ATE56709T1 - Phenylpyrazinderivate, verfahren zu deren herstellung, pharmazeutische zusammensetzung und verwendung. - Google Patents
Phenylpyrazinderivate, verfahren zu deren herstellung, pharmazeutische zusammensetzung und verwendung.Info
- Publication number
- ATE56709T1 ATE56709T1 AT86106311T AT86106311T ATE56709T1 AT E56709 T1 ATE56709 T1 AT E56709T1 AT 86106311 T AT86106311 T AT 86106311T AT 86106311 T AT86106311 T AT 86106311T AT E56709 T1 ATE56709 T1 AT E56709T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- phenylpyrazin
- manufacture
- pharmaceutical composition
- group
- Prior art date
Links
- LNJZJDLDXQQJSG-UHFFFAOYSA-N 2-phenylpyrazine Chemical class C1=CC=CC=C1C1=CN=CC=N1 LNJZJDLDXQQJSG-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60099382A JPH0665668B2 (ja) | 1985-05-10 | 1985-05-10 | フエニルピラジン誘導体および抗血栓剤 |
| EP86106311A EP0204172B1 (de) | 1985-05-10 | 1986-05-09 | Phenylpyrazinderivate, Verfahren zu deren Herstellung, pharmazeutische Zusammensetzung und Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE56709T1 true ATE56709T1 (de) | 1990-10-15 |
Family
ID=14245964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86106311T ATE56709T1 (de) | 1985-05-10 | 1986-05-09 | Phenylpyrazinderivate, verfahren zu deren herstellung, pharmazeutische zusammensetzung und verwendung. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4755514A (de) |
| EP (1) | EP0204172B1 (de) |
| JP (1) | JPH0665668B2 (de) |
| AT (1) | ATE56709T1 (de) |
| DE (1) | DE3674250D1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868183A (en) * | 1986-07-21 | 1989-09-19 | Otsuka Pharmaceutical Factory, Inc. | N-pyrazinyl substituted P-aminophenols |
| WO1989004308A1 (fr) * | 1987-11-12 | 1989-05-18 | Terumo Kabushiki Kaisha | Derives de pyrazine et preparation medicinale les contenant |
| US5304648A (en) * | 1992-09-29 | 1994-04-19 | Nestec S.A. | Pyrazine preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5843961A (ja) * | 1981-09-09 | 1983-03-14 | Ube Ind Ltd | 新規なピラジン誘導体及びその製造法 |
-
1985
- 1985-05-10 JP JP60099382A patent/JPH0665668B2/ja not_active Expired - Lifetime
-
1986
- 1986-05-09 US US06/861,314 patent/US4755514A/en not_active Expired - Fee Related
- 1986-05-09 EP EP86106311A patent/EP0204172B1/de not_active Expired - Lifetime
- 1986-05-09 AT AT86106311T patent/ATE56709T1/de not_active IP Right Cessation
- 1986-05-09 DE DE8686106311T patent/DE3674250D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0665668B2 (ja) | 1994-08-24 |
| DE3674250D1 (de) | 1990-10-25 |
| EP0204172A3 (en) | 1987-09-30 |
| EP0204172A2 (de) | 1986-12-10 |
| EP0204172B1 (de) | 1990-09-19 |
| US4755514A (en) | 1988-07-05 |
| JPS61257978A (ja) | 1986-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |