ATE17484T1 - Benzodioxan-imidazolin-verbindungen, verfahren zu deren herstellung und deren anwendung. - Google Patents

Benzodioxan-imidazolin-verbindungen, verfahren zu deren herstellung und deren anwendung.

Info

Publication number
ATE17484T1
ATE17484T1 AT82304072T AT82304072T ATE17484T1 AT E17484 T1 ATE17484 T1 AT E17484T1 AT 82304072 T AT82304072 T AT 82304072T AT 82304072 T AT82304072 T AT 82304072T AT E17484 T1 ATE17484 T1 AT E17484T1
Authority
AT
Austria
Prior art keywords
optionally substituted
lower alkyl
substituted phenyl
benzodioxane
preparation
Prior art date
Application number
AT82304072T
Other languages
English (en)
Inventor
Arthur Frederick Kluge
Arthur Martin Strosberg
Roger Lewis Whiting
George Allan Christie
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE17484T1 publication Critical patent/ATE17484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT82304072T 1981-08-03 1982-08-02 Benzodioxan-imidazolin-verbindungen, verfahren zu deren herstellung und deren anwendung. ATE17484T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/289,679 US4436914A (en) 1981-08-03 1981-08-03 Benzodioxane-imidazoline compounds as antihypertensives
EP82304072A EP0074711B1 (de) 1981-08-03 1982-08-02 Benzodioxan-imidazolin-Verbindungen, Verfahren zu deren Herstellung und deren Anwendung

Publications (1)

Publication Number Publication Date
ATE17484T1 true ATE17484T1 (de) 1986-02-15

Family

ID=23112603

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82304072T ATE17484T1 (de) 1981-08-03 1982-08-02 Benzodioxan-imidazolin-verbindungen, verfahren zu deren herstellung und deren anwendung.

Country Status (13)

Country Link
US (1) US4436914A (de)
EP (1) EP0074711B1 (de)
JP (1) JPS5849381A (de)
KR (1) KR840001160A (de)
AT (1) ATE17484T1 (de)
AU (1) AU8672582A (de)
CA (1) CA1185606A (de)
DE (1) DE3268541D1 (de)
DK (1) DK346082A (de)
ES (1) ES514634A0 (de)
IE (1) IE53246B1 (de)
NZ (1) NZ201449A (de)
ZA (1) ZA825576B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
IL95760A0 (en) * 1989-09-27 1992-05-25 Rhone Poulenc Sante Imidazole derivatives,their preparation and pharmaceutical compositions containing the same
GB9020889D0 (en) * 1990-09-25 1990-11-07 May & Baker Ltd New compositions of matter
US6162455A (en) * 1997-01-22 2000-12-19 American Cyanamid Company Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals
FR2766824B1 (fr) * 1997-07-30 1999-09-10 Adir Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR102491187B1 (ko) * 2022-09-05 2023-01-20 (주) 아하 제조원가를 낮춘 컨트롤 보드에 통합된 적산 전력계를 포함하는 전기차 충전 장치

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2979511A (en) 1959-03-25 1961-04-11 Olin Mathieson Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
US4302469A (en) * 1980-09-10 1981-11-24 Syntex (U.S.A.) Inc. 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
US4315021A (en) * 1980-12-03 1982-02-09 Syntex (U.S.A.) Inc. 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles

Also Published As

Publication number Publication date
DK346082A (da) 1983-02-04
US4436914A (en) 1984-03-13
ES8305758A1 (es) 1983-05-01
EP0074711A3 (en) 1983-04-27
IE821839L (en) 1983-02-03
KR840001160A (ko) 1984-03-28
EP0074711B1 (de) 1986-01-15
EP0074711A2 (de) 1983-03-23
JPS5849381A (ja) 1983-03-23
CA1185606A (en) 1985-04-16
DE3268541D1 (en) 1986-02-27
IE53246B1 (en) 1988-09-14
ZA825576B (en) 1984-03-28
ES514634A0 (es) 1983-05-01
AU8672582A (en) 1983-02-10
NZ201449A (en) 1986-01-24

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