ATE544849T1 - Aktivierte dendritische zellen, therapieverfahren unter verwendung der dendritischen zellen sowie verfahren zur kultivierung von gamma-delta-t- zellen - Google Patents
Aktivierte dendritische zellen, therapieverfahren unter verwendung der dendritischen zellen sowie verfahren zur kultivierung von gamma-delta-t- zellenInfo
- Publication number
- ATE544849T1 ATE544849T1 AT05760126T AT05760126T ATE544849T1 AT E544849 T1 ATE544849 T1 AT E544849T1 AT 05760126 T AT05760126 T AT 05760126T AT 05760126 T AT05760126 T AT 05760126T AT E544849 T1 ATE544849 T1 AT E544849T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- dendritic cells
- dendritic cell
- cultivation
- gamma delta
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 8
- 210000004027 cell Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 210000004443 dendritic cell Anatomy 0.000 abstract 4
- 230000003213 activating effect Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000002659 cell therapy Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 210000001616 monocyte Anatomy 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Developmental Biology & Embryology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004229991 | 2004-07-08 | ||
| PCT/JP2005/012971 WO2006006638A1 (ja) | 2004-07-08 | 2005-07-07 | 樹状細胞、該樹状細胞を含む医薬、該樹状細胞を用いた治療方法およびγδＴ細胞の培養方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE544849T1 true ATE544849T1 (de) | 2012-02-15 |
Family
ID=35783974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05760126T ATE544849T1 (de) | 2004-07-08 | 2005-07-07 | Aktivierte dendritische zellen, therapieverfahren unter verwendung der dendritischen zellen sowie verfahren zur kultivierung von gamma-delta-t- zellen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8513010B2 (de) |
| EP (1) | EP1788078B1 (de) |
| JP (2) | JPWO2006006638A1 (de) |
| KR (1) | KR101217706B1 (de) |
| AT (1) | ATE544849T1 (de) |
| AU (1) | AU2005260887B2 (de) |
| DK (1) | DK1788078T3 (de) |
| ES (1) | ES2379088T3 (de) |
| WO (1) | WO2006006638A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1788078B1 (de) * | 2004-07-08 | 2012-02-08 | Medinet., Co. Ltd. | Aktivierte dendritische zellen, therapieverfahren unter verwendung der dendritischen zellen sowie verfahren zur kultivierung von gamma-delta-t-zellen |
| ES2391573T3 (es) | 2005-09-08 | 2012-11-27 | Medinet Co., Ltd. | Método para el tratamiento de activación de una célula presentadora de antígeno |
| JPWO2008111430A1 (ja) * | 2007-03-09 | 2010-06-24 | タカラバイオ株式会社 | γδＴ細胞集団の製造方法 |
| US20090015814A1 (en) | 2007-07-11 | 2009-01-15 | Carl Zeiss Smt Ag | Detector for registering a light intensity, and illumination system equipped with the detector |
| HUE027084T2 (en) | 2008-07-01 | 2016-08-29 | Medinet Co Ltd | Method for simultaneous induction of CTL and gamma delta T cells |
| US10188733B2 (en) | 2010-10-22 | 2019-01-29 | President And Fellows Of Harvard College | Vaccines comprising bisphosphonate and methods of use thereof |
| JP6577795B2 (ja) | 2014-09-03 | 2019-09-18 | 日東電工株式会社 | ビスホスホネート剤を含む細胞性免疫用ワクチン医薬組成物 |
| US10471141B2 (en) | 2014-09-03 | 2019-11-12 | Nitto Denko Corporation | Bisphosphonate-containing vaccine pharmaceutical composition for humoral immunity |
| CN106754707A (zh) * | 2017-02-16 | 2017-05-31 | 南京市儿童医院 | 一种肠γδT细胞的分离方法 |
| CN108513973A (zh) * | 2018-05-30 | 2018-09-11 | 广州沙艾生物科技有限公司 | 一种免疫细胞的储存方法及细胞冻存液 |
| CN110184240B (zh) * | 2019-06-13 | 2020-11-20 | 上海市肺科医院 | 一种高效扩增活化Vγ2Vδ2 T细胞增强其抗结核活性的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6821778B1 (en) * | 1993-12-01 | 2004-11-23 | The Board Of Trustees Of Leland Stanford Junior University | Methods for using dendritic cells to activate gamma/delta-T cell receptor-positive T cells |
| US6495333B1 (en) | 1998-09-22 | 2002-12-17 | Becton Dickinson And Company | Flow cytometric, whole blood dendritic cell immune function assay |
| AU7867400A (en) | 1999-10-08 | 2001-04-23 | Dendreon Corporation | Generation and characterization of a dendritic cell isolated from human peripheral blood mononuclear cells |
| US7090865B2 (en) * | 2001-11-29 | 2006-08-15 | National Jewish Medical And Research Center | Composition and method for treating autoimmune hemolytic anemia |
| US20050048646A1 (en) * | 2003-08-25 | 2005-03-03 | Medinet Co., Ltd. | Method for inducing cytotoxic T lymphocyte |
| EP1788078B1 (de) * | 2004-07-08 | 2012-02-08 | Medinet., Co. Ltd. | Aktivierte dendritische zellen, therapieverfahren unter verwendung der dendritischen zellen sowie verfahren zur kultivierung von gamma-delta-t-zellen |
| ES2391573T3 (es) * | 2005-09-08 | 2012-11-27 | Medinet Co., Ltd. | Método para el tratamiento de activación de una célula presentadora de antígeno |
| HUE027084T2 (en) * | 2008-07-01 | 2016-08-29 | Medinet Co Ltd | Method for simultaneous induction of CTL and gamma delta T cells |
| WO2011096504A1 (ja) * | 2010-02-08 | 2011-08-11 | 株式会社日本バイオセラピー研究所 | Nk細胞強化型血液製剤の製造方法 |
-
2005
- 2005-07-07 EP EP05760126A patent/EP1788078B1/de active Active
- 2005-07-07 AU AU2005260887A patent/AU2005260887B2/en active Active
- 2005-07-07 DK DK05760126.2T patent/DK1788078T3/da active
- 2005-07-07 AT AT05760126T patent/ATE544849T1/de active
- 2005-07-07 WO PCT/JP2005/012971 patent/WO2006006638A1/ja active Application Filing
- 2005-07-07 US US11/631,660 patent/US8513010B2/en active Active
- 2005-07-07 ES ES05760126T patent/ES2379088T3/es active Active
- 2005-07-07 KR KR1020077003050A patent/KR101217706B1/ko active IP Right Grant
- 2005-07-07 JP JP2006529100A patent/JPWO2006006638A1/ja not_active Withdrawn
-
2012
- 2012-07-06 JP JP2012151970A patent/JP5156137B2/ja active Active
-
2013
- 2013-07-15 US US13/942,631 patent/US20130302302A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130302302A1 (en) | 2013-11-14 |
| KR101217706B1 (ko) | 2013-01-02 |
| AU2005260887B2 (en) | 2010-07-08 |
| WO2006006638A1 (ja) | 2006-01-19 |
| ES2379088T3 (es) | 2012-04-20 |
| US8513010B2 (en) | 2013-08-20 |
| KR20070060075A (ko) | 2007-06-12 |
| EP1788078A1 (de) | 2007-05-23 |
| JPWO2006006638A1 (ja) | 2008-05-01 |
| DK1788078T3 (da) | 2012-04-23 |
| US20070190169A1 (en) | 2007-08-16 |
| JP5156137B2 (ja) | 2013-03-06 |
| EP1788078A4 (de) | 2009-03-04 |
| EP1788078B1 (de) | 2012-02-08 |
| JP2012191952A (ja) | 2012-10-11 |
| AU2005260887A1 (en) | 2006-01-19 |
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