ATE547529T1 - Materialien und verfahren im zusammenhang mit verbesserten impfstrategien - Google Patents
Materialien und verfahren im zusammenhang mit verbesserten impfstrategienInfo
- Publication number
- ATE547529T1 ATE547529T1 AT08000554T AT08000554T ATE547529T1 AT E547529 T1 ATE547529 T1 AT E547529T1 AT 08000554 T AT08000554 T AT 08000554T AT 08000554 T AT08000554 T AT 08000554T AT E547529 T1 ATE547529 T1 AT E547529T1
- Authority
- AT
- Austria
- Prior art keywords
- materials
- vaccination strategies
- methods related
- epitopes
- improved vaccination
- Prior art date
Links
- 238000002255 vaccination Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0118532.1A GB0118532D0 (en) | 2001-07-30 | 2001-07-30 | Materials and methods relating to improved vaccination strategies |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE547529T1 true ATE547529T1 (de) | 2012-03-15 |
Family
ID=9919450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08000554T ATE547529T1 (de) | 2001-07-30 | 2002-07-30 | Materialien und verfahren im zusammenhang mit verbesserten impfstrategien |
Country Status (9)
Country | Link |
---|---|
US (2) | US20040234503A1 (de) |
EP (2) | EP1932915B1 (de) |
JP (2) | JP2005503375A (de) |
AT (1) | ATE547529T1 (de) |
AU (1) | AU2002319501A1 (de) |
CA (1) | CA2494304A1 (de) |
ES (1) | ES2381596T3 (de) |
GB (1) | GB0118532D0 (de) |
WO (2) | WO2003011331A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2469738A1 (en) | 2001-11-07 | 2003-08-07 | Mannkind Corporation | Expression vectors encoding epitopes of target-associated antigens and methods for their design |
EP2356999A1 (de) * | 2003-06-17 | 2011-08-17 | Mannkind Corporation | Zusammensetzung zur auslösung, verbesserung und erhaltung von Immunantworten gegen MHC klasse -I-beschränkte Epitope, für prophylaktische oder therapeutische zwecke |
CA2537931A1 (en) * | 2003-09-05 | 2005-03-24 | Dennis Panicali | Multi-antigen vectors for melanoma |
CA2594224A1 (en) * | 2004-12-29 | 2006-07-06 | Mannkind Corporation | Methods to elicit, enhance and sustain immune responses against mhc class i-restricted epitopes, for prophylactic or therapeutic purposes |
CN101687020A (zh) | 2005-06-17 | 2010-03-31 | 曼康公司 | 用于癌症的多价引发-和-增强免疫治疗剂 |
DK2040745T3 (da) | 2006-06-28 | 2013-03-18 | Statens Seruminstitut | Udvidelse af T-celle repertoiret til at omfatter subdominante epitoper ved vacci-nation med antigener leveret som proteinfragmenter eller peptidblandinger |
WO2009056535A2 (en) * | 2007-10-29 | 2009-05-07 | Genimmune N.V. | Methods and kits for inducing a ctl response using a prime boost regimen |
BRPI1006901A2 (pt) | 2009-01-20 | 2016-02-16 | Transgène S A | método ex vivo e kit para testar se um paciente responderá terapeuticamente a um método de tratamento, e, uso de níveis de sicam-1 em uma amostra de sangue |
NZ595290A (en) | 2009-03-24 | 2012-09-28 | Transgene Sa | Biomarker for monitoring patients |
CA2759050A1 (en) | 2009-04-17 | 2010-10-21 | Transgene Sa | Biomarker for monitoring patients |
JP5650212B2 (ja) | 2009-07-10 | 2015-01-07 | トランジェーヌ、ソシエテ、アノニムTransgene S.A. | 患者を選択するためのバイオマーカーおよび関連方法 |
GB201006405D0 (en) | 2010-04-16 | 2010-06-02 | Isis Innovation | Poxvirus expression system |
CA2801585C (en) | 2010-06-04 | 2017-10-03 | Flow Pharma Inc. | Peptide particle formulation |
EP2579884B1 (de) * | 2010-06-10 | 2014-06-04 | Intervet International B.V. | Antitumorzusammensetzung |
BR112017017949A2 (pt) | 2015-05-15 | 2018-04-10 | Curevac Ag | regimes de iniciação-reforço envolvendo administração de pelo menos um constructo de mrna |
IT201600101794A1 (it) | 2016-10-11 | 2018-04-11 | St Superiore Di Sanita | Sequenza nucleotidica esprimente una proteina ancorante esosomi per uso come vaccino. |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA754725B (en) | 1974-08-01 | 1976-06-30 | H Stickl | Preparation for the treatment of infectious diseases, method for the manufacture thereof, and its use |
US5110587A (en) | 1981-12-24 | 1992-05-05 | Health Research, Incorporated | Immunogenic composition comprising synthetically modified vaccinia virus |
GB8405530D0 (en) | 1984-03-02 | 1984-04-04 | Lysons R J | Vaccine for swine dysentery |
CA1341245C (en) | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
CH682669A5 (fr) | 1989-03-08 | 1993-10-29 | Health Research Inc | Virus recombinant modifié pour exprimer un produit de gènes chez un hôte, procédés et vaccin correspondants. |
US5225336A (en) | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
US5462734A (en) | 1990-11-02 | 1995-10-31 | Wisconsin Alumni Research Foundation | Bovine herpesvirus vaccine and method of using same |
US5766597A (en) | 1991-03-07 | 1998-06-16 | Virogenetics Corporation | Malaria recombinant poxviruses |
BE1004877A3 (fr) | 1991-05-27 | 1993-02-16 | Solvay | Virus de l'avipox recombinant, culture de cellules infectees par ce virus et vaccins pour la volaille derives de ce virus. |
EP1156102A1 (de) | 1991-06-14 | 2001-11-21 | Virogenetics Corporation | Rekombinanter hiv-spezifischer Impfstoff aus Poxvirus |
WO1993003145A1 (en) | 1991-07-26 | 1993-02-18 | Virogenetics Corporation | Infectious bursal disease virus recombinant poxvirus vaccine |
ATE181108T1 (de) | 1991-08-26 | 1999-06-15 | Immuno Ag | Direkt molekuläre klonierung eines modifizierten genoms eines chordopocken-virus |
DE69432730T2 (de) | 1993-08-11 | 2004-03-25 | Wyeth | Rekombinante Adenovirus-Vakzinen |
CA2195642A1 (en) | 1994-07-27 | 1996-02-08 | Andreas Suhrbier | Polyepitope vaccines |
US6001349A (en) | 1995-02-22 | 1999-12-14 | Therion Biologics Corporation | Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof |
US5635363A (en) | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
EP0753581A1 (de) | 1995-07-10 | 1997-01-15 | Immuno Ag | Verbesserte rekombinante eukaryotische zytoplasmatische Viren, Methode ihrer Herstellung und ihrer Verwendung als Impfstoffe |
US5741492A (en) | 1996-01-23 | 1998-04-21 | St. Jude Children's Research Hospital | Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses |
EP0877752B1 (de) * | 1996-01-23 | 2003-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Verfahren zur suche nach transdominanten effektorpeptiden und rna-molekülen |
US20010036928A1 (en) | 1996-04-22 | 2001-11-01 | Chamberlain Ronald S. | Heterologous boosting immunizations |
AU2678797A (en) | 1996-04-22 | 1997-11-12 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Heterologous boosting immunizations |
WO1998004728A1 (en) | 1996-07-25 | 1998-02-05 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
US6355252B1 (en) | 1997-02-21 | 2002-03-12 | Isis Innovation Ltd. | Soluble vaccinia virus protein that binds chemokines |
US20030138454A1 (en) | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
GB0023203D0 (en) | 2000-09-21 | 2000-11-01 | Isis Innovation | Vaccination method |
US6232445B1 (en) | 1997-10-29 | 2001-05-15 | Sunol Molecular Corporation | Soluble MHC complexes and methods of use thereof |
JP2002507393A (ja) | 1998-02-11 | 2002-03-12 | マキシジェン, インコーポレイテッド | 抗原ライブラリー免疫 |
AU765378B2 (en) | 1998-02-19 | 2003-09-18 | President And Fellows Of Harvard College | Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor |
ATE274354T1 (de) * | 1999-01-08 | 2004-09-15 | Wisconsin Alumni Res Found | Impfungsmethode zur effizienten induktion der t- lymphozyten zytotoxischantwort |
EP1200622A4 (de) | 1999-07-06 | 2004-12-22 | Merck & Co Inc | Hiv impfstoff aus einem das gag-gen tragenden adenovirus |
DE60016765T2 (de) | 1999-08-25 | 2005-11-24 | Merck & Co., Inc. | Synthetische papillomavirus gene, welche für expression in menschlichen zellen optimiert sind |
WO2001019408A1 (en) | 1999-09-16 | 2001-03-22 | Zycos Inc. | Nucleic acids encoding polyepitope polypeptides |
GB9922361D0 (en) * | 1999-09-21 | 1999-11-24 | Isis Innovation | Generating an immune response to an antigen |
AU7917200A (en) * | 1999-09-30 | 2001-04-30 | Institut Pasteur | Hybrid or chimeric polynucleotides, proteins, and compositions comprising hepatitis b virus sequences |
EP1232267B1 (de) * | 1999-10-27 | 2013-03-20 | Novartis Vaccines and Diagnostics, Inc. | Aktivierung von hcv-spezifischen t-zellen |
CA2408328C (en) | 2000-05-10 | 2012-04-17 | Aventis Pasteur Limited | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
CU23235A1 (es) | 2001-02-28 | 2007-09-26 | Ct Ingenieria Genetica Biotech | POXVIRUS RECOMBINANTES PARA PROTEINAS QUIMéRICAS DEL VIRUS DE LA INMUNODEFICIENCIA HUMANA Y SU APLICACION EN LA TERAPéUTICA Y LA PREVENCION DEL SIDA |
CN1164331C (zh) | 2001-05-23 | 2004-09-01 | 中国人民解放军第二军医大学 | 一种人乙型肝炎核酸疫苗 |
GB2396814B (en) | 2001-11-30 | 2006-07-19 | Isis Innovation | Fowlpox vector |
CA2537931A1 (en) | 2003-09-05 | 2005-03-24 | Dennis Panicali | Multi-antigen vectors for melanoma |
US20050175627A1 (en) | 2003-09-24 | 2005-08-11 | Oxxon Therapeutics Ltd. | HIV pharmaccines |
AU2004276559A1 (en) | 2003-09-24 | 2005-04-07 | Oxxon Therapeutics Limited | HIV pharmaccines |
GB2421025A (en) | 2004-12-09 | 2006-06-14 | Oxxon Therapeutics Ltd | HSV vaccination vectors |
WO2006120474A2 (en) | 2005-05-13 | 2006-11-16 | Oxxon Therapeutics Ltd | Compositions for inducing an immune response against tumor antigens |
WO2006125983A1 (en) | 2005-05-23 | 2006-11-30 | Oxxon Therapeutics Ltd | Compositions for inducing an immune response against hepatitis b |
-
2001
- 2001-07-30 GB GBGB0118532.1A patent/GB0118532D0/en not_active Ceased
-
2002
- 2002-07-30 US US10/485,074 patent/US20040234503A1/en not_active Abandoned
- 2002-07-30 EP EP08000554A patent/EP1932915B1/de not_active Expired - Lifetime
- 2002-07-30 WO PCT/GB2002/003496 patent/WO2003011331A2/en active Application Filing
- 2002-07-30 JP JP2003516561A patent/JP2005503375A/ja not_active Withdrawn
- 2002-07-30 CA CA002494304A patent/CA2494304A1/en not_active Abandoned
- 2002-07-30 AT AT08000554T patent/ATE547529T1/de active
- 2002-07-30 WO PCT/GB2002/003497 patent/WO2003011332A1/en not_active Application Discontinuation
- 2002-07-30 AU AU2002319501A patent/AU2002319501A1/en not_active Abandoned
- 2002-07-30 ES ES08000554T patent/ES2381596T3/es not_active Expired - Lifetime
- 2002-07-30 EP EP02749089A patent/EP1411974A2/de not_active Withdrawn
-
2008
- 2008-01-07 JP JP2008000225A patent/JP4896043B2/ja not_active Expired - Fee Related
- 2008-01-22 US US12/017,421 patent/US8282935B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2008142086A (ja) | 2008-06-26 |
US8282935B2 (en) | 2012-10-09 |
GB0118532D0 (en) | 2001-09-19 |
EP1932915A2 (de) | 2008-06-18 |
WO2003011331A3 (en) | 2003-09-25 |
US20040234503A1 (en) | 2004-11-25 |
ES2381596T3 (es) | 2012-05-29 |
EP1932915A3 (de) | 2009-04-01 |
US20080260780A1 (en) | 2008-10-23 |
CA2494304A1 (en) | 2003-02-13 |
WO2003011331A2 (en) | 2003-02-13 |
EP1932915B1 (de) | 2012-02-29 |
WO2003011332A1 (en) | 2003-02-13 |
JP2005503375A (ja) | 2005-02-03 |
AU2002319501A1 (en) | 2003-02-17 |
EP1411974A2 (de) | 2004-04-28 |
JP4896043B2 (ja) | 2012-03-14 |
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