ATE544867T1 - Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül - Google Patents

Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül

Info

Publication number
ATE544867T1
ATE544867T1 AT03813618T AT03813618T ATE544867T1 AT E544867 T1 ATE544867 T1 AT E544867T1 AT 03813618 T AT03813618 T AT 03813618T AT 03813618 T AT03813618 T AT 03813618T AT E544867 T1 ATE544867 T1 AT E544867T1
Authority
AT
Austria
Prior art keywords
specific interaction
sample
target molecule
electronic detection
active zone
Prior art date
Application number
AT03813618T
Other languages
English (en)
Inventor
Ulrich Bockelmann
Francois Pouthas
Cedric Gentil
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32669132&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE544867(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/FR2002/004283 external-priority patent/WO2003062811A1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE544867T1 publication Critical patent/ATE544867T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT03813618T 2002-12-11 2003-07-04 Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül ATE544867T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR2002/004283 WO2003062811A1 (fr) 2002-01-21 2002-12-11 Detection de molecules sondes fixees sur une zone active d'un capteur.
PCT/FR2003/002091 WO2004057027A1 (fr) 2002-12-11 2003-07-04 Procede de detection electronique d'au moins une interaction specifique entre des molecules sondes et des biomolecules cibles.

Publications (1)

Publication Number Publication Date
ATE544867T1 true ATE544867T1 (de) 2012-02-15

Family

ID=32669132

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03813618T ATE544867T1 (de) 2002-12-11 2003-07-04 Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül

Country Status (6)

Country Link
US (1) US7908088B2 (de)
EP (1) EP1570091B1 (de)
JP (1) JP4832759B2 (de)
AT (1) ATE544867T1 (de)
AU (1) AU2003260662A1 (de)
WO (1) WO2004057027A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2835058B1 (fr) * 2002-01-21 2004-03-12 Centre Nat Rech Scient Procede de detection d'au moins un parametre caracteristique de molecules sondes fixees sur au moins une zone active d'un capteur
KR20050087955A (ko) * 2004-02-27 2005-09-01 삼성전자주식회사 드바이 길이 조절에 의한 바이오 ｆｅｔ를 이용한 바이오분자의 검출 방법
WO2005095938A1 (en) * 2004-04-01 2005-10-13 Nanyang Technological University Addressable transistor chip for conducting assays
US20080108164A1 (en) * 2006-11-06 2008-05-08 Oleynik Vladislav A Sensor System and Method
WO2008154225A2 (en) * 2007-06-06 2008-12-18 Bayer Healthcare Llc Microdeposition system for a biosensor
KR101465961B1 (ko) * 2007-10-09 2014-12-01 삼성전자주식회사 유전자 검출 방법 및 장치
KR100969667B1 (ko) * 2008-03-24 2010-07-14 디지탈 지노믹스(주) 생리활성물질을 전기적으로 검출하는 방법 및 이를 위한바이오칩
US20100035252A1 (en) * 2008-08-08 2010-02-11 Ion Torrent Systems Incorporated Methods for sequencing individual nucleic acids under tension
WO2013154750A1 (en) 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
WO2010132263A2 (en) * 2009-05-15 2010-11-18 University Of Florida Research Foundation Inc. Wireless based marine pathogens detection system
US9029132B2 (en) * 2009-08-06 2015-05-12 International Business Machines Corporation Sensor for biomolecules
FR2949120A1 (fr) 2009-08-13 2011-02-18 Centre Nat Rech Scient Procede de detection d'un adn circularise et utilisation de ce procede pour la detection de mutations
US8052931B2 (en) 2010-01-04 2011-11-08 International Business Machines Corporation Ultra low-power CMOS based bio-sensor circuit
US9068935B2 (en) * 2010-04-08 2015-06-30 International Business Machines Corporation Dual FET sensor for sensing biomolecules and charged ions in an electrolyte
EP3444600B1 (de) 2011-01-11 2020-05-13 The Trustees of Columbia University in the City of New York System und verfahren zur einzelmoleküldetektion mithilfe von nanoröhrchen
WO2012116161A1 (en) 2011-02-23 2012-08-30 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule detection using nanopores
WO2013158280A1 (en) * 2012-04-20 2013-10-24 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule nucleic-acid assay platforms
GB202017861D0 (en) 2020-11-12 2020-12-30 Ulifetec Sas Method
WO2023164157A1 (en) * 2022-02-25 2023-08-31 Cardea Bio, Inc. Integrated circuit chip with 2d field-effect transistors and on-chip thin film layer deposition with electrical characterization

