ATE71086T1 - Verfahren zur herstellung von optischen aktiven 3-(methan-sulfonyloxy)thioland und analoge. - Google Patents

Verfahren zur herstellung von optischen aktiven 3-(methan-sulfonyloxy)thioland und analoge.

Info

Publication number
ATE71086T1
ATE71086T1 AT89303722T AT89303722T ATE71086T1 AT E71086 T1 ATE71086 T1 AT E71086T1 AT 89303722 T AT89303722 T AT 89303722T AT 89303722 T AT89303722 T AT 89303722T AT E71086 T1 ATE71086 T1 AT E71086T1
Authority
AT
Austria
Prior art keywords
preparation
thioland
sulfonyloxy
analogues
methane
Prior art date
Application number
AT89303722T
Other languages
English (en)
Inventor
Frank John Urban
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE71086T1 publication Critical patent/ATE71086T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AT89303722T 1988-04-19 1989-04-14 Verfahren zur herstellung von optischen aktiven 3-(methan-sulfonyloxy)thioland und analoge. ATE71086T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/183,102 US4874877A (en) 1988-04-19 1988-04-19 Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs

Publications (1)

Publication Number Publication Date
ATE71086T1 true ATE71086T1 (de) 1992-01-15

Family

ID=22671453

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89303722T ATE71086T1 (de) 1988-04-19 1989-04-14 Verfahren zur herstellung von optischen aktiven 3-(methan-sulfonyloxy)thioland und analoge.

Country Status (11)

Country Link
US (3) US4874877A (de)
EP (1) EP0338735B1 (de)
JP (1) JPH0637459B2 (de)
AT (1) ATE71086T1 (de)
DE (1) DE68900628D1 (de)
DK (1) DK185789A (de)
ES (1) ES2039851T3 (de)
FI (1) FI891845A (de)
GR (1) GR3003505T3 (de)
IE (1) IE891242L (de)
PT (1) PT90292B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874877A (en) * 1988-04-19 1989-10-17 Pfizer Inc. Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
EP0352977A3 (de) * 1988-07-28 1991-08-07 Pfizer Inc. Stereoselektives Oxydierungsverfahren
WO2001058864A1 (en) * 2000-02-07 2001-08-16 Rhone-Poulenc Animal Nutrition Process for the preparation of 2-hydroxy-4-methylthio butyric acid esters
US7485757B2 (en) 2004-09-14 2009-02-03 Sumitomo Chemical Company, Limited Method for Producing 4-(Methylthio) Butane-1,2-Diol
CN101040051B (zh) 2004-10-14 2012-02-01 住友化学株式会社 生产2-羟基-4-(甲硫基)丁酸的方法
WO2007032177A1 (ja) 2005-09-12 2007-03-22 Sumitomo Chemical Company, Limited ４−（メチルチオ）ブタン−１，２−ジオールの製造方法
PE20080940A1 (es) * 2006-06-28 2008-07-09 Pfizer Prod Inc Profarmacos de penem
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug
US7977078B2 (en) 2007-08-24 2011-07-12 Codexis, Inc. Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane
CN101348451B (zh) * 2008-09-05 2011-08-17 南京生命能科技开发有限公司 一种药用d,l-2-羟基-4-甲硫基丁酸钙的制备方法
BR112018000026A2 (pt) * 2015-07-02 2018-11-06 Board Of Regents Of The Univ Of Oklahoma tensoativos aniônicos
CN114341107A (zh) * 2019-09-06 2022-04-12 建明实业股份有限公司 通过酯化α-羟基酸制备α-羟基酯的工艺
CN114560796B (zh) * 2021-04-19 2024-09-20 广州浩和进出口有限公司 一种连续制备2-羟基-4-甲硫基丁酸酯的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU63168A1 (de) * 1971-05-14 1973-01-22
CA1030546A (en) * 1973-07-26 1978-05-02 Donald L. Schmidt 1-aryl cyclic sulfonium compounds, poly (aryl cyclic sulfonium) salts and modification of carboxy-containing polymers by treatment with cyclic sulfonium compounds
US4619924A (en) * 1984-05-18 1986-10-28 Pfizer Inc. 2-alkylthiopenem derivatives
US4482568A (en) * 1983-10-17 1984-11-13 University Of Iowa Research Foundation Inhibition of alcohol metabolism by tetramethylene sulfoxides
US4739047A (en) * 1985-10-17 1988-04-19 Pfizer Inc. Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
US4845219A (en) * 1986-07-30 1989-07-04 Takeda Chemical Industries, Ltd. Nitrogen- and sulfur-containing lipid compounds their production and use
US4874877A (en) * 1988-04-19 1989-10-17 Pfizer Inc. Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
US4864046A (en) * 1989-02-09 1989-09-05 Pfizer Inc. Process for optically active 3-thiolanyl sulfonate esters

Also Published As

Publication number Publication date
JPH0637459B2 (ja) 1994-05-18
FI891845A (fi) 1989-10-20
JPH026467A (ja) 1990-01-10
US4874877A (en) 1989-10-17
ES2039851T3 (es) 1993-10-01
DK185789D0 (da) 1989-04-18
IE891242L (en) 1989-10-19
DK185789A (da) 1989-10-20
US4954647A (en) 1990-09-04
EP0338735A1 (de) 1989-10-25
FI891845A0 (fi) 1989-04-18
DE68900628D1 (de) 1992-02-13
EP0338735B1 (de) 1992-01-02
PT90292A (pt) 1989-11-10
GR3003505T3 (de) 1993-03-16
US5326884A (en) 1994-07-05
PT90292B (pt) 1994-07-29

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee