ATE538381T1 - Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen - Google Patents

Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen

Info

Publication number
ATE538381T1
ATE538381T1 AT01901846T AT01901846T ATE538381T1 AT E538381 T1 ATE538381 T1 AT E538381T1 AT 01901846 T AT01901846 T AT 01901846T AT 01901846 T AT01901846 T AT 01901846T AT E538381 T1 ATE538381 T1 AT E538381T1
Authority
AT
Austria
Prior art keywords
aluminum
enzyme immunoassay
determining
antigen content
total antigen
Prior art date
Application number
AT01901846T
Other languages
English (en)
Inventor
Cristy Dougherty
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Application granted granted Critical
Publication of ATE538381T1 publication Critical patent/ATE538381T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01901846T 2000-01-07 2001-01-08 Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen ATE538381T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17508600P 2000-01-07 2000-01-07
PCT/US2001/000498 WO2001051926A2 (en) 2000-01-07 2001-01-08 Competitive enzyme immunoassay for assessing total antigen content of aluminum-adsorbed antigens

Publications (1)

Publication Number Publication Date
ATE538381T1 true ATE538381T1 (de) 2012-01-15

Family

ID=22638819

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01901846T ATE538381T1 (de) 2000-01-07 2001-01-08 Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen

Country Status (6)

Country Link
US (1) US20040033545A1 (de)
EP (2) EP2343552A1 (de)
AT (1) ATE538381T1 (de)
AU (1) AU2770001A (de)
CA (1) CA2394151A1 (de)
WO (1) WO2001051926A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7867715B2 (en) 2003-08-05 2011-01-11 Alk-Abello A/S Method of evaluating the immunological activity of a vaccine
CN1307422C (zh) * 2005-01-31 2007-03-28 上海市血液中心 一种质控品稀释液及其形成的质控品
ATE466043T1 (de) * 2006-10-04 2010-05-15 Borealis Tech Oy Migrationsarme polyolefinzusammensetzung
PT2705365T (pt) * 2011-01-14 2016-09-19 Hal Allergy Holding B V Imunoensaio para determinação direta do teor de antigénio de produtos compreendendo partículas de antigénio acoplado a adjuvante
CN105928771B (zh) * 2016-04-08 2019-01-18 西藏恒久投资有限公司 一种检测疫苗抗原含量的样品前处理方法
RU2715899C1 (ru) * 2019-02-21 2020-03-04 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) Способ количественного определения в вакцинном препарате антигена, адсорбированного на частицах гидроксида алюминия
CN110554188A (zh) * 2019-10-23 2019-12-10 北京智飞绿竹生物制药有限公司 一种佐剂吸附组分疫苗含量的检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894444A (en) 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
SU1746318A1 (ru) * 1990-06-05 1992-07-07 Институт полиомиелита и вирусных энцефалитов Способ определени концентрации белка Е вируса клещевого энцефалита в препаратах вакцины, сорбированных на гидроокиси алюмини
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
DE4232073C2 (de) * 1992-09-25 2001-09-20 Chiron Behring Gmbh & Co Verfahren zur immunchemischen Quantifizierung von inaktivierten, immunreaktiven Antigenen

Also Published As

Publication number Publication date
AU2770001A (en) 2001-07-24
US20040033545A1 (en) 2004-02-19
EP2343552A1 (de) 2011-07-13
CA2394151A1 (en) 2001-07-19
WO2001051926A3 (en) 2002-02-21
WO2001051926A2 (en) 2001-07-19
EP1244913A2 (de) 2002-10-02
EP1244913B1 (de) 2011-12-21

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