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4238757A (en) * 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
EP0213825A3 (de) * 1985-08-22 1989-04-26 Molecular Devices Corporation Chemisch-modulierte Mehrfachkapazitanz
US5242793A (en) * 1989-03-08 1993-09-07 Kanzaki Paper Manufacturing Co., Ltd. Selective permeable membrane and electrode using the same
US5498521A (en) * 1990-01-24 1996-03-12 President And Fellows Of Harvard College Diagnosis of hereditary retinal degenerative diseases
GB2278235B (en) * 1991-10-21 1996-05-08 Holm Kennedy James W Method and device for biochemical sensing
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
US6331274B1 (en) * 1993-11-01 2001-12-18 Nanogen, Inc. Advanced active circuits and devices for molecular biological analysis and diagnostics
US6127127A (en) * 1995-06-27 2000-10-03 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5805014A (en) * 1996-03-01 1998-09-08 Compaq Computer Corporation System having active pull-down circuit and method
JP2001511245A (ja) * 1996-04-17 2001-08-07 モトローラ・インコーポレイテッド トランジスタによる分子検出装置および方法
US5827482A (en) * 1996-08-20 1998-10-27 Motorola Corporation Transistor-based apparatus and method for molecular detection and field enhancement
US6322963B1 (en) * 1998-06-15 2001-11-27 Biosensor Systems Design., Inc. Sensor for analyte detection
JP4137239B2 (ja) * 1998-08-03 2008-08-20 株式会社堀場製作所 Ｉｓｆｅｔアレイ
US6281006B1 (en) * 1998-08-24 2001-08-28 Therasense, Inc. Electrochemical affinity assay
IL130326A0 (en) 1999-06-07 2000-06-01 Yeda Res & Dev A sensor based on molecular controlled semiconductor resistor
JP4587539B2 (ja) * 1999-09-13 2010-11-24 アイメック 有機材料に基づいてサンプル中の被分析物を検出するための装置
US6916614B1 (en) * 1999-10-20 2005-07-12 Tum Gene, Inc. Gene detecting chip, detector, and detecting method
US6875619B2 (en) * 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
JP2001165894A (ja) * 1999-12-08 2001-06-22 Fuji Photo Film Co Ltd 縫い込み型インターカレータ、核酸断片の検出方法、及び核酸断片の検出キット
US6489160B2 (en) * 2000-03-16 2002-12-03 Kabushiki Kaisha Toshiba Method for producing nucleic acid strand immobilized carrier
FR2810905B1 (fr) * 2000-06-30 2003-05-16 Inst Curie Additif pour minimiser les phenomenes d'adsorption et/ou d'electroosmose
KR20080005303A (ko) * 2000-12-11 2008-01-10 프레지던트 앤드 펠로우즈 오브 하버드 칼리지 나노센서
JP2002221510A (ja) * 2001-01-26 2002-08-09 Japan Science & Technology Corp 蓄積型化学・物理現象検出装置
EP1423687A1 (de) * 2001-08-08 2004-06-02 The Arizona Board of Regents Nukleinsäure-feldeffekttransistor
JP3946701B2 (ja) * 2001-12-19 2007-07-18 株式会社日立ハイテクノロジーズ ポテンシオメトリックｄｎａマイクロアレイ、その製造方法、及び核酸解析方法
DE10163599B4 (de) 2001-12-21 2006-06-29 Micronas Gmbh Verfahren zur Bestimmung von Nukleinsäureanalyten

Also Published As

Publication number Publication date
JP2006510025A (ja) 2006-03-23
EP1570091B1 (de) 2012-02-08
JP4832759B2 (ja) 2011-12-07
AU2003260662A1 (en) 2004-07-14
WO2004057027A1 (fr) 2004-07-08
US20060246443A1 (en) 2006-11-02
EP1570091A1 (de) 2005-09-07
US7908088B2 (en) 2011-03-15

Similar Documents

Publication Publication Date Title
ATE544867T1 (de) Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül
WO2010047804A8 (en) Integrated sensor arrays for biological and chemical analysis
TW200626891A (en) Nucleic acid detecting sensor, nucleic acid detecting chip, and nucleic acid detecting circuit
BRPI0519119A2 (pt) sistema colorimÉtrico e mÉtodo para detectar um analito
WO2004106891A3 (en) Ultrasensitive biochemical sensor
ATE538214T1 (de) Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen
DE60035459D1 (de) Automatisierte Echtzeit-Analyse von Nukleinsäureamplifikation
ATE366321T1 (de) Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind
DE60128279D1 (de) Optischer Sensor zum Nachweis mehrerer Analyte
WO2009158006A3 (en) Methods and apparatus for detecting molecular interactions using fet arrays
WO2007038754A3 (en) Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
ATE245937T1 (de) Überwachung physiologischer analyte
ATE330038T1 (de) Nukleinsäure-biosensor
ATE477338T1 (de) Vorrichtung und verfahren zum nachweis von molekularen wechselwirkungen
WO2005043160A3 (en) Ultrasensitive biochemical sensing platform
ATE525462T1 (de) Proteomanalyseverfahren für phosphoryliertes protein
DK2038430T3 (da) Toll-Like-Receptor-4-dysfunktion og de biologiske anvendelser deraf
ATE538382T1 (de) Sequentieller optischer nachweis von einem array mit getrenntentestzonen
SE0800871L (sv) Analysförfarande och anordning
DE50213056D1 (de) Sensoranordnung, vorrichtung und verfahren zur ampologischen wirkort- und/oder wirkstofftestung
FR2902441B1 (fr) Procede de determination de la concentration d'acides nucleiques
JP2006510025A5 (de)
ES2188997T3 (es) Deteccion e identificacion de enterovirus no poliovirus.
ATE503021T1 (de) Verfahren zum nachweis von endoglykosidase aktivität