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
IT1261662B (it) * 1992-09-07 1996-05-28 Inverni Della Beffa Spa Derivati xantonici, loro preparazione ed attivita'
US5495005A (en) * 1993-08-26 1996-02-27 National Science Council Synthesis and pharmacological activity of a series of novel xanthone derivatives
US5977077A (en) * 1995-08-28 1999-11-02 Interlab Corporation Xanthone analogs for the treatment of infectious diseases
AU4515701A (en) 1999-12-02 2001-06-18 Interlab, Inc. Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins
EP1395596A2 (de) * 2001-05-18 2004-03-10 Board of Regents, The University of Texas System Methoden zur herstellung und verwendung von psorospermin-analoga
US6933396B2 (en) 2002-08-30 2005-08-23 Cylene Pharmaceuticals Process to prepare psorospermin
WO2009093255A2 (en) * 2008-01-21 2009-07-30 Ganga Raju Gokaraju A new nutraceutical composition from garcinia mangostana
US8673920B2 (en) * 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
CA2844310A1 (en) 2011-08-19 2013-02-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
TW201317213A (zh) 2011-09-16 2013-05-01 Merck Sharp & Dohme 腎外髓質鉀通道抑制劑
WO2013062900A1 (en) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013062892A1 (en) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013066718A2 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9108947B2 (en) 2011-10-31 2015-08-18 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
WO2013066714A1 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013090271A1 (en) 2011-12-16 2013-06-20 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
AR092031A1 (es) 2012-07-26 2015-03-18 Merck Sharp & Dohme Inhibidores del canal de potasio medular externo renal
EP2925322B1 (de) 2012-11-29 2018-10-24 Merck Sharp & Dohme Corp. Inhibitoren des renalen kaliumkanals der äusseren medulla
WO2014099633A2 (en) 2012-12-19 2014-06-26 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2014126944A2 (en) 2013-02-18 2014-08-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9765074B2 (en) 2013-03-15 2017-09-19 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP3027625B1 (de) 2013-07-31 2018-05-30 Merck Sharp & Dohme Corp. Zur behandlung von unter anderem bluthochdruck und akuter oder chronischer herzinsuffizienz geeignete spirokondensierte derivate von piperidin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE923132C (de) * 1952-06-29 1955-02-03 Mabeg Maschb G M B H Vorrichtung zum Vereinzeln und zum Zufuehren von Bogen aus Papier usw. an Druck-, Lackier- und Falzmaschinen
DE1172271B (de) * 1960-01-20 1964-06-18 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Xanthon-3-oxyessigsaeurealkylestern
FR1417961A (fr) * 1961-01-19 1965-11-19 Cassella Farbwerke Mainkur Ag Procédé de préparation de dérivés d'hydroxy-xanthones
BE757001A (fr) * 1969-10-10 1971-03-16 Cerpha Derives heterocycliques d'acides phenoxy acetique et leur preparation
IT1166191B (it) * 1979-12-12 1987-04-29 Medea Res Srl Acidi 2 xantonossi 2 metilpropionici loro esteri e loro sali caratterizzati da attivita ipolipemizzante

Also Published As

Publication number Publication date
EP0175376A3 (en) 1988-07-13
HU201076B (en) 1990-09-28
DE3582382D1 (de) 1991-05-08
HU896028D0 (en) 1990-02-28
EP0175376B1 (de) 1991-04-03
HU200174B (en) 1990-04-28
EP0175376A2 (de) 1986-03-26
US4661607A (en) 1987-04-28
US4816479A (en) 1989-03-28
CA1234126A (en) 1988-03-15
HUT41760A (en) 1987-05-28

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties