ATE538109T1 - Neue für die behandlung von obesitas und diabetes geeignete 2-(2-hydroxyphenyl)benzothiadiazine - Google Patents
Neue für die behandlung von obesitas und diabetes geeignete 2-(2-hydroxyphenyl)benzothiadiazineInfo
- Publication number
- ATE538109T1 ATE538109T1 AT07822643T AT07822643T ATE538109T1 AT E538109 T1 ATE538109 T1 AT E538109T1 AT 07822643 T AT07822643 T AT 07822643T AT 07822643 T AT07822643 T AT 07822643T AT E538109 T1 ATE538109 T1 AT E538109T1
- Authority
- AT
- Austria
- Prior art keywords
- obesity
- diabetes
- treatment
- benzothiadiazine
- hydroxyphenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Child & Adolescent Psychology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200601488 | 2006-11-15 | ||
PCT/EP2007/062408 WO2008059025A1 (en) | 2006-11-15 | 2007-11-15 | Novel 2-(2-hydroxyphenyl) benzothiadiazines useful for treating obesity and diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE538109T1 true ATE538109T1 (de) | 2012-01-15 |
Family
ID=39016016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07822643T ATE538109T1 (de) | 2006-11-15 | 2007-11-15 | Neue für die behandlung von obesitas und diabetes geeignete 2-(2-hydroxyphenyl)benzothiadiazine |
Country Status (6)
Country | Link |
---|---|
US (1) | US8022066B2 (de) |
EP (1) | EP2086951B1 (de) |
AT (1) | ATE538109T1 (de) |
CA (1) | CA2669874A1 (de) |
ES (1) | ES2377322T3 (de) |
WO (1) | WO2008059025A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2669884A1 (en) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | Novel 2-(2-hydroxyphenyl)benzimidazoles useful for treating obesity and diabetes |
CA2669860A1 (en) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | New haloalkylsulfone substituted compounds useful for treating obesity and diabetes |
EP2567959B1 (de) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren |
EP3565806B1 (de) | 2017-01-06 | 2022-03-02 | Rivus Pharmaceuticals, Inc. | Neue phenylderivate |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3251837A (en) | 1962-09-14 | 1966-05-17 | Pfizer & Co C | Derivatives of 1, 2, 4-benzothiadiazine-1, 1-dioxides |
US3269955A (en) | 1963-05-10 | 1966-08-30 | American Cyanamid Co | Method for emitting fluorescent light using fluorescent quinazolones |
US3526627A (en) | 1969-06-05 | 1970-09-01 | American Cyanamid Co | Method for preparation of quinazolones |
JPS6025984A (ja) | 1983-07-22 | 1985-02-08 | Tokyo Inst Of Technol | ベンゾチアジアジン誘導体の製造方法 |
US5240962A (en) | 1991-04-15 | 1993-08-31 | Takasago Institute For Interdisciplinary Science, Inc. | Antiobesity and fat-reducing agents |
EP0876379A1 (de) | 1996-01-17 | 1998-11-11 | Novo Nordisk A/S | Kondensierte 1,2,4-thiadiazin- und 1,4-thiazinderivate, deren herstellung und verwendung |
AU2995497A (en) | 1996-07-26 | 1997-11-19 | Dr. Reddy's Research Foundation | Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof |
PT944648E (pt) | 1996-08-30 | 2007-06-26 | Novo Nordisk As | Derivados do glp-1. |
AU4345297A (en) | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
CN1190434C (zh) | 1996-12-31 | 2005-02-23 | 雷迪实验室有限公司 | 新的杂环化合物、其制备方法和含有它们的药物组合物及其在治疗糖尿病和相关疾病中的应用 |
AU2930797A (en) | 1997-05-02 | 1997-11-19 | Dr. Reddy's Research Foundation | Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
JP2003514508A (ja) | 1997-07-01 | 2003-04-15 | ノボ ノルディスク アクティーゼルスカブ | グルカゴン拮抗剤/逆作用剤 |
US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
RU2215004C2 (ru) | 1997-07-16 | 2003-10-27 | Ново Нордиск А/С | Конденсированное производное 1,2,4-тиадиазина, фармацевтическая композиция и способ получения лекарственного препарата |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
WO1999019313A1 (en) | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
DE69803750T2 (de) | 1997-12-02 | 2002-09-12 | Reddy S Res Foundation Andhra | Thiazolidinedione- und oxazolidinedione-derivate mit antidiabetischen, hypolipidämischen und anti hypertensiven eigenschaften |
JP2002527503A (ja) | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
WO2000023425A1 (en) | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
AU6325599A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
EP1123268A1 (de) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Neuartige vebindungen, ihre herstellung und ihre verwendung |
US6353018B1 (en) | 1998-10-21 | 2002-03-05 | Novo Nordisk A/S | Compounds, their preparation and use |
WO2000023451A1 (en) | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
AU1649900A (en) | 1998-12-18 | 2000-07-12 | Novo Nordisk A/S | Fused 1,2,4-thiadiazine derivatives, their preparation and use |
WO2000041121A1 (en) | 1999-01-07 | 2000-07-13 | Ccrewards.Com | Method and arrangement for issuance and management of digital coupons and sales offers |
AU3033500A (en) | 1999-01-15 | 2000-08-01 | Agouron Pharmaceuticals, Inc. | Non-peptide glp-1 agonists |
EP1171430A1 (de) | 1999-04-16 | 2002-01-16 | Dr. Reddy's Research Foundation | Polymorphe formen eines antidiabetischen agens: verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen diese enthaltend |
AU2953699A (en) | 1999-04-16 | 2000-11-02 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
WO2000063193A1 (en) | 1999-04-16 | 2000-10-26 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
EP1171438A1 (de) | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Verbindungen, ihre herstellung und ihre verwendung |
AU3957900A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
AU3958200A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
EP1171414A1 (de) | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Verbindungen, ihre herstellung und ihre anwendung |
JP2003531856A (ja) | 2000-05-02 | 2003-10-28 | スミスクライン・ビーチャム・コーポレイション | リン酸輸送阻害剤 |
US6790569B2 (en) | 2000-06-13 | 2004-09-14 | Eastman Kodak Company | Color photothermographic elements comprising phenolic thermal solvents |
BR0112658A (pt) | 2000-07-20 | 2003-06-24 | Hoffmann La Roche | Ativadores de benzeno-acetamida-glucoquinase substituìdos por alfa-acil e alfa heteroátomos |
JP2004067629A (ja) | 2002-08-09 | 2004-03-04 | Yamanouchi Pharmaceut Co Ltd | ミトコンドリア機能活性化剤及び新規なベンゾイミダゾール誘導体 |
US20040138301A1 (en) | 2002-11-08 | 2004-07-15 | Hansen Birgit Sehested | Chemical uncouplers for the treatment of obesity |
US7179832B2 (en) | 2003-01-23 | 2007-02-20 | Crystalgenomics, Inc. | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof |
JP2007503453A (ja) | 2003-05-14 | 2007-02-22 | ノボ ノルディスク アクティーゼルスカブ | 肥満症を治療するための新規化合物 |
AU2004292536A1 (en) | 2003-11-21 | 2005-06-09 | Arena Pharmaceuticals, Inc. | Methods for producing olfactory GPCRS |
BRPI0416933A (pt) * | 2003-11-25 | 2007-01-16 | Novo Nordisk As | composto, composição farmacêutica, método para tratar uma doença, uso de um composto, e, métodos para aumentar a respiração mitocondrial em um paciente, e para reduzir a quantidade de espécies de oxigênio reativas em um paciente |
JP2007536344A (ja) | 2004-05-04 | 2007-12-13 | ノボ ノルディスク アクティーゼルスカブ | 新規のインドール誘導体 |
CA2589363A1 (en) | 2004-12-13 | 2006-06-22 | Eli Lilly And Company | Spiro derivatives as lipoxygenase inhibitors |
WO2006066126A2 (en) | 2004-12-16 | 2006-06-22 | Symyx Technologies, Inc. | Phenol-heterocyclic ligands, metal complexes, and their uses as catalysts |
CA2669884A1 (en) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | Novel 2-(2-hydroxyphenyl)benzimidazoles useful for treating obesity and diabetes |
US20100249161A1 (en) | 2006-11-15 | 2010-09-30 | Anders Klarskov Petersen | 2- ( 2 -hydroxyphenyl) -quinazolin-4-ones useful for treating obesity and diabetes |
CA2669860A1 (en) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | New haloalkylsulfone substituted compounds useful for treating obesity and diabetes |
-
2007
- 2007-11-15 US US12/515,056 patent/US8022066B2/en not_active Expired - Fee Related
- 2007-11-15 CA CA002669874A patent/CA2669874A1/en not_active Abandoned
- 2007-11-15 WO PCT/EP2007/062408 patent/WO2008059025A1/en active Application Filing
- 2007-11-15 AT AT07822643T patent/ATE538109T1/de active
- 2007-11-15 EP EP07822643A patent/EP2086951B1/de not_active Not-in-force
- 2007-11-15 ES ES07822643T patent/ES2377322T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
WO2008059025A1 (en) | 2008-05-22 |
EP2086951B1 (de) | 2011-12-21 |
US20090325941A1 (en) | 2009-12-31 |
EP2086951A1 (de) | 2009-08-12 |
ES2377322T3 (es) | 2012-03-26 |
US8022066B2 (en) | 2011-09-20 |
CA2669874A1 (en) | 2008-05-22 |
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