ATE538381T1 - Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen - Google Patents
Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenenInfo
- Publication number
- ATE538381T1 ATE538381T1 AT01901846T AT01901846T ATE538381T1 AT E538381 T1 ATE538381 T1 AT E538381T1 AT 01901846 T AT01901846 T AT 01901846T AT 01901846 T AT01901846 T AT 01901846T AT E538381 T1 ATE538381 T1 AT E538381T1
- Authority
- AT
- Austria
- Prior art keywords
- aluminum
- enzyme immunoassay
- determining
- antigen content
- total antigen
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 5
- 102000036639 antigens Human genes 0.000 title abstract 5
- 108091007433 antigens Proteins 0.000 title abstract 5
- 230000002860 competitive effect Effects 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052782 aluminium Inorganic materials 0.000 title abstract 2
- 238000003018 immunoassay Methods 0.000 title abstract 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 238000003795 desorption Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17508600P | 2000-01-07 | 2000-01-07 | |
| PCT/US2001/000498 WO2001051926A2 (en) | 2000-01-07 | 2001-01-08 | Competitive enzyme immunoassay for assessing total antigen content of aluminum-adsorbed antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE538381T1 true ATE538381T1 (de) | 2012-01-15 |
Family
ID=22638819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01901846T ATE538381T1 (de) | 2000-01-07 | 2001-01-08 | Kompetitiver enzym-immunoassay zur bestimmung des totalen antigen-gehaltes von auf aluminium adsorbierten antigenen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040033545A1 (de) |
| EP (2) | EP2343552A1 (de) |
| AT (1) | ATE538381T1 (de) |
| AU (1) | AU2770001A (de) |
| CA (1) | CA2394151A1 (de) |
| WO (1) | WO2001051926A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7867715B2 (en) | 2003-08-05 | 2011-01-11 | Alk-Abello A/S | Method of evaluating the immunological activity of a vaccine |
| CN1307422C (zh) * | 2005-01-31 | 2007-03-28 | 上海市血液中心 | 一种质控品稀释液及其形成的质控品 |
| ES2340515T3 (es) * | 2006-10-04 | 2010-06-04 | Borealis Technology Oy | Composiciones de poliolefina de baja migracion. |
| DK2705365T3 (en) * | 2011-01-14 | 2016-10-24 | Hal Allergy Holding B V | Immunoassay for the direct determination of the antigen content in the products containing the adjuvant-linked antigen particles |
| CN105928771B (zh) * | 2016-04-08 | 2019-01-18 | 西藏恒久投资有限公司 | 一种检测疫苗抗原含量的样品前处理方法 |
| RU2715899C1 (ru) * | 2019-02-21 | 2020-03-04 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) | Способ количественного определения в вакцинном препарате антигена, адсорбированного на частицах гидроксида алюминия |
| CN110554188A (zh) * | 2019-10-23 | 2019-12-10 | 北京智飞绿竹生物制药有限公司 | 一种佐剂吸附组分疫苗含量的检测方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894444A (en) | 1987-07-16 | 1990-01-16 | Merck & Co., Inc. | Recovery and purification of immunogens from immunogen-alum complexes |
| SU1746318A1 (ru) * | 1990-06-05 | 1992-07-07 | Институт полиомиелита и вирусных энцефалитов | Способ определени концентрации белка Е вируса клещевого энцефалита в препаратах вакцины, сорбированных на гидроокиси алюмини |
| US5980909A (en) * | 1991-02-15 | 1999-11-09 | Uab Research Foundation | Epitopic regions of pneumococcal surface protein A |
| DE4232073C2 (de) * | 1992-09-25 | 2001-09-20 | Chiron Behring Gmbh & Co | Verfahren zur immunchemischen Quantifizierung von inaktivierten, immunreaktiven Antigenen |
-
2001
- 2001-01-08 AT AT01901846T patent/ATE538381T1/de active
- 2001-01-08 CA CA002394151A patent/CA2394151A1/en not_active Abandoned
- 2001-01-08 US US10/148,978 patent/US20040033545A1/en not_active Abandoned
- 2001-01-08 EP EP10012197A patent/EP2343552A1/de not_active Withdrawn
- 2001-01-08 WO PCT/US2001/000498 patent/WO2001051926A2/en not_active Ceased
- 2001-01-08 AU AU27700/01A patent/AU2770001A/en not_active Abandoned
- 2001-01-08 EP EP01901846A patent/EP1244913B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1244913A2 (de) | 2002-10-02 |
| EP1244913B1 (de) | 2011-12-21 |
| CA2394151A1 (en) | 2001-07-19 |
| AU2770001A (en) | 2001-07-24 |
| WO2001051926A2 (en) | 2001-07-19 |
| US20040033545A1 (en) | 2004-02-19 |
| EP2343552A1 (de) | 2011-07-13 |
| WO2001051926A3 (en) | 2002-02-21 |
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