ATE62224T1 - Verfahren zur herstellung von azetidinonzwischenprodukten. - Google Patents
Verfahren zur herstellung von azetidinonzwischenprodukten.Info
- Publication number
- ATE62224T1 ATE62224T1 AT86100281T AT86100281T ATE62224T1 AT E62224 T1 ATE62224 T1 AT E62224T1 AT 86100281 T AT86100281 T AT 86100281T AT 86100281 T AT86100281 T AT 86100281T AT E62224 T1 ATE62224 T1 AT E62224T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- intermediate products
- formula
- divalent metal
- heavy
- Prior art date
Links
- HONIICLYMWZJFZ-UHFFFAOYSA-N azetidine Chemical compound C1CNC1 HONIICLYMWZJFZ-UHFFFAOYSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 125000000962 organic group Chemical group 0.000 abstract 3
- 239000002184 metal Substances 0.000 abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001905 inorganic group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- HHXMXAQDOUCLDN-RXMQYKEDSA-N penem Chemical compound S1C=CN2C(=O)C[C@H]21 HHXMXAQDOUCLDN-RXMQYKEDSA-N 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858500831A GB8500831D0 (en) | 1985-01-14 | 1985-01-14 | Preparing azetidinone intermediates |
| EP86100281A EP0188247B1 (de) | 1985-01-14 | 1986-01-10 | Verfahren zur Herstellung von Azetidinonzwischenprodukten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE62224T1 true ATE62224T1 (de) | 1991-04-15 |
Family
ID=10572792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86100281T ATE62224T1 (de) | 1985-01-14 | 1986-01-10 | Verfahren zur herstellung von azetidinonzwischenprodukten. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4771134A (de) |
| EP (1) | EP0188247B1 (de) |
| JP (1) | JPH0699387B2 (de) |
| AT (1) | ATE62224T1 (de) |
| DE (2) | DE188247T1 (de) |
| GB (1) | GB8500831D0 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3752124T2 (de) * | 1986-01-17 | 1998-03-26 | Beecham Group Plc | Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung |
| JP3224412B2 (ja) * | 1992-03-30 | 2001-10-29 | サントリー株式会社 | 4−置換アゼチジノン誘導体の製造方法 |
| GB9307201D0 (en) * | 1993-04-06 | 1993-05-26 | Smithkline Beecham Plc | Novel process |
| DE102010004001A1 (de) | 2010-01-04 | 2011-07-07 | Sig Technology Ag | Verfahren und Vorrichtung zur Messung der abtötenden Wirksamkeit eines Entkeimungsmittels |
| JP2017527596A (ja) | 2014-09-19 | 2017-09-21 | コベストロ、ドイチュラント、アクチエンゲゼルシャフトCovestro Deutschland Ag | 気相中でイソシアネートを製造するための方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2343497A1 (de) * | 1972-06-22 | 1975-03-13 | Hoechst Ag | Verfahren zur herstellung von 4-mercapto-azetidinonen-(2) |
| US4378314A (en) * | 1979-09-21 | 1983-03-29 | Bristol Myers Company | Antibacterial agents and metal containing azetidinone intermediates therefore |
| JPS572291A (en) * | 1980-06-06 | 1982-01-07 | Sankyo Co Ltd | Penem-3-carboxylic derivative and its preparation |
| ZA815593B (en) * | 1980-08-16 | 1982-10-27 | Beecham Group Plc | Process for the preparation of 2-thio penem derivatives,certain of these compounds and intermediates therefor |
-
1985
- 1985-01-14 GB GB858500831A patent/GB8500831D0/en active Pending
-
1986
- 1986-01-10 AT AT86100281T patent/ATE62224T1/de not_active IP Right Cessation
- 1986-01-10 EP EP86100281A patent/EP0188247B1/de not_active Expired - Lifetime
- 1986-01-10 DE DE198686100281T patent/DE188247T1/de active Pending
- 1986-01-10 DE DE8686100281T patent/DE3678452D1/de not_active Expired - Lifetime
- 1986-01-13 US US06/818,235 patent/US4771134A/en not_active Expired - Lifetime
- 1986-01-13 JP JP61003703A patent/JPH0699387B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE188247T1 (de) | 1987-03-19 |
| EP0188247A1 (de) | 1986-07-23 |
| JPS61180766A (ja) | 1986-08-13 |
| EP0188247B1 (de) | 1991-04-03 |
| DE3678452D1 (de) | 1991-05-08 |
| JPH0699387B2 (ja) | 1994-12-07 |
| GB8500831D0 (en) | 1985-02-20 |
| US4771134A (en) | 1988-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